論文

国際誌
2005年4月

Antegrade selective cerebral perfusion with mild hypothermic systemic circulatory arrest during thoracic aortic surgery.

Scandinavian cardiovascular journal : SCJ
  • Toshio Kaneda
  • ,
  • Toshihiko Saga
  • ,
  • Masahiko Onoe
  • ,
  • Hitoshi Kitayama
  • ,
  • Susumu Nakamoto
  • ,
  • Terufumi Matsumoto
  • ,
  • Takehiro Inoue
  • ,
  • Masato Imura
  • ,
  • Tatsuya Ogawa
  • ,
  • Takako Nishino
  • ,
  • Kousuke Fujii

39
1-2
開始ページ
87
終了ページ
90
記述言語
英語
掲載種別
研究論文(学術雑誌)

OBJECTIVE: Antegrade selective cerebral perfusion (ASCP) and retrograde cerebral perfusion (RCP) have proven to be reliable methods of brain protection during aortic surgery. These techniques are usually accompanied by systemic circulatory arrest with moderate hypothermia (24-28 degrees C) or deep hypothermia (18-24 degrees C). However, hypothermia can lead to various problems. The present study therefore reports results for thoracic aorta replacement using ASCP with mild hypothermic systemic arrest (28-32 degrees C). DESIGN: Between 1995 and 2003, 68 consecutive patients underwent repair of the ascending aorta and/or aortic arch. Mild hypothermic ASCP was utilized in 31 cases, moderate hypothermic ASCP in 20, and deep hypothermic RCP in 17. Various parameters were compared between the mild hypothermic ASCP, moderate hypothermic ASCP, and RCP. RESULTS: Hospital mortality was 10.3%, with no significant differences observed between any groups. Permanent neurological dysfunction was 8.8%, and no significant differences were observed between any groups. Mild hypothermic ASCP displayed significantly decreased transfusion volume, intubation time, and ICU stay. CONCLUSIONS: Use of ASCP with mild hypothermic systemic circulatory arrest during aortic surgery resulted in acceptable hospital mortality and neurological outcomes. ASCP with mild hypothermic arrest allows decreased transfusion volume and reduced duration of intubation and ICU stay.

リンク情報
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/16097420
ID情報
  • ISSN : 1401-7431
  • PubMed ID : 16097420

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