東智仁 (Higashi Tomohito) - マイポータル

基本情報

The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts

Yukako Oda, Taichi Sugawara, Yuko Fukata, Yasushi Izumi, Tetsuhisa Otani, Tomohito Higashi, Masaki Fukata, Mikio Furuse

Journal of Biological Chemistry 2020年2月20日査読有り
Tricellular junctions: how to build junctions at the TRICkiest points of epithelial cells

Tomohito Higashi, Ann L. Miller

MOLECULAR BIOLOGY OF THE CELL 28(15) 2023 - 2034 2017年7月査読有り
Maintenance of the Epithelial Barrier and Remodeling of Cell-Cell Junctions during Cytokinesis

Tomohito Higashi, Torey R. Arnold, Rachel E. Stephenson, Kayla M. Dinshaw, Ann L. Miller

CURRENT BIOLOGY 26(14) 1829 - 1842 2016年7月査読有り
MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells

Elaina B. Breznau, Ansley C. Semack, Tomohito Higashi, Ann L. Miller

MOLECULAR BIOLOGY OF THE CELL 26(13) 2439 - 2455 2015年7月査読有り
Deficiency of Angulin-2/ILDR1, a Tricellular Tight Junction-Associated Membrane Protein, Causes Deafness with Cochlear Hair Cell Degeneration in Mice

Tomohito Higashi, Tatsuya Katsuno, Shin-ichiro Kitajiri, Mikio Furuse

PLOS ONE 10(3) e0120674 2015年3月査読有り

Analysis of the angulin family consisting of LSR, ILDR1 and ILDR2: tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

T. Higashi, S. Tokuda, S-I. Kitajiri, H. Nakamura, Y. Oda, M. Furuse

MOLECULAR BIOLOGY OF THE CELL 23 2012年
The structure of tight junctions in brain endothelial cells

Mikio Furuse, Noriko Iwamoto, Yukako Oda, Tomohito Higashi

日本神経科学学会 2012年
ILDR1 and ILDR2 recruit Tricellulin to tricellular tight junctions.

T. Higashi, M. Furuse

MOLECULAR BIOLOGY OF THE CELL 22 2011年
Flightless-I (Fli-I) Regulates the Actin Assembly Activity of Diaphanous-related Formins (DRFs) Daam1 and mDia1 in Cooperation with Active Rho GTPase

Tomohito Higashi, Tomoyuki Ikeda, Takaaki Murakami, Ryutaro Shirakawa, Mitsunori Kawato, Katsuya Okawa, Mikio Furuse, Takeshi Kimura, Toru Kita, Hisanori Horiuchi

JOURNAL OF BIOLOGICAL CHEMISTRY 285(21) 16231 - 16238 2010年5月
BIOCHEMICAL CHARACTERIZATION OF THE EFFECTOR MOLECULES OF SMALL GTPASE RHO IN PLATELETS

T. Ikeda, H. Horiuchi, T. Higashi, R. Shirakawa, M. Kawato, T. Kita

ATHEROSCLEROSIS SUPPLEMENTS 9(1) 67 - 67 2008年5月