2016年12月12日
Structure and Reactivity of an Asymmetric Synthetic Mimic of Nitrogenase Cofactor.
Angewandte Chemie (International ed. in English)
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- 巻
- 55
- 号
- 50
- 開始ページ
- 15633
- 終了ページ
- 15636
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/anie.201608806
The Mo nitrogenase catalyzes the ambient reduction of N2 to NH3 at its M-cluster site. A complex metallocofactor with a core composition of [MoFe7 S9 C], the M-cluster, can be extracted from the protein scaffold and used to facilitate the catalytic reduction of CN- , CO, and CO2 into hydrocarbons in the isolated state. Herein, we report the synthesis, structure, and reactivity of an asymmetric M-cluster analogue with a core composition of [MoFe5 S9 ]. This analogue, referred to as the Mo-cluster, is the first synthetic example of an M-cluster mimic with Fe and Mo positioned at opposite ends of the cluster. Moreover, the ability of the Mo-cluster to reduce C1 substrates to hydrocarbons suggests the feasibility of developing nitrogenase-based biomimetic approaches to recycle C1 waste into fuel products.
- ID情報
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- DOI : 10.1002/anie.201608806
- PubMed ID : 27862765