Toshiaki Teratani - My portal

Profile Information

Affiliation: 講師, 医学部消化器内科, 慶應義塾大学

Researcher number: 40624408
J-GLOBAL ID: 202001011118487220
researchmap Member ID: R000011736

Papers

The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis.

Kentaro Miyamoto, Tomohisa Sujino, Yosuke Harada, Hiroshi Ashida, Yusuke Yoshimatsu, Yuki Yonemoto, Yasuhiro Nemoto, Michio Tomura, Hassan Melhem, Jan Hendrik Niess …

Cell reports, 42(8) 113005-113005, Aug 29, 2023
Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development.

Keiko Ono, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Satoshi Kojo, Yusuke Yoshimatsu, Shun Tanemoto, Yuzo Koda, Jiawen Zheng, Kazutoshi Sayama …

Nature communications, 14(1) 5152-5152, Aug 24, 2023
IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis

Sota Fujimori, Po-Sung Chu, Toshiaki Teratani, Yosuke Harada, Takahiro Suzuki, Takeru Amiya, Nobuhito Taniki, Ryosuke Kasuga, Yohei Mikami, Yuzo Koda …

JHEP Reports, 5(7) 100757-100757, Jul, 2023
Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis

Masataka Ichikawa, Nobuhiro Nakamoto, Sharon Kredo-Russo, Eyal Weinstock, Iddo Nadav Weiner, Efrat Khabra, Noa Ben-Ishai, Dana Inbar, Noga Kowalsman, Ron Mordoch …

Nature Communications, 14(1) 3261-3261, Jun 5, 2023 Peer-reviewed
Myeloid TLR4 signaling promotes post-injury withdrawal resolution of murine liver fibrosis.

Yoichi Takimoto, Po-Sung Chu, Nobuhiro Nakamoto, Yuya Hagihara, Yohei Mikami, Kentaro Miyamoto, Rei Morikawa, Toshiaki Teratani, Nobuhito Taniki, Sota Fujimori …

iScience, 26(3) 106220-106220, Mar 17, 2023
CCR9 axis inhibition enhances hepatic migration of plasmacytoid DCs and protects against liver injury.

Yuzo Koda, Nobuhiro Nakamoto, Po-Sung Chu, Toshiaki Teratani, Akihisa Ueno, Takeru Amiya, Nobuhito Taniki, Sayako Chiba, Kentaro Miyamoto, Michiie Sakamoto …

JCI insight, 7(17), Sep 8, 2022
Neuroimmune crosstalk in the gut and liver.

Toshiaki Teratani, Yohei Mikami, Takanori Kanai

International immunology, 34(9) 475-484, Sep 6, 2022
[Role of the Vagus Nerve in the Gut-Brain Axis: Development and Maintenance of Gut Regulatory T Cells via the Liver-Brain-Gut Vago-Vagal Reflex].

Takanori Kanai, Toshiaki Teratani

Brain and nerve = Shinkei kenkyu no shinpo, 74(8) 971-977, Aug, 2022
Th17 cells in the liver: balancing autoimmunity and pathogen defense.

Nobuhito Taniki, Nobuhiro Nakamoto, Po-Sung Chu, Masataka Ichikawa, Toshiaki Teratani, Takanori Kanai

Seminars in immunopathology, 44(4) 509-526, Jul, 2022
Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut.

Yusuke Yoshimatsu, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Shun Tanemoto, Keiko Ono, Satoko Umeda, Kosuke Yoshida, Toshiaki Teratani, Takahiro Suzuki …

Cell reports, 39(6) 110773-110773, May 10, 2022
Organ and brain crosstalk: The liver-brain axis in gastrointestinal, liver, and pancreatic diseases.

Yuta Matsubara, Hiroki Kiyohara, Toshiaki Teratani, Yohei Mikami, Takanori Kanai

Neuropharmacology, 205 108915-108915, Mar 1, 2022
Vagus nerve-mediated intestinal immune regulation: therapeutic implications of inflammatory bowel diseases.

Yohei Mikami, Junya Tsunoda, Hiroki Kiyohara, Nobuhito Taniki, Toshiaki Teratani, Takanori Kanai

International immunology, 34(2) 97-106, Jan 22, 2022
Heterogeneity of ILC2s in the Intestine; Homeostasis and Pathology.

Shogo Sunaga, Junya Tsunoda, Toshiaki Teratani, Yohei Mikami, Takanori Kanai

Frontiers in immunology, 13 867351-867351, 2022
Enrichment of type I interferon signaling in colonic group 2 innate lymphoid cells in experimental colitis.

Emi Irie, Rino Ishihara, Ichiro Mizushima, Shunya Hatai, Yuya Hagihara, Yoshiaki Takada, Junya Tsunoda, Kentaro Iwata, Yuta Matsubara, Yusuke Yoshimatsu …

Frontiers in immunology, 13 982827-982827, 2022
Single-cell transcriptomics of human gut T cells identifies cytotoxic CD4⁺CD8A⁺ T cells related to mouse CD4 cytotoxic T cells.

Shun Tanemoto, Tomohisa Sujino, Kentaro Miyamoto, Jonathan Moody, Yusuke Yoshimatsu, Yoshinari Ando, Ikuko Koya, Yosuke Harada, Anna Okuzawa Tojo, Keiko Ono …

Frontiers in immunology, 13 977117-977117, 2022
CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells

Yuzo Koda, Toshiaki Teratani, Po-Sung Chu, Yuya Hagihara, Yohei Mikami, Yosuke Harada, Hanako Tsujikawa, Kentaro Miyamoto, Takahiro Suzuki, Nobuhito Taniki …

Nature Communications, 12(1) 4474-4474, Dec, 2021
Hepatic Adenosine Triphosphate Reduction Through the Short-Chain Fatty Acids-Peroxisome Proliferator-Activated Receptor γ-Uncoupling Protein 2 Axis Alleviates Immune-Mediated Acute Hepatitis in Inulin-Supplemented Mice.

