Tomomi Kuwahara

Profile Information

Affiliation: Faculty of Medicine, Kagawa University

Degree: (BLANK)
医学博士(徳島大学)

J-GLOBAL ID: 200901099901088831
researchmap Member ID: 1000182465

External link: http://www.med.kagawa-u.ac.jp/faculty/center/igaku_kouza/bunshi_biseibutsu/

Research Interests

Research Areas

Research History

Education

- 1993

Faculty of Medicine, The University of Tokushima
- 1993

Faculty of Medicine, The University of Tokushima

Awards

感染症学会優秀論文賞

Papers

104

Partially hydrolyzed guar gum alleviates hepatic steatosis and alters specific gut microbiota in a murine liver injury model

Takayuki Fujii, Haruyuki Nakayama-Imaohji, Aya Tanaka, Hiroto Katami, Kazuya Tanaka, Yoichi Chiba, Machi Kawauchi, Masaki Ueno, Tomomi Kuwahara, Ryuichi Shimono

Pediatric Surgery International, Sep 12, 2022
MetaPlatanus: a metagenome assembler that combines long-range sequence links and species-specific features.

Rei Kajitani, Hideki Noguchi, Yasuhiro Gotoh, Yoshitoshi Ogura, Dai Yoshimura, Miki Okuno, Atsushi Toyoda, Tomomi Kuwahara, Tetsuya Hayashi, Takehiko Itoh

Nucleic acids research, 49(22) e130, Dec 16, 2021
Inactivation of human norovirus by chlorous acid water, a novel chlorine-based disinfectant.

Hisataka Goda, Haruyuki Nakayama-Imaohji, Hitoshi Yamaoka, Ayano Tada, Tamiko Nagao, Tomohiko Fujisawa, A Hajime Koyama, Tomomi Kuwahara

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Oct 9, 2021
The Human Gut Microbe Bacteroides thetaiotaomicron Suppresses Toxin Release from Clostridium difficile by Inhibiting Autolysis.

Miad Elahi, Haruyuki Nakayama-Imaohji, Masahito Hashimoto, Ayano Tada, Hisashi Yamasaki, Tamiko Nagao, Tomomi Kuwahara

Antibiotics (Basel, Switzerland), 10(2), Feb 15, 2021
Presence of Acanthamoeba and diversified bacterial flora in poorly maintained contact lens cases

Dai Miyazaki, Hiroshi Eguchi, Tomomi Kuwahara, Haruyuki Nakayama-Imaohji, Masamaru Inaba, Motozumi Itoi, Kiichi Ueda, Yuichi Ohashi, Kazushige Sado, Satoshi Mizutani, Hitoshi Miyamoto, Shin-ichi Sasaki, Yumiko Shimizu, Yoshitsugu Inoue

Scientific Reports, 10(1), Dec, 2020
Microbiome analysis of contact lens care solutions and tear fluids of contact lens wearers: Possible involvement of streptococcal antigens in allergic symptoms related to contact lens wear.

Fumika Hotta, Hiroshi Eguchi, Haruyuki Nakayama-Imaohji, Tomomi Kuwahara, Ayano Tada, Hirofumi Yagi, Yoshikazu Shimomura, Shunji Kusaka

International journal of molecular medicine, 46(4) 1367-1376, Oct, 2020
D-Tagatose Effectively Reduces the Number of Streptococcus mutans and Oral Bacteria in Healthy Adult Subjects: A Chewing Gum Pilot Study and Randomized Clinical Trial.

Yuichi Nagamine, Khaleque Hasibul, Takaaki Ogawa, Ayano Tada, Kazuyo Kamitori, Akram Hossain, Fuminori Yamaguchi, Masaaki Tokuda, Tomomi Kuwahara, Minoru Miyake

Acta medica Okayama, 74(4) 307-317, Aug, 2020
Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation.

Ayano Tada, Haruyuki Nakayama-Imaohji, Hisashi Yamasaki, Miad Elahi, Tamiko Nagao, Hirofumi Yagi, Masao Ishikawa, Koji Shibuya, Tomomi Kuwahara

Molecular medicine reports, 22(2) 643-650, Aug, 2020 Peer-reviewed
非結核性抗酸菌に対する亜塩素酸水(HClO2)製剤の不活化効果

山岡徹, 今大路治之, 多田彩乃, 合田学剛, 桑原知巳

感染症学雑誌, 94(臨増) 279-279, Mar, 2020
【小児外科領域における感染症-基礎編】腸内細菌叢と抗菌薬との関連

田中彩, 下野隆一, 今大路治之, 桑原知巳

小児外科, 52(1) 45-49, Jan, 2020
Partially hydrolyzed guar gum alleviates small intestinal mucosal damage after massive small bowel resection along with changes in the intestinal microbiota.

