論文

査読有り 筆頭著者
2020年1月

Physical multimorbidity patterns and depressive symptoms: a nationwide cross-sectional study in Japan

Family Medicine and Community Health
  • Takuya Aoki
  • ,
  • Yosuke Yamamoto
  • ,
  • Sayaka Shimizu
  • ,
  • Shunichi Fukuhara

8
1
開始ページ
e000234
終了ページ
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.1136/fmch-2019-000234
出版者・発行元
BMJ

<sec><title>Objective</title>The associations of physical multimorbidity with depressive symptoms have been investigated in a number of studies. However, whether patterns of chronic physical conditions have comparatively different associations with depressive symptoms remains unclear. This study aimed to investigate the associations of physical multimorbidity patterns with depressive symptoms.

</sec><sec><title>Design</title>This study was designed as a nationwide cross-sectional survey in Japan.

</sec><sec><title>Setting</title>General sample of the Japanese population.

</sec><sec><title>Participants</title>Adult Japanese residents were selected by a quota sampling method. Data were analysed from 1788 residents who reported one or more chronic health conditions.

</sec><sec><title>Results</title>Among four physical multimorbidity patterns: cardiovascular-renal-metabolic (CRM), skeletal-articular-digestive (SAD), respiratory-dermal (RDE) and malignant-digestive-urologic (MDU), multivariable logistic regression analyses revealed that the RDE pattern showed the strongest association with depressive symptoms (aOR=1.68, 95% CI: 1.21 to 2.31 for the pattern score highest quartile, compared with the lowest quartile), followed by SAD and MDU patterns (aOR=1.41, 95% CI: 1.01 to 1.98 for the SAD pattern score highest quartile; 1.41, 95% CI: 1.01 to 1.96 for the MDU pattern score highest quartile, compared with the lowest quartile). In contrast, the CRM pattern score was not significantly associated with depressive symptoms (aOR=1.31, 95% CI: 0.90 to 1.89 for the pattern score highest quartile, compared with the lowest quartile).

</sec><sec><title>Conclusions</title>Physical multimorbidity patterns have different associations with depressive symptoms. Among these patterns, patients with the RDE pattern may be at a higher risk for developing depressive symptoms. This study reinforces the evidence that cluster pattern of chronic health conditions is a useful measure for clinical management of multimorbidity as it is differently associated with mental health status, which is one of the crucial outcomes for multimorbid patients.

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リンク情報
DOI
https://doi.org/10.1136/fmch-2019-000234
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32148733
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032897
URL
https://syndication.highwire.org/content/doi/10.1136/fmch-2019-000234
ID情報
  • DOI : 10.1136/fmch-2019-000234
  • ISSN : 2305-6983
  • eISSN : 2009-8774
  • PubMed ID : 32148733
  • PubMed Central 記事ID : PMC7032897

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