Terauchi Tsutomu

Profile Information

Affiliation: Taiyo Nippon Sanso Corporation

Degree: 博士(理学)(東京都立大学)

J-GLOBAL ID: 201501069207194684
researchmap Member ID: B000246669

Research Interests

Research Areas

Research History

Apr, 2021 - Present

Taiyo Nippon Sanso Corporation
Oct, 2004 - Present

SAIL Technologies Inc.
Apr, 2015 - Mar, 2021

Taiyo Nippon Sanso Corporation
Apr, 2000 - Mar, 2008

Japan Science and Technology Agency

Papers

Conformational features and ionization states of Lys side chains in a protein studied using the stereo-array isotope labeling (SAIL) method

Mitsuhiro Takeda, Yohei Miyanoiri, Tsutomu Terauchi, Masatsune Kainosho

Magnetic Resonance, 2(1) 223-237, Apr 26, 2021
Recent developments in isotope-aided NMR methods for supramolecular protein complexes –SAIL aromatic TROSY

Yohei Miyanoiri, Mitsuhiro Takeda, Tsutomu Terauchi, Masatsune Kainosho

Biochimica et Biophysica Acta - General Subjects, 1864(2) 129439-129439, Feb, 2020
Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific ¹H-¹³C Labeling and Fast Magic-Angle Spinning NMR

Diego F. Gauto, Pavel Macek, Alessandro Barducci, Hugo Fraga, Audrey Hessel, Tsutomu Terauchi, David Gajan, Yohei Miyanoiri, Jerome Boisbouvier, Roman Lichtenecker …

Journal of the American Chemical Society, 141(28) 11183-11195, Jun 14, 2019
Perspective: next generation isotope-aided methods for protein NMR spectroscopy

Masatsune Kainosho, Yohei Miyanoiri, Tsutomu Terauchi, Mitsuhiro Takeda

Journal of Biomolecular NMR, 71(3) 119-127, Jul 1, 2018
¹³C-NMR studies on disulfide bond isomerization in bovine pancreatic trypsin inhibitor (BPTI)

Mitsuhiro Takeda, Yohei Miyanoiri, Tsutomu Terauchi, Masatsune Kainosho

Journal of Biomolecular NMR, 66(1) 37-53, Sep 1, 2016
Highly efficient residue-selective labeling with isotope-labeled Ile, Leu, and Val using a new auxotrophic E. coli strain

Yohei Miyanoiri, Yojiro Ishida, Mitsuhiro Takeda, Tsutomu Terauchi, Masayori Inouye, Masatsune Kainosho

Journal of Biomolecular NMR, 65(2) 109-119, Jun 1, 2016
Differential Large-Amplitude Breathing Motions in the Interface of FKBP12-Drug Complexes

Chun Jiun Yang, Mitsuhiro Takeda, Tsutomu Terauchi, Jun Goo Jee, Masatsune Kainosho

Biochemistry, 54(47) 6983-6995, Nov 11, 2015
Nano-mole scale sequential signal assignment by ¹H-detected protein solid-state NMR

Songlin Wang, Sudhakar Parthasarathy, Yiling Xiao, Yusuke Nishiyama, Fei Long, Isamu Matsuda, Yuki Endo, Takahiro Nemoto, Kazuo Yamauchi, Tetsuo Asakura …

Chemical Communications, 51(81) 15055-15058, Aug 14, 2015
Nano-mole scale side-chain signal assignment by¹H-detected protein solid-state NMR by ultra-fast magic-angle spinning and stereo-array isotope labeling

Songlin Wang, Sudhakar Parthasarathy, Yusuke Nishiyama, Yuki Endo, Takahiro Nemoto, Kazuo Yamauchi, Tetsuo Asakura, Mitsuhiro Takeda, Tsutomu Terauchi, Masatsune Kainosho …

PLoS ONE, 10(4) e0122714, Apr, 2015
Use of H/D isotope effects to gather information about hydrogen bonding and hydrogen exchange rates

Mitsuhiro Takeda, Yohei Miyanoiri, Tsutomu Terauchi, Chun Jiun Yang, Masatsune Kainosho