Takayuki Fujii, Yoichi Chiba, Haruyuki Nakayama-Imaohji, Shun Onishi, Aya Tanaka, Hiroto Katami, Tatsuru Kaji, Satoshi Ieiri, Takanori Miki, Masaki Ueno, Tomomi Kuwahara, Ryuichi Shimono

Journal of pediatric surgery, 54(12) 2514-2519, Dec, 2019 Peer-reviewed
Antiviral and Virucidal Activities of Umesu Phenolics on Influenza Viruses.

Ikeda K, Nishide M, Tsujimoto K, Nagashima S, Kuwahara T, Mitani T, Koyama AH

Japanese journal of infectious diseases, Aug, 2019 Peer-reviewed
An enhanced green fluorescence protein (EGFP)-based reporter assay for quantitative detection of sporulation in Clostridium perfringens SM101.

Yuki Wakabayashi, Hirofumi Nariya, Mayo Yasugi, Tomomi Kuwahara, Mahfuzur R Sarker, Masami Miyake

International journal of food microbiology, 291 144-150, Feb 16, 2019 Peer-reviewed
Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces.

Todokoro D, Eguchi H, Suzuki T, Suzuki M, Nakayama-Imaohji H, Kuwahara T, Nomura T, Tomita H, Akiyama H

Japanese journal of ophthalmology, 62(6) 699-705, Nov, 2018 Peer-reviewed
IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria.

Akira Nakajima, Alexis Vogelzang, Mikako Maruya, Michio Miyajima, Megumi Murata, Aoi Son, Tomomi Kuwahara, Tatsuaki Tsuruyama, Satoshi Yamada, Minoru Matsuura, Hiroshi Nakase, Daniel A Peterson, Sidonia Fagarasan, Keiichiro Suzuki

The Journal of experimental medicine, 215(8) 2019-2034, Aug 6, 2018 Peer-reviewed
Ethanolamine utilization supports Clostridium perfringens growth in infected tissues.

Hirofumi Yagi, Haruyuki Nakayama-Imaohji, Hirofumi Nariya, Ayano Tada, Hisashi Yamasaki, Hideyo Ugai, Miad Elahi, Tsuneko Ono, Tomomi Kuwahara

Microbial pathogenesis, 119 200-207, Jun, 2018 Peer-reviewed
L-histidine augments the oxidative damage against Gram-negative bacteria by hydrogen peroxide

Tamiko Nagao, Haruyuki Nakayama-Imaohji, Miad Elahi, Ayano Tada, Emika Toyonaga, Hisashi Yamasaki, Katsuichiro Okazaki, Hirokazu Miyoshi, Koichiro Tsuchiya, Tomomi Kuwahara

International Journal of Molecular Medicine, 41(5) 2847-2854, May 1, 2018 Peer-reviewed
Characterization of a recombinant Bacteroides fragilis sialidase expressed in Escherichia coli

Takaaki Yamamoto, Hideyo Ugai, Haruyuki Nakayama-Imaohji, Ayano Tada, Miad Elahi, Hitoshi Houchi, Tomomi Kuwahara

Anaerobe, 50 69-75, Apr 1, 2018 Peer-reviewed
L-histidine augments the oxidative damage against Gram-negative bacteria by hydrogen peroxide

Tamiko Nagao, Haruyuki Nakayama-Imaohji, Miad Etahi, Ayano Tada, Emika Toyonaga, Hisashi Yamasaki, Katsuichiro Okazaki, Hirokazu Miyoshi, Koichiro Tsuchiya, Tomomi Kuwahara

International Journal of Molecular Medicine, Vol.41(No.5) 2847-2854, Feb 7, 2018 Peer-reviewed
D‑Tagatose inhibits the growth and biofilm formation of Streptococcus mutans.

Khaleque Hasibul, Haruyuki Nakayama-Imaohji, Masahito Hashimoto, Hisashi Yamasaki, Takaaki Ogawa, Junpei Waki, Ayano Tada, Saori Yoneda, Masaaki Tokuda, Minoru Miyake, Tomomi Kuwahara

Molecular medicine reports, 17(1) 843-851, Jan, 2018 Peer-reviewed

Misc.

