In standard finite element analysis in structural dynamics, meshing can affect computation results. However, there have been no detailed report about effects of meshing on results of coupling simulation of left ventricular wall motion which involves myocardial spontaneous contractile force and fiber orientation. In this study, we examined an effect of meshing on simulation of left ventricular wall motion, which couples precise ventricular myocyte model and myocardial fiber orientation. We compared two shape models
spheroid mesh divided along graticule and spheroid mesh subdivided from a semi-regular polyhedron. The comparison results show significant differences between two models around the ventricular apex, which are mainly caused by the contractile force and the fiber orientation.