論文

査読有り
2005年7月

Chronic food restriction enhances memory in mice - analysis with matched drive levels

NEUROREPORT
  • Teruo Hashimoto
  • ,
  • S Watanabe

16
10
開始ページ
1129
終了ページ
1133
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/00001756-200507130-00019
出版者・発行元
LIPPINCOTT WILLIAMS & WILKINS

We compared the effects of chronic and acute food deprivation on learning and memory using a dry-type water maze, active avoidance and passive avoidance in C57BL/6L mice. The drive level of the animals - under acute and chronic food deprivation - was matched by a progressive ratio schedule. Both deprivations led to a high degree of activity in the animals; however, the animals on an acute dietary restriction did not exhibit a significantly better performance than those on ad libitum feeding, while those on a chronic food deprivation exhibited memory enhancement. These effects were subtle and were found at a later stage of learning. These findings suggest that chronic food restriction induces memory consolidation or resistance to memory reduction in addition to increased activity.

リンク情報
DOI
https://doi.org/10.1097/00001756-200507130-00019
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000230772100019&DestApp=WOS_CPL
ID情報
  • DOI : 10.1097/00001756-200507130-00019
  • ISSN : 0959-4965
  • Web of Science ID : WOS:000230772100019

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