Akihiro Yamaguchi, Toshiaki Teratani, Po-Sung Chu, Takahiro Suzuki, Nobuhito Taniki, Yohei Mikami, Shunsuke Shiba, Rei Morikawa, Takeru Amiya, Ryo Aoki …

Hepatology communications, 5(9) 1555-1570, Sep, 2021
Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption.

Shunsuke Shiba, Nobuhiro Nakamoto, Po-Sung Chu, Keisuke Ojiro, Nobuhito Taniki, Akihiro Yamaguchi, Rei Morikawa, Tadashi Katayama, Aya Yoshida, Ryo Aoki …

Scientific reports, 11(1) 13690-13690, Jul 1, 2021
Angiopoietin‐like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells

Toshiaki Teratani, Kengo Tomita, Akinori Wada, Nao Sugihara, Masaaki Higashiyama, Kenichi Inaba, Kazuki Horiuchi, Yoshinori Hanawa, Shin Nishii, Akinori Mizoguchi …

Hepatology Research, 51(5) 580-592, May, 2021
Pulmonary Arterial Hypertension Caused by AhR Signal Activation Protecting against Colitis.

Takahiro Hiraide, Toshiaki Teratani, Shizuka Uemura, Yusuke Yoshimatsu, Makoto Naganuma, Yoshiki Shinya, Mizuki Momoi, Eiji Kobayashi, Yoji Hakamata, Keiichi Fukuda …

American journal of respiratory and critical care medicine, 203(3) 385-388, Feb 1, 2021

Misc.

ROLES OF CD8+TISSUE-RESIDENT MEMORY T CELLS IN LIVER FIBROSIS RESOLUTION

Yuzo Koda, Toshiaki Teratani, Po-Sung Chu, Nobuhito Taniki, Takanori Kanai, Nobuhiro Nakamoto

HEPATOLOGY, 74 829A-830A, Oct, 2021
肝臓-脳-腸神経連関を介した新規腸管免疫制御機構の検討

寺谷俊昭, 三上洋平, 中本伸宏, 鈴木貴博, 原田洋輔, 萩原裕也, 谷木信仁, 宮本健太郎, 猪柏松, 筋野智久 …

日本潰瘍学会プログラム・抄録集, 48th, 2021
The herbal medicine 'Indigo naturalis' altered gut microbiota to accumulate IL-22(+) ILC3s

Yusuke Yoshimatsu, Toshiaki Teratani, Tomohisa Sujino, Yohei Mikami, Masataka Ichikawa, Yuya Hagihara, Yoshiaki Takada, Shun Tanemoto, Satoko Umeda, Ena Nomura …

JOURNAL OF IMMUNOLOGY, 204(1), May, 2020
INULIN INHIBITS ACUTE LIVER INJURY IN MICE THROUGH INHIBITION OF NEUTROPHIL INFILTRATION BY REDUCING ATP IN THE LIVER

Akihiro Yamaguchi, Nobuhiro Nakamoto, Toshiaki Teratani, Takahiro Suzuki, Shunsuke Shiba, Rei Morikawa, Nobuhito Taniki, Po-Sung Chu, Takanori Kanai

HEPATOLOGY, 70 1160A-1160A, Oct, 2019
gut-liver-brain axisによるマウス大腸炎抑制制御メカニズム

寺谷俊昭, 三上洋平, 筋野智久, 中本伸宏, 鈴木貴博, 谷木信人, 水野慎大, 長沼誠, 金井隆典

日本神経消化器病学会プログラム・抄録集, 20th, 2018

Research Projects

肝疾患病態進展による腸-肝臓-脳自律神経反射の破綻が諸臓器に及ぼす影響について

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2024

寺谷俊昭
宿主侵入菌に対する腸管免疫応答を介した消化器免疫難病の病態解明

科学研究費助成事業基盤研究(A), 基盤研究(A), 日本学術振興会, Apr, 2020 - Mar, 2023

金井隆典, 寺谷俊昭, 三上洋平
The elucidation of the World of AhR in the intestinal environment ,followed by the diverse clinical applications.

Grants-in-Aid for Scientific Research, Fund for the Promotion of Joint International Research (Fostering Joint International Research (B)), Japan Society for the Promotion of Science, Feb, 2019 - Mar, 2021

KANAI Takanori
Study of the role of the vagal liver branch in the onset and progression mechanism of nonalcoholic steatohepatitis.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

TERATANI Toshiaki
Investigation of the mechanisms for inhibitory effects on colonic inflammation and cancer of indigo naturalis including indole compounds

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Naganuma Makoto, Toshiaki Teratani, Mizuno Shinta
Role of gut microbiota in the pathogenesis of primly sclerosing cholangitis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

NAKAMOTO NOBUHIRO, CHU Po-Sung, TANIKI Nobuhito, TERATANI Toshiaki
The role of oxidative stress for progression of fatty liver disease

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Teratani Toshiaki, SHIMIZU Takahiko
Study on the mechanism of free cholesterol metabolism of hepatic stellate cell in liver fibrosis

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

TERATANI TOSHIAKI