Journal of Magnetic Resonance, 241(1) 148-154, Apr, 2014
Differential isotope-labeling for Leu and Val residues in a protein by E. coli cellular expression using stereo-specifically methyl labeled amino acids

Yohei Miyanoiri, Mitsuhiro Takeda, Kosuke Okuma, Akira M. Ono, Tsutomu Terauchi, Masatsune Kainosho

Journal of Biomolecular NMR, 57(3) 237-249, Nov, 2013
Conformational analysis by quantitative NOE measurements of the β-proton pairs across individual disulfide bonds in proteins

Mitsuhiro Takeda, Tsutomu Terauchi, Masatsune Kainosho

Journal of Biomolecular NMR, 52(2) 127-139, Feb, 2012
Alternative SAIL-Trp for robust aromatic signal assignment and determination of the χ<inf>2</inf> conformation by intra-residue NOEs

Yohei Miyanoiri, Mitsuhiro Takeda, Jungoo Jee, Akira M. Ono, Kosuke Okuma, Tsutomu Terauchi, Masatsune Kainosho

Journal of Biomolecular NMR, 51(4) 425-435, Dec, 2011
Hydrogen exchange study on the hydroxyl groups of serine and threonine residues in proteins and structure refinement using NOE restraints with polar side-chain groups

Mitsuhiro Takeda, Jungoo Jee, Akira M. Ono, Tsutomu Terauchi, Masatsune Kainosho

Journal of the American Chemical Society, 133(43) 17420-17427, Nov 2, 2011
Synthesis of stereoarray isotope labeled (SAIL) lysine via the "head-to-tail" conversion of SAIL glutamic acid

Tsutomu Terauchi, Tomoe Kamikawai, Maxim G. Vinogradov, Eugenia V. Starodubtseva, Mitsuhiro Takeda, Masatsune Kainosho

Organic Letters, 13(1) 161-163, Jan 7, 2011
Detection of the sulfhydryl groups in proteins with slow hydrogen exchange rates and determination of their proton/deuteron fractionation factors using the deuterium-induced effects on the ¹³C<inf>β</inf> NMR signals

Mitsuhiro Takeda, Jun Goo Jee, Tsutomu Terauchi, Masatsune Kainosho

Journal of the American Chemical Society, 132(17) 6254-6260, May 5, 2010
Application of SAIL phenylalanine and tyrosine with alternative isotope-labeling patterns for protein structure determination

Mitsuhiro Takeda, Akira M. Ono, Tsutomu Terauchi, Masatsune Kainosho

Journal of Biomolecular NMR, 46(1) 45-49, Jan, 2010
Hydrogen exchange rate of tyrosine hydroxyl groups in proteins as studied by the deuterium isotope effect on Cζ chemical shifts

Mitsuhiro Takeda, Jun Goo Jee, Akira Mei Ono, Tsutomu Terauchi, Masatsune Kainosho

Journal of the American Chemical Society, 131(51) 18556-18562, Dec 30, 2009
[Progress in structural studies of larger proteins by the SAIL-NMR method].

Mitsuhiro Takeda, Tsutomu Terauchi, Akira Mei Ono, Masatsune Kainosho

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54(12 Suppl) 1506-1511, Sep, 2009
Assymetric synthesis of (2S,3R)- and (2S,3S)-[2-¹³C;3-²H] glutamic acid

Kosuke Okuma, Akira M. Ono, Seiji Tsuchiya, Makoto Oba, Kozaburo Nishiyama, Masatsune Kainosho, Tsutomu Terauchi

Tetrahedron Letters, 50(13) 1482-1484, Apr, 2009

Misc.

