2013年10月17日
Molecular mechanism of strigolactone perception by DWARF14
Nature Communications
- 巻
- 4
- 号
- 開始ページ
- 2613
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1038/ncomms3613
- 出版者・発行元
- NATURE PUBLISHING GROUP
Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14 - SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.
- リンク情報
- ID情報
-
- DOI : 10.1038/ncomms3613
- ISSN : 2041-1723
- PubMed ID : 24131983
- Web of Science ID : WOS:000326472200002