論文

国際誌
2017年10月

International trends in antipsychotic use: A study in 16 countries, 2005-2014.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
  • Óskar Hálfdánarson
  • ,
  • Helga Zoëga
  • ,
  • Lise Aagaard
  • ,
  • Miquel Bernardo
  • ,
  • Lena Brandt
  • ,
  • Anna Coma Fusté
  • ,
  • Kari Furu
  • ,
  • Kristina Garuoliené
  • ,
  • Falk Hoffmann
  • ,
  • Krista F Huybrechts
  • ,
  • Luuk J Kalverdijk
  • ,
  • Koji Kawakami
  • ,
  • Helle Kieler
  • ,
  • Takuya Kinoshita
  • ,
  • Melisa Litchfield
  • ,
  • Soffy C López
  • ,
  • Jorge E Machado-Alba
  • ,
  • Manuel E Machado-Duque
  • ,
  • Mufaddal Mahesri
  • ,
  • Prasad S Nishtala
  • ,
  • Sallie-Anne Pearson
  • ,
  • Johan Reutfors
  • ,
  • Leena K Saastamoinen
  • ,
  • Izumi Sato
  • ,
  • Catharina C M Schuiling-Veninga
  • ,
  • Yu-Chiau Shyu
  • ,
  • Svetlana Skurtveit
  • ,
  • Hélène Verdoux
  • ,
  • Liang-Jen Wang
  • ,
  • Corinne Zara Yahni
  • ,
  • Christian J Bachmann

27
10
開始ページ
1064
終了ページ
1076
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.euroneuro.2017.07.001

The objective of this study was to assess international trends in antipsychotic use, using a standardised methodology. A repeated cross-sectional design was applied to data extracts from the years 2005 to 2014 from 16 countries worldwide. During the study period, the overall prevalence of antipsychotic use increased in 10 of the 16 studied countries. In 2014, the overall prevalence of antipsychotic use was highest in Taiwan (78.2/1000 persons), and lowest in Colombia (3.2/1000). In children and adolescents (0-19 years), antipsychotic use ranged from 0.5/1000 (Lithuania) to 30.8/1000 (Taiwan). In adults (20-64 years), the range was 2.8/1000 (Colombia) to 78.9/1000 (publicly insured US population), and in older adults (65+ years), antipsychotic use ranged from 19.0/1000 (Colombia) to 149.0/1000 (Taiwan). Atypical antipsychotic use increased in all populations (range of atypical/typical ratio: 0.7 (Taiwan) to 6.1 (New Zealand, Australia)). Quetiapine, risperidone, and olanzapine were most frequently prescribed. Prevalence and patterns of antipsychotic use varied markedly between countries. In the majority of populations, antipsychotic utilisation and especially the use of atypical antipsychotics increased over time. The high rates of antipsychotic prescriptions in older adults and in youths in some countries merit further investigation and systematic pharmacoepidemiologic monitoring.

リンク情報
DOI
https://doi.org/10.1016/j.euroneuro.2017.07.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28755801

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