MISC

2017年9月13日

Design of focal brain cooling system for suppressing epileptic seizures

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
  • Kei Hata
  • ,
  • Koichi Fujiwara
  • ,
  • Manabu Kano
  • ,
  • Takao Inoue
  • ,
  • Sadahiro Nomura
  • ,
  • Hirochika Imoto
  • ,
  • Michiyasu Suzuki

開始ページ
283
終了ページ
286
DOI
10.1109/EMBC.2017.8036817

© 2017 IEEE. Epilepsy is a group of diseases caused by excessive neuronal activities, and one-quarter of the patients do not become seizure-free by the existing treatments. The potential treatments include focal brain cooling, which aims to cool the region where the excessive neuronal activities begin. We are developing a focal brain cooling system. The system delivers cold saline to a cranially implanted cooling device. The outflow is cooled by a Peltier device and pumped for circulation. The Peltier device and the pump are activated only when a seizure is predicted. In this research, the length of time for cooling the brain was calculated with a computational fluid dynamics (CFD)-based model of the focal brain cooling system. As a result, it takes less than 10 minutes for the average temperature 2 mm below the cooling device to reach 25.0 °C. It is much shorter than the time from seizure prediction to seizure onset when an existing algorithm for prediction is used.

リンク情報
DOI
https://doi.org/10.1109/EMBC.2017.8036817
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29059865
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85032231303&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85032231303&origin=inward
ID情報
  • DOI : 10.1109/EMBC.2017.8036817
  • ISSN : 1557-170X
  • PubMed ID : 29059865
  • SCOPUS ID : 85032231303

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