YABE Tomio

J-GLOBAL         Last updated: Jul 2, 2019 at 02:42
 
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Name
YABE Tomio
Affiliation
Gifu University
Section
Faculty of Applied Biological Sciences Food Science,The Food and Life Science program
Degree
Doctor(Agriculture)(Tohoku University), Master(Agriculture)(Tohoku University)
Research funding number
70356260

Profile

Functional analysis for structure-specific glycosaminoglycan/Structural analysis of heparan sulfate on cell surface through cell stimulation/Functional Analysis for Polysaccharidesof Foodsas A Physiologically Active Substance/Study of polysaccharides of food in the relationship between physiological activity and the structure/A physiologically active substance from vegetables/Identification of collagenase inhibitor from vegetables/A physiologically active substance from sesame seeds/Identification of novel physiological function from sesame seeds

Research Areas

 

Academic & Professional Experience

 
Apr 2016
   
 
Professor, Faculty of Applied Biological Sciences, Gifu University
 
Apr 2007
 - 
Mar 2016
Associate Professor, Faculty of Applied Biological Sciences, Gifu University
 
Oct 2004
 - 
Mar 2007
Assistant Professor, Faculty of Applied Biological Sciences, Gifu University
 
Mar 2002
 - 
Sep 2004
Postdoctoral Fellow, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Institute
 
Jun 1999
 - 
May 2001
Long-Term Fellow, MIT, Human Frontier Science Program
 
1999
   
 
Fellow. Japan Soc.for the Promotion of Sci.
 
1999
 - 
2001
Long-term Fellow. Human Frontier Science Program
 
2001
 - 
2002
Postdoctral Fellow. Massachusetts Institute of Technology
 
2002
 - 
2004
Postdoctral Fellow. Tokyo Metropolitan Institute for Neurosciense
 
2004
   
 
- Research Associate. Faculty of Applied Biological Science, Gifu University
 
Apr 1999
 - 
May 1999
Research Fellow (PD), Tohoku University, Research Fellow of the Japan Society for the Promotion of Science
 
Jun 1999
 - 
Feb 2002
Postdoctoral Fellow, Department of Chemistry, Massachusetts Institute of Technology
 
Jan 1995
 - 
Feb 1998
Resident, Department of Mycology, Nippon Roche Research Center
 
Aug 1999
 - 
Sep 2000
Visiting Researcher, Harvard Medical School, Harvard University
 
Oct 2000
 - 
Feb 2002
Postdoctoral Fellow, Department of Biology, Massachusetts Institute of Technology
 
Apr 1996
 - 
Mar 1999
Research Fellow (DC1), Tohoku University, Research Fellow of the Japan Society for the Promotion of Science
 

Education

 
 
 - 
1999
Agricultural Chemistry, Graduate School, Division of Agriculture, Tohoku University
 
 
 - 
1994
Agricultural Chemistry, Faculty of Agriculture, Tohoku University
 
Apr 1990
 - 
Mar 1994
Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku University
 
Apr 1994
 - 
Mar 1996
Department of Agricultural Chemistry, Graduate School of Agriculture, Tohoku University
 
Apr 1996
 - 
Mar 1999
Department of Agricultural Chemistry, Graduate School of Agriculture, Tohoku University
 

Awards & Honors

 
Jun 1999
"Study of Heparan Sulfate Biosysnthesis", HFSP Long-Term Fellowships Award, International Human Frontier Science Program Organization
 

