2014年6月
Discharge-Rate Persistence of Baseline Activity During Fixation Reflects Maintenance of Memory-Period Activity in the Macaque Posterior Parietal Cortex
CEREBRAL CORTEX
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- 巻
- 24
- 号
- 6
- 開始ページ
- 1671
- 終了ページ
- 1685
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1093/cercor/bht031
- 出版者・発行元
- OXFORD UNIV PRESS INC
Recent evidence has demonstrated that spatiotemporal patterns of spontaneous activity reflect the patterns of activity evoked by sensory stimuli. However, few studies have examined whether response profiles of task-evoked activity, which is not related to external sensory stimuli but rather to internal processes, are also reflected in those of spontaneous activity. To address this, we recorded activity of neurons in the lateral intraparietal area (LIP) when monkeys performed reaction-time and delayed-response visual-search tasks. We particularly focused on the target location-dependent modulation of delay-period activity (delay-period modulation) in the delayed-response task, and the discharge-rate persistency in fixation-period activity (baseline-activity maintenance) in the reaction-time task. Baseline-activity maintenance was assessed by the correlation between the spike counts of 2 separate bins. We found that baseline-activity maintenance, calculated from bins separated by a long interval (200-500 ms), was correlated with delay-period modulation, whereas that calculated from bins separated by a short interval (similar to 100 ms) was correlated with trial-to-trial fluctuations in baseline activity, suggesting a link between the capability to hold task-related information in delay-period activity and the degree of baseline-activity maintenance in a timescale-dependent manner.
- リンク情報
- ID情報
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- DOI : 10.1093/cercor/bht031
- ISSN : 1047-3211
- eISSN : 1460-2199
- Web of Science ID : WOS:000336529700023