持田泰佑 (Taisuke Mochida) - マイポータル

基本情報

所属: 武田薬品工業株式会社主任研究員

J-GLOBAL ID: 202001012697706938
researchmap会員ID: R000002139

論文

Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.

Hideyuki Hiyoshi, Kensuke Sakuma, Shinya Asano, Stephanie C Napier, Shuhei Konagaya, Taisuke Mochida, Hikaru Ueno, Takeshi Watanabe, Yoshiaki Kassai, Hirokazu Matsumoto …

Proceedings of the National Academy of Sciences of the United States of America 121(16) e2320883121 2024年4月16日
Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC.

Hideyuki Hiyoshi, Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Shinya Asano, Taisuke Mochida, Junji Yamaura, Shuhei Konagaya, Ryo Fujii, Hirokazu Matsumoto, Ryo Ito …

Scientific reports 12(1) 4740-4740 2022年3月18日
Insulin-Deficient Diabetic Condition Upregulates the Insulin-Secreting Capacity of Human Induced Pluripotent Stem Cell-Derived Pancreatic Endocrine Progenitor Cells After Implantation in Mice.

Taisuke Mochida, Hikaru Ueno, Noriko Tsubooka-Yamazoe, Hideyuki Hiyoshi, Ryo Ito, Hirokazu Matsumoto, Taro Toyoda

Diabetes 69(4) 634-646 2020年4月査読有り
Inhibition of MGAT2 modulates fat-induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high-fat diet.

Taisuke Mochida, Kazumi Take, Toshiyuki Maki, Masanori Nakakariya, Ryutaro Adachi, Kenjiro Sato, Tomoyuki Kitazaki, Shiro Takekawa

FEBS open bio 10(3) 316-326 2020年3月査読有り
Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives.

Ayumu Niida, Yoko Kanematsu-Yamaki, Tomoko Asakawa, Yoshimasa Ishimura, Hisashi Fujita, Kouta Matsumiya, Naoki Nishizawa, Yusuke Adachi, Taisuke Mochida, Kazue Tsuchimori …

Bioorganic & medicinal chemistry 26(3) 566-572 2018年2月1日査読有り
Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide.

Yoko Kanematsu-Yamaki, Naoki Nishizawa, Tomoko Kaisho, Hiroaki Nagai, Taisuke Mochida, Tomoko Asakawa, Hiroshi Inooka, Katsuko Dote, Hisashi Fujita, Kouta Matsumiya …

Journal of medicinal chemistry 60(14) 6089-6097 2017年7月27日査読有り
Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization.

Kazumi Take, Taisuke Mochida, Toshiyuki Maki, Yoshinori Satomi, Megumi Hirayama, Masanori Nakakariya, Nobuyuki Amano, Ryutaro Adachi, Kenjiro Sato, Tomoyuki Kitazaki …

PloS one 11(3) e0150976 2016年査読有り
Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors.

Kenjiro Sato, Hiroki Takahagi, Takeshi Yoshikawa, Shinji Morimoto, Takafumi Takai, Kousuke Hidaka, Masahiro Kamaura, Osamu Kubo, Ryutaro Adachi, Tsuyoshi Ishii …

Journal of medicinal chemistry 58(9) 3892-909 2015年5月14日査読有り
The corn protein, zein hydrolysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-IV activity in rats.

Taisuke Mochida, Tohru Hira, Hiroshi Hara

Endocrinology 151(7) 3095-104 2010年7月査読有り
GLP-1 secretion is enhanced directly in the ileum but indirectly in the duodenum by a newly identified potent stimulator, zein hydrolysate, in rats.

Tohru Hira, Taisuke Mochida, Kyoko Miyashita, Hiroshi Hara

American journal of physiology. Gastrointestinal and liver physiology 297(4) G663-71 2009年10月査読有り

MISC

Corn protein hydrolysate stimulates GLP-1 secretion and attenuates hyperglycaemia in rats

T. Hira, T. Mochida, H. Hara

REGULATORY PEPTIDES 164(1) 43-43 2010年9月
ラットにおけるトウモロコシZein加水分解物によるGLP-1分泌を介した血糖上昇抑制 ([日本アミノ酸学会]第4回学術大会(JSAAS2010))

比良徹, 持田泰佑, 原博

アミノ酸研究 4(2) 163-166 2010年

持田泰佑

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