Published Papers

 
Ishisono, K., Yabe, T., and Kitaguchi, K.
J. Nutr. Biochem.   50 38-45   Dec 2017   [Refereed]
Matsuoka, T., Kawashima, T., Nakamura, T., and Yabe, T.
Biosci. Biotechnol. Biochem.   81(7) 1401-1404   Jul 2017   [Refereed]
Tahoun, A., Masutani, H., El-sharkawy, H., Gillespie, T., Honda, R.P., Kuwata, K., Inagaki, M., Yabe, T., Nomura, I., and Suzuki, T.
Gut Pathog.   9(27)    May 2017   [Refereed]
Inagaki, M., Kawai, S., Xijier, Fukuoka, M., Yabe, T., Iwamoto, S., and Kanamaru, Y.
Biomed. Res.   38(1) 53-59   Jan 2017   [Refereed]
Ben Othman, S., Katsuno, N., Kitayama, A., Fujimura, M., Kitaguchi, K., and Yabe, T.
Nutr. Res.   36(10) 1130-1139   Oct 2016   [Refereed]
Ben Othman, S., Katsuno, N., Kitayama, A., Fujimura, M., Kitaguchi, K., and Yabe, T.
Free Radic. Res.   50(9) 949-958   Sep 2016   [Refereed]
Yamagishi, M., Hosoda-Yabe, R., Tamai, T., Konishi, M., Imamura, A., Ishida, H., Yabe, T., Ando, A., Kiso, M.
Mar. Drugs   13(12) 7250-7274   Dec 2015   [Refereed]
Katsuno, N., Sakamoto, C., Yabe, T., Yamauchi, R., Nishizu, T., and Kato, K.
Food Sci. Tech. Res.   21(6) 787-791   Dec 2015   [Refereed]
Ben Othman, S., Katsuno, N., Kanamaru, Y., and Yabe, T.
Food Chem.   175 306-314   May 2015   [Refereed]
Nishida, M., Murata, K., Oshima, K., Itoh, C., Kitaguchi, K., Kanamaru, Y., and Yabe, T.
Glycoconj. J.   32(3-4) 153-159   Apr 2015   [Refereed]
Yabe, T., Hosoda-Yabe, R., Sakai, H., Kanamaru, Y., and Kiso, M.
Anal. Biochem.   472 1-6   Mar 2015   [Refereed]
Matsuoka, T., Takasaki, A., Mishima, T., Kawashima, T., Kanamaru, Y., Nakamura, T., and Yabe, T.
Apidologie   46(2) 167-176   Mar 2015   [Refereed]
Inagaki, M., Muranishi, H., Yamada, K., Kakehi, K., Uchida, K., Suzuki, T., Yabe, T., Nakagomi, T., Nakagomi, O. and Kanamaru, Y.
J. Dairy Sci.   97(5) 2653-2661   May 2014   [Refereed]
Nishida, M., Kozakai, T., Nagami, K., Kanamaru, Y., and Yabe, T.
Biosci. Biotechnol. Biochem.   78(5) 770-779   May 2014   [Refereed]
Nishida, M., Murata, K., Kanamaru, Y., and Yabe, T.
Biosci. Biotechnol. Biochem.   78(4) 635-643   Apr 2014   [Refereed]
Hara, Y., Mizukawa, H., Yamamoto, H., Ikami, T., Kato, K., and Yabe, T.
Biosci. Biotechnol. Biochem.   77(10) 2137-2139   Oct 2013   [Refereed]
Cairangzhuoma, Yamamoto, M., Xijier, Inagaki, M., Uchida, K., Yamashita, K., Saito, S., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   77(5) 992-997   May 2013   [Refereed]
Cairangzhuoma, Yamamoto, M., Muranishi, H., Inagaki, M., Uchida, K., Yamashita, K., Saito, S., Yabe, T., and Kanamaru, Y.
J. Dairy Sci.   96(3) 1347-1355   Mar 2013   [Refereed]
Inagaki, M., Yamamoto, M., Cairangzhuoma, Xijier, Yabe, T., Uchida, K., Kawasaki, M., Nakagomi, T., Nakagomi, O., Minamoto, N., and Kanamaru, Y.
J. Dairy Sci.   96(2) 806-814   Feb 2013   [Refereed]
A histochemicalanalysisof heparan sulfate localizationin a small intestine of mouse.
Yabe, T. and Fujitani, Y.
Bulletin of Shubun University   4(1) 11-2012   Dec 2012   [Refereed]
Shiokawa, M., Kanamaru, Y., Yabe, T., and Aoki, T.
Milk Science   61(3) 199-204   Nov 2012   [Refereed]
Effect of lactose crystallization on the change in the viscosity of concentrated skim milk at low temperature.
Shiokawa, M., Kanamaru,Y., Yabe, T., and Aoki, T.
Milchwissenschaft.   67 351-354   Nov 2012   [Refereed]
Matsuoka, T., Kawashima, T., Nakamura, T., Kanamaru, Y., and Yabe, T.
Apidologie   43(6) 685-697   Nov 2012   [Refereed]
Xijier, Mori, Y., Fukuoka, M., Cairangzhoma, Inagaki, M., Iwamoto, S., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   76(4) 843-846   Mar 2012   [Refereed]
Xijier, Inagaki, M., Kishita, K., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   75(10) 2059-2062   Oct 2011   [Refereed]
Yabe, T., Hosoda-Yabe, R., Kanamaru, Y., andKiso, M.
J. Biol. Chem.   286(14) 12397-12406   Apr 2011   [Refereed]
Tamai, H., Ando, H., Tanaka, H., Hosoda-Yabe, R., Yabe, T., Ishida, H., and Kiso, M.
Angew. Chem. Int. Edit.   50(10) 2330-2333   Mar 2011   [Refereed]
Fitriyanto, N. A., Nakamura, M., Muto, S., Kato, K., Yabe, T., Iwama, T., Kawai, K., and Pertiwiningrum, A.
J. Biosci. Bioeng.   111(2) 146-152   Feb 2011   [Refereed]
Fukaya, S., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   74(10) 2141-2144   Dec 2010   [Refereed]
Inagaki, M., Nakaya, S., Nohara,D., Yabe, T., Kanamaru,Y., and Suzuki, T.
Biosci. Biotechnol. Biochem.   74(2) 447-450   Oct 2010   [Refereed]
