原田拓 (Harada Taku) - マイポータル

基本情報

所属: 札幌医科大学医学部研究員

J-GLOBAL ID: 201901010948420946
researchmap会員ID: B000374567

研究キーワード

論文

Multiloop as a novel traction method in accelerating colorectal endoscopic submucosal dissection.

Yuichiro Suzuki, Tokuma Tanuma, Masanori Nojima, Gota Sudo, Masakazu Akahonai, Hidetaka Hamamoto, Hironori Aoki, Taku Harada, Akio Katanuma, Hiroshi Nakase

Gastrointestinal endoscopy 91(1) 185-190 2020年1月査読有り
Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors.

Taku Harada, Eiichiro Yamamoto, Hiro-O Yamano, Hironori Aoki, Hiro-O Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Yoshihito Tanaka, Yuko Yoshida …

Journal of gastroenterology 53(12) 1241-1252 2018年12月査読有り
Subtypes of the Type II Pit Pattern Reflect Distinct Molecular Subclasses in the Serrated Neoplastic Pathway.

Hironori Aoki, Eiichiro Yamamoto, Hiro-O Yamano, Tamotsu Sugai, Tomoaki Kimura, Yoshihito Tanaka, Hiro-O Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada …

Digestive diseases and sciences 63(7) 1920-1928 2018年7月査読有り
Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.

Hironori Aoki, Eiichiro Yamamoto, Akira Takasawa, Takeshi Niinuma, Hiro-O Yamano, Taku Harada, Hiro-O Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada …

Oncotarget 9(4) 4707-4721 2018年1月12日査読有り
Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors

Takeshi Niinuma, Masahiro Kai, Hiroshi Kitajima, Eiichiro Yamamoto, Taku Harada, Reo Maruyama, Takayuki Nobuoka, Toshirou Nishida, Tatsuo Kanda, Tadashi Hasegawa …

ONCOLOGY LETTERS 14(5) 5703-5710 2017年11月査読有り
Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer

Masahiro Kai, Eiichiro Yamamoto, Akiko Sato, Hiro-o Yamano, Takeshi Niinuma, Hiroshi Kitajima, Taku Harada, Hironori Aoki, Reo Maruyama, Mutsumi Toyota …

MOLECULAR CARCINOGENESIS 56(7) 1743-1752 2017年7月査読有り
TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells

Masahiro Kai, Takeshi Niinuma, Hiroshi Kitajima, Eiichiro Yamamoto, Taku Harada, Hironori Aoki, Reo Maruyama, Mutsumi Toyota, Yasushi Sasaki, Tamotsu Sugai …

PLOS ONE 11(12) e0168281 2016年12月査読有り
Assessment of epigenetic alterations in early colorectal lesions containing BRAF mutations

Takeshi Sawada, Eiichiro Yamamoto, Hiro-o Yamano, Masanori Nojima, Taku Harada, Reo Maruyama, Masami Ashida, Hironori Aoki, Hiro-o Matsushita, Kenjiro Yoshikawa …

ONCOTARGET 7(23) 35106-35118 2016年6月査読有り
Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors

Seiko Kamimae, Eiichiro Yamamoto, Masahiro Kai, Takeshi Niinuma, Hiro-o Yamano, Masanori Nojima, Kennjiro Yoshikawa, Tomoaki Kimura, Ryo Takagi, Eiji Harada …

ONCOTARGET 6(30) 29975-29990 2015年10月査読有り
Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator

Takuro Kameda, Kotaro Shide, Takumi Yamaji, Ayako Kamiunten, Masaaki Sekine, Yasuhiro Taniguchi, Tomonori Hidaka, Yoko Kubuki, Haruko Shimoda, Kousuke Marutsuka …

BLOOD 125(2) 304-315 2015年1月査読有り
Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer

Taku Harada, Eiichiro Yamamoto, Hiro-o Yamano, Masanori Nojima, Reo Maruyama, Kohei Kumegawa, Masami Ashida, Kenjiro Yoshikawa, Tomoaki Kimura, Eiji Harada …

CANCER PREVENTION RESEARCH 7(10) 1002-1010 2014年10月査読有り
Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk

Ryo Suzuki, Eiichiro Yamamoto, Masanori Nojima, Reo Maruyama, Hiro-o Yamano, Kenjiro Yoshikawa, Tomoaki Kimura, Taku Harada, Masami Ashida, Takeshi Niinuma …

JOURNAL OF GASTROENTEROLOGY 49(7) 1135-1144 2014年7月査読有り
Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization

Takeshi Sawada, Eiichiro Yamamoto, Hiromu Suzuki, Masanori Nojima, Reo Maruyama, Yoshihiro Shioi, Risaburo Akasaka, Seiko Kamimae, Taku Harada, Masami Ashida …

GENES CHROMOSOMES & CANCER 52(2) 140-149 2013年2月査読有り
Molecular Dissection of Premalignant Colorectal Lesions Reveals Early Onset of the CpG Island Methylator Phenotype

Eiichiro Yamamoto, Hiromu Suzuki, Hiro-o Yamano, Reo Maruyama, Masanori Nojima, Seiko Kamimae, Takeshi Sawada, Masami Ashida, Kenjiro Yoshikawa, Tomoaki Kimura …

AMERICAN JOURNAL OF PATHOLOGY 181(5) 1847-1861 2012年11月査読有り
Aberrant Methylation of RASGRF1 Is Associated with an Epigenetic Field Defect and Increased Risk of Gastric Cancer

Hiroyuki Takamaru, Eiichiro Yamamoto, Hiromu Suzuki, Masanori Nojima, Reo Maruyama, Hiro-o Yamano, Kenjiro Yoshikawa, Tomoaki Kimura, Taku Harada, Masami Ashida …

CANCER PREVENTION RESEARCH 5(10) 1203-1212 2012年10月査読有り
A Novel Pit Pattern Identifies the Precursor of Colorectal Cancer Derived From Sessile Serrated Adenoma

Tomoaki Kimura, Eiichiro Yamamoto, Hiro-o Yamano, Hiromu Suzuki, Seiko Kamimae, Masanori Nojima, Takeshi Sawada, Masami Ashida, Kenjiro Yoshikawa, Ryo Takagi …

AMERICAN JOURNAL OF GASTROENTEROLOGY 107(3) 460-469 2012年3月査読有り
Typical gastroduodenal endoscopic findings in a Crohn's disease patient in remission stage.

Iizuka M, Harada T, Yamano HO, Etou T, Sagara S

World journal of gastrointestinal endoscopy 4(3) 96-98 2012年3月査読有り
Epigenetic Alteration of DNA in Mucosal Wash Fluid Predicts Invasiveness of Colorectal Tumors

Seiko Kamimae, Eiichiro Yamamoto, Hiro-o Yamano, Masanori Nojima, Hiromu Suzuki, Masami Ashida, Tomo Hatahira, Akiko Sato, Tomoaki Kimura, Kenjiro Yoshikawa …

CANCER PREVENTION RESEARCH 4(5) 674-683 2011年5月査読有り
A case study: Interferon-beta-induced remission of ulcerative colitis in a patient with type C chronic hepatitis

Tadashi Miike, Yoshihiro Tahara, Yumi Yamaguchi, Taku Harada, Hiroo Abe, Kazunori Kusumoto, Masatsugu Numata, Satoru Hasuike, Shojiro Yamamoto, Mayumi Kodama …

Japanese Journal of Gastroenterology 105(9) 1362-1366 2008年査読有り

共同研究・競争的資金等の研究課題

大腸発がんに関わるスーパーエンハンサー領域の同定とその臨床応用

科学研究費補助金: 基盤研究C 2017年4月 - 2020年3月

原田拓
大腸発癌リスクを予測するヒストン修飾異常解明と個別化予防の確立

科学研究費補助金: 若手研究B 2015年4月 - 2017年3月

原田拓
大腸鋸歯状病変の画期的な存在・質的診断方法の開発

科学研究費補助金: 若手研究B 2013年4月 - 2016年3月

原田拓

産業財産権

特開2016-201999 大腸癌を検出する方法

鈴木拓, 山本英一郎, 山野泰穂, 原田拓