論文

査読有り
2012年2月

Fabrication of Capillary-like Network in a Matrix of Water-soluble Polymer Using Poly(methyl methacrylate) Microfibers

ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
  • Takayuki Takei
  • ,
  • Naoya Kishihara
  • ,
  • Hiroyuki Ijima
  • ,
  • Koei Kawakami

40
1-2
開始ページ
66
終了ページ
69
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.3109/10731199.2011.592492
出版者・発行元
INFORMA HEALTHCARE

Poly(methyl methacrylate) (PMMA) microfibers were used as a template for development of a capillary-like network in agarose hydrogel. Microfibers with diameter 10-20 mu m, which is comparable to the diameter of native capillary vessels, were fabricated using a wet spinning technique. The microfibers were embedded in agarose gel and dissolved by immersing the gel in dichloromethane. The resultant microchannels in the gel had the same diameter as the microfibers, and allowed an aqueous solution to be perfused through the gel. The methodology is promising for fabricating a capillary-like network in tissue engineering scaffolds of various water-soluble polymers.

Web of Science ® 被引用回数 : 5

リンク情報
DOI
https://doi.org/10.3109/10731199.2011.592492
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/21732729
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000299696500009&DestApp=WOS_CPL