次世代シークエンス技術を用いた周術期の眼表面菌叢解析

堀田芙美香, 江口洋, 桑原知巳, 今大路治之, 日下俊次

日本眼科学会雑誌, 123(臨増) 225-225, Mar, 2019
Spore purification of mouse gut derived non-culturable bacterium

Motoo Suzuki, Haruyuki Imaohji, Tomomi Kuwahara

GENES & GENETIC SYSTEMS, 89(6) 328-328, Dec, 2014
眼科領域で分離されるCorynebacteriumの薬剤耐性化状況の全国調査

江口洋, 桑原知巳, 今大路治之

感染症学雑誌, 83(6) 732-732, Nov, 2009
眼結膜由来のコリネバクテリウムにおけるフルオロキノロン感受性

桑原知巳, 江口洋, 今大路治之

感染症学雑誌, 83(3) 317-317, May, 2009
日本人の眼表面から分離されるCorynebacteriumの薬剤耐性化状況全国調査

江口洋, 桑原知巳, 塩田洋

日本眼科学会雑誌, 113(臨増) 321-321, Mar, 2009
眼材料から分離されたコリネバクテリウムのキノロン耐性化状況全国調査第2報

江口洋, 桑原知巳, 塩田洋, 宮本龍郎

日本眼科学会雑誌, 112(臨増) 234-234, Mar, 2008
コリネバクテリウムの各種キノロン薬に対する感受性の違いとgyrA遺伝子変異との関連

香留崇, 江口洋, 桑原知己, 塩田洋, 宮本龍郎

日本眼科学会雑誌, 112(臨増) 283-283, Mar, 2008
Suppressive Effect of Clostridium perfringens-produced Heat-stable Substance(s) on Proliferation of Human Colon Adenocarcinoma HT29 Cells in Culture

21(2) 66-66, Apr 1, 2007
Bacteroides fragilis のDNA逆位による外膜 vesicle 形成の制御

今大路治之, 弘田克彦, 三宅洋一郎, 桑原知巳

日本細菌学雑誌, 62(1) 135-135, Feb 25, 2007
キノロン耐性Corynebacteriumによる前眼部感染症の5例 gyrA遺伝子におけるアミノ酸配列とLVFX耐性との関連

土ヶ内健史, 江口洋, 塩田洋, 宮本龍郎, 桑原知巳

眼科臨床医報, 100(6) 461-461, Jun, 2006
眼科臨床分離株Corynebacteriumのキノロン耐性とgyrA遺伝子におけるアミノ酸配列変化

江口洋, 宮本龍郎, 土ヶ内健史, 塩田洋, 桑原知巳

日本眼科学会雑誌, 110(臨増) 156-156, Mar, 2006
Inhibitory effect of lactoferrin-producing Bacteroides uniformis cells on the initiation stage of colon carcinogenesis induced by azoxymethane in rats

ARIMOCHI Hideki, CHEWONARIN Teera, KUWAHARA Tomomi, KATAOKA Keiko, OHNISHI Yoshinari

(29) 144-144, 2000
Inhibitory effects of lemon grass components on formation of 2-amino-1-methyl-6-phenylimidazo[4, 5-b] pyridine-induced aberrant crypt foci in the rat colon

KATAOKA Keiko, TANTIWAT Thita, ARIMOCHI Hideki, VINITKETKUMNUEN Usanee, KUWAHARA Tomomi, OHNISHI Yoshinari

(29) 127-127, 2000
Antimutagenicity and inhibitory effects of bitter melon, a Thai medicinal plant, on formation of azoxymethane-induced aberrant crypt foci in the rat colon

KATAOKA Keiko, CHAMPANICHAYAKUL Sawitree, ARIMOCHI Hideki, KUWAHARA Tomomi, THUMVIJIT Somsakul, VINITKETKUMNUEN Usanee, OHNISHI Yoshinari

(28) 112-112, 1999

Books and Other Publications

感染と生体防御

建帛社, 2012 (ISBN: 9784767904467)
シンプル微生物学

南江堂, 2011 (ISBN: 9784524262076)

Presentations

腸管内における宿主微生物間相互作用に関わる分子の検索

第86回日本細菌学会総会、ワークショップ「細菌間および細菌宿主間の相互作用」, 2013
Bacteroides thetaiotaomicronにおけるマリナートランスポゾン挿入変異ライブラリーの開発

第35回日本分子生物学会年会, 2012
腸管内常在菌によるClostridium difficileの病原性抑制機構

第35回日本分子生物学会年会, 2012

Professional Memberships

Works

新規塩素系殺菌剤の開発と実用化に関する研究

2011 - 2012

Profile Information

Research Interests

Research Areas

Research History

Education

Awards

Papers

Misc.

Books and Other Publications

Presentations

Professional Memberships

Works

Research Projects

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