2021年5月13日
Early-phase migration dynamics of Echinococcus multilocularis in two mouse strains showing different infection susceptibilities.
International journal for parasitology
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- 巻
- 51
- 号
- 11
- 開始ページ
- 893
- 終了ページ
- 898
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.ijpara.2021.04.001
The early-phase migration dynamics of Echinococcus multilocularis in the intermediate hosts remain largely unknown. We compared the parasite burden in the intestine, liver and faeces of DBA/2 and C57BL/6 mouse strains using parasite-specific quantitative PCR. Our results indicated that the parasites invaded mainly from the middle segments of the small intestine and completed migration to the liver within 24 h p.i. C57BL/6 mice had lower parasite DNA burdens in the intestine and liver but higher in the faeces than DBA/2 mice, suggesting that parasite invasion of the intestine may be a critical stage regulating susceptibility to E. multilocularis infection in mice.
- リンク情報
- ID情報
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- DOI : 10.1016/j.ijpara.2021.04.001
- PubMed ID : 33991567