Py試薬を用いた脳内カテコールアミンの代謝解析

平修, 池田明夏里, 横山順, 寺内勉, 小林彰子

質量分析総合討論会講演要旨集, 67th, 2019
次世代定量メタボローム解析に資する安定同位体標識内部標準品群調製法の開発

相馬悠希, 藤原由梨, 高橋政友, 後藤麻衣子, 下平武彦, 池田明夏里, 寺内勉, 和泉自泰, 馬場健史, 馬場健史

日本生物工学会大会講演要旨集, 71st, 2019
核緩和機構最適化アミノ酸を利用した高分子量蛋白質の動態構造解析法の開発

宮ノ入洋平, 宮ノ入洋平, 武田光広, 武田光広, 寺内勉, 寺内勉, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 58th (CD-ROM), 2019
ピリリウム系誘導体化試薬による脳内タウリンおよびGABAの動態解析

池田明夏里, 龍田幸奈, 寺内勉, 村上茂, 平修

質量分析総合討論会講演要旨集, 66th, 2018
新規安定同位体標識技術を利用した高分子量蛋白質の動態構造解析法の開発

宮ノ入洋平, 武田光広, 寺内勉, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 57th, 2018
新規誘導体化試薬「Py-Tag」を用いたヒスタミン分析方法の検討

池田明夏里, 寺内勉, 横山順, 安本三穗, 寳龍久枝, 朝倉敬行, 中里光男

日本食品衛生学会学術講演会講演要旨集, 112th, 2016
核緩和最適化SAILアミノ酸を利用した高分子量蛋白質複合体の溶液立体構造解析法の開発

宮ノ入洋平, 武田光広, 寺内勉, 寺内勉, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 54th, 2015
大腸菌蛋白質生合成系を利用した新規SAILアミノ酸標識法の開発

宮ノ入洋平, 石田洋二郎, 武田光広, 寺内勉, 寺内勉, 井上正順, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 53rd, 2014
大腸菌を用いた大量発現系によるアミノ酸選択標識技術の最適化

寺内勉, 宮ノ入洋平, 武田光広, 近藤早恵, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 52nd, 2013
蛋白質リジン残基側鎖アミノ基の水素交換速度の解析

武田光広, 寺内勉, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 52nd, 2013
高分子量蛋白質の立体構造解析に向けた新規SAILアミノ酸標識法の開発

宮ノ入洋平, 武田光広, 寺内勉, 寺内勉, 甲斐荘正恒, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 52nd, 2013
SAIL-NMR法によるジスルフィド結合の立体配座決定と動態解析

武田光広, 寺内勉, 寺内勉, 甲斐荘正恒, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 51st, 2012
SAIL法による巨大蛋白質の新規立体構造解析法の開発

宮ノ入洋平, 武田光広, 大熊宏昌, 小野明, 寺内勉, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 51st, 2012
蛋白質側鎖OH/SHの水素交換速度の解析

武田光広, YANG Chun-Jiun, JEE JunGoo, 小野明, 寺内勉, 甲斐荘正恒, 甲斐荘正恒

Abstracts. Annual Meeting of the NMR Society of Japan, 49th, 2010
SAIL法による高分子量蛋白質の立体構造解析 (生命秩序を担う生体超分子) -- (超分子システム研究法のフロンティア)

鳥澤拓也, 寺内勉, 小野明

蛋白質核酸酵素, 50(10) 1375-1381, Aug, 2005
Syntheses of stereo-array isotope-labeled amino acids using SAIL L-serine as a key intermediate

小林久仁子, 寺内勉, 小野明, 甲斐荘正恒

日本化学会講演予稿集, 85th(2), 2005
SAIL法による高分子量タンパク質のNMR解析に向けた取り組みの現状

鳥沢拓也, 寺内勉, 岩下由紀, 杉森望, 小野明, 土屋征司, 田井真由理, GUENTERT P, 甲斐荘正恒

NMR討論会講演要旨集, 43rd, 2004
NMRによる高分子量タンパク質の立体構造決定への新手法の開発

岩下由紀, 鳥沢拓也, 寺内勉, 甲斐荘正恒

日本分子生物学会年会プログラム・講演要旨集, 26th, 2003
立体整列同位体標識(SAIL)法の開発~高分子量タンパク質の高効率,高精度な立体構造決定に向けて

鳥沢拓也, 寺内勉, 小野明, 甲斐荘正恒

NMR討論会講演要旨集, 42nd, 2003
立体整列同位体標識(SAIL)法による分子量42kDaのタンパク質・MBPの立体構造決定

岩下由紀, 鳥沢拓也, 寺内勉, 甲斐荘正恒

NMR討論会講演要旨集, 42nd, 2003

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