1998年5月
Assessment of hepatic portal perfusion using T2* measurements of Gd-DTPA
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
- 巻
- 8
- 号
- 3
- 開始ページ
- 650
- 終了ページ
- 654
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/jmri.1880080320
- 出版者・発行元
- JOHN WILEY & SONS INC
Recently, perfusion imaging has been of increasing interest in MRI, We applied this method for semiquantitative evaluation of hepatic parenchymal portal blood now in patients with diffuse liver damage, Twenty patients with diffuse hepatic damage were divided according to the Child's Classification and studied. Gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) was administered into the superior mesenteric artery (SMA), and a dynamic series of T2*-weighted fast low angle shot (FLASH) images was obtained. We evaluated relative regional portal blood volume (rrPBV), mean transit time (MTT), and relative regional portal blood now (rrPBF), The relationship between the rrPBV, rrPBF, and plasma indocyanine green retention rate test at 15 minutes (ICGR(15)) was also evaluated in 12 patients. Both rrPBF and rrPBV are significantly decreased in Child B & C patients compared with Child A patients, On the other hand, the MTT is significantly prolonged in Child B & C patients compared with Child A patients. Significant correlations were also noted between rrPBV and ICGR(15) and between rrPBF and ICGR(15). By means of selective catheterization into the SMA, we were able to estimate rrPBV, rrPBF, and MTT. This method may play a clinical role for assessment of regional portal perfusion in various diseases with diffuse liver damage.
- リンク情報
- ID情報
-
- DOI : 10.1002/jmri.1880080320
- ISSN : 1053-1807
- Web of Science ID : WOS:000080143400019