2016年
Myeloperoxidase Antineutrophil Cytoplasmic Antibody (MPO-ANCA) Associated Crescentic and Necrotizing Glomerulonephritis (GN) with Membranoproliferative GN Features
INTERNAL MEDICINE
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- 巻
- 55
- 号
- 15
- 開始ページ
- 2043
- 終了ページ
- 2048
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2169/internalmedicine.55.6426
- 出版者・発行元
- JAPAN SOC INTERNAL MEDICINE
A 77-year-old man presented with a fever, non-productive cough, and edema formation. A laboratory analysis showed an elevated creatinine level (2.5 mg/dL), a high titer of myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA) (99 U/mL), positive reaction for antinuclear antibody (x320), hematuria, and massive proteinuria (3.33 g/day). A renal biopsy revealed crescentic and necrotizing glomerulonephritis (GN) with membranoproliferative GN features [double contour appearance of the glomerular basement membrane, granular deposition of immunoglobulin (Ig) G, IgM, and C3 along the capillary wall, subendothelial and subepithelial deposits with mesangial interposition]. A potential relationship between MPO-ANCA associated GN and membranoproliferative GN is discussed.
- リンク情報
- ID情報
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- DOI : 10.2169/internalmedicine.55.6426
- ISSN : 0918-2918
- eISSN : 1349-7235
- PubMed ID : 27477412
- Web of Science ID : WOS:000380801500017