Inagaki, M., Nagai, S., Yabe, T., Nagaoka, S., Minamoto, N., Takahashi, T., Matsuda, T., Nakagomi, O., Nakagomi, T., Ebina, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   74(7) 1386-1390   Oct 2010   [Refereed]
Fukaya, S., Shinoda, C., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   74(10) 2127-2129   Oct 2010   [Refereed]
Inagaki, M., Yamamoto, M., Xijier, CairangZhuoMa, Uchida, K., Yamaguchi, H., Kawasaki, M.,Yamashita, K., Yabe, T., and Kanamaru, Y.
Biosci. Biotechnol. Biochem.   74(3) 680-682   Oct 2010   [Refereed]
Ogiso, Y., Hosoda-Yabe, R., Kawamoto, Y., Kawamoto, T., Kato, K., and Yabe, T.
Biosci. Biotechnol. Biochem.   72(12) 3297-3300   Dec 2008   [Refereed]
Yoshikawa, T., Kato, Y., Yuki, N., Yabe, T., Ishida, H., and Kiso, M.
Glycoconj. J.   25(6) 545-553   Aug 2008   [Refereed]
Lawrence, R., Yabe, T., HajMohammadi, S., Rhodes, J.,McNeely,M., Liu, J., Lamperti, E. D., Toselli, P. A., Lech, M., Spear, P. G., Rosenberg, R. D., and Shworak, N. W.
Matrix Biol.   26(6) 442-455   Jul 2007   [Refereed]
Takenaka, N., Iwamoto, S., Yabe, T., Yamauchi, R., Ogata, K., and Kato, K.
Colloids Surf B Biointerfaces   55(2) 131-137   Apr 2007   [Refereed]
Effect of oil on the adhesion of dehulled-roased sesame seeds
Takenaka, N., Ogata, K., Yabe, T., Yamauchi, R., and Kato, K.
13th WorldCongress of Food Science&Technology Proceeding   973-974   Sep 2006   [Refereed]
Development of novel assay system for evaluation of physiologyically active substances
Yabe, T., Nishida, M., Hosoda-Yabe, R., and Kato, K.
13th World Congress of Food Science&Technology Proceeding   1077-1078   Sep 2006   [Refereed]
Takenaka, N., Ogata, K., Yabe,T., Yamauchi, R., and Kato, K.
J. Food Sci.   71(6) 303-307   Aug 2006   [Refereed]
Yabe, T., Hata, T., He, J., and Maeda, N.
Glycobiology   15(10) 982-993   Oct 2005   [Refereed]
Maeda, N., He, J., Yajima, Y., Mikami, T., Sugahara, K., and Yabe, T.
J. Biol. Chem.   278(37) 35805-35811   Sep 2003   [Refereed]
Wu, Z. L., Zhang, L., Yabe,T., Kuberan, B., Beeler, D. L., Love, A., and Rosenberg, R. D.
J. Biol. Chem.   278(19) 17121-17129   May 2003   [Refereed]
Furukawa, K., Katsuno, Y., Urao, T., Yabe, T., Yamada-Okabe, T., Yamada-Okabe, H., Yamagata, Y., Abe, K., and Nakajima, T.
Appl. Envir. Microbiol.   68(11) 5304-5310   Nov 2002   [Refereed]
Yabe, T., Shukla, D., Spear, P. G., Rosenberg, R. D., Seeberger, P. H., and Shworak, N. W.
Biochem. J.   359(1) 235-241   Oct 2001   [Refereed]
Suzuki, K., Yabe, T., Maruyama, Y., Abe, K., and Nakajima, T.
Biosci. Biotechnol. Biochem.   65(6) 1310-1314   Jun 2001   [Refereed]
The yeast Chs4 protein stimulates the trypsin-sensitive activity of chitin synthase 4 through an apparent protein-protein nteraction.
Ono, N., Yabe, T., Sudoh, M., Nakajima, T., Yamada-Okabe, T., Arisawa, M., Yamada-Okabe, H.
Microbiology   146(2) 385-391   Feb 2000   [Refereed]
Yabe, T., Yamada-Okabe, T., Nakajima, T., Sudoh, M., Arisawa, M., and Yamada-Okabe, H.
Eur. J. Biochem.   258(3) 941-947   Dec 1998   [Refereed]
Mio, T., Yabe, T., Arisawa, M., and Yamada-Okabe, H.
J. Biol. Chem.   273(23) 14392-14397   Jun 1998   [Refereed]
Cloning of the Candida albicans Homolog of Saccharomyces cerevisiae GSC1/FKS1and its involvement in beta-1,4-glucan synthesis.
Mio, T., Adachi-Shimizu, M., Tachibana, Y., Tabuchi, H., Inoue, S. B., Yabe, T., Yamada-Okabe, T., Arisawa, M., Watanabe, T., and Yamada-Okabe, H.
J. Bacteriol.   179(13) 4096-4105   Jul 1997   [Refereed]
Isolation of the Candida albicans homologs ofSaccharomyces cerevisiae KRE6 and SKN2: Expression and physiological function.
Mio, T., Yamada-Okabe, T., Yabe, T., Nakajima, T., Arisawa, M., and Yamada-Okabe, H.
Journalof Bacteriology   179(7) 2363-2372   Apr 1997   [Refereed]
Role of three chitin synthase genes in the growth of Candida albicans.
Mio, T., Yabe, T., Sudoh, M., Satoh, Y., Nakajima, T., Arisawa, M., and Yamada-Okabe, H.
Journalof Bacteriology   178(8) 2416-2419   Apr 1996   [Refereed]
HKR2 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae.
Yabe, T., Yamada-Okabe, T., Kasahara, S., Furuichi, Y., Nakajima, T., Ichishima, E., Arisawa, M., and Yamada-Okabe, H.
Journal of Bacteriology   178(2) 477-483   Jan 1996   [Refereed]
Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-2 killer toxin, which inhibits beta-glucan synthesis.
Kasahara, S., Yamada, H., Mio, T., Shiratori, Y., Miyamoto, C., Yabe, T., Nakajima, T., Ichishima, E., and Furuichi, Y.
Journal of Bacteriology   176(5) 1488-1499   Mar 1994   [Refereed]

