論文

査読有り 国際誌
2011年8月15日

Correlations between pretransplant dialysis duration, bladder capacity, and prevalence of vesicoureteral reflux to the graft.

Transplantation
  • Takamitsu Inoue
  • ,
  • Shigeru Satoh
  • ,
  • Mitsuru Saito
  • ,
  • Kazuyuki Numakura
  • ,
  • Hiroshi Tsuruta
  • ,
  • Takashi Obara
  • ,
  • Shintaro Narita
  • ,
  • Yohei Horikawa
  • ,
  • Norihiko Tsuchiya
  • ,
  • Tomonori Habuchi

92
3
開始ページ
311
終了ページ
5
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/TP.0b013e318223d7d6

BACKGROUND: Urinary bladder capacity is reduced in patients undergoing long-term dialysis, which may increase the risk of vesicoureteral reflux (VUR) to a transplanted kidney. This study investigated the correlations between dialysis duration, pretransplant and posttransplant bladder capacity, and prevalence of VUR to the graft. METHODS: Voiding cystography was performed in 101 adult renal transplant recipients without neurogenic disorders immediately before and 1 year after transplantation to evaluate bladder capacity and VUR. Nonstented extravesical antireflux ureteroneocystostomy was performed in all patients. RESULTS: The median dialysis duration and pretransplant bladder capacity were 32 months (range 1-426 months) and 120 mL (range 15-450 mL), and 21 patients (20.8%) underwent dialysis for more than 120 months, and 30 patients (29.7%) had a pretransplant bladder capacity of less than 80 mL. Dialysis duration was correlated with pretransplant bladder capacity (R=0.466, P<0.001). Bladder capacity expanded more than 6-fold from pretransplantation to posttransplantation, and all recipients had a bladder capacity greater than 150 mL at 1 year posttransplantation. Thirty patients had VUR to the graft. Dialysis duration longer than 60 months (P=0.021) and pretransplant bladder capacity of less than 130 mL (P=0.024) were associated with VUR. VUR was associated with lower graft function. CONCLUSIONS: Although bladder capacity decreased because of long-term dialysis, it exceeded 150 mL at 1 year posttransplantation. A small bladder can be used in renal transplantation, but it may increase the risk of VUR.

リンク情報
DOI
https://doi.org/10.1097/TP.0b013e318223d7d6
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/21659949

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