Misc

 
New understanding of pectin as a bioactive dietary fiber: a review
YABE Tomio
J. Food Bioact.   3 95-100   Sep 2018   [Refereed]
Yabe, T.
Kagaku to Seibutsu   54(4) 232-232   Apr 2016   [Refereed][Invited]
Use of hydrogen peroxide and peroxyl radicals to induce oxidative stress in neuronal cells
Sana Ben Othman and Tomio Yabe
Reviews in Agricultural Science   3 40-45   Oct 2015   [Refereed]
The novel physiological functions of pectin as a dietary fiber
Yabe, T.
Foods&Food Ingredients J. Jpn.   220(2) 139-146   Jun 2015   [Invited]
Glycosaminoglycans for milk
Yabe, T.
Nyugyo Gijutsu   62 62-72   Dec 2012   [Invited]
Yabe, T.
Chemistry&Education   60(10) 418-421   Oct 2012   [Refereed][Invited]
Development of the peptides that recognize glycosaminoglycans structure-specifically through phage display technique.
Yabe, T.
Seikagaku   84(4) 295-300   Apr 2012   [Refereed][Invited]
Dynamics of crude fats, free amino acids and sugars during ripening of chili pepper.
Ichiyanagi, Y., Yabe, T., Kato, K., Kohmoto, Y., and Kohmoto, T.
New Food Industry   49(4) 1-4   Apr 2007   [Refereed][Invited]

Books etc

 
新版 基礎食品学(遠藤泰志・池田郁男編著)
Dec 2015   ISBN:978-4-87492-333-7
The potential of cow’s milk proteins for prophylaxis against intestinal infection., In “Whey proteins: Functional properties, production and health benefits“, ed. Michelle Wyatt
Inagaki, M., Yabe, T. and Kanamaru, Y. (Part:Joint Work, 163-177)
NOVA Science Publishers   Jan 2015   ISBN:978-1-63463-116-7
Histochemical analysis of heparan sulfate 3-O-sulfotransferase expression in mouse brain., In “Glycosaminoglycans: Chemistry and Biology, Methods in Molecular Biology”, vol. 1229, eds. K. Balagurunathan, H. Nakato, and U. R. Desai
Yabe, T. and Maeda, N. (Part:Joint Work, 377-387)
Springer   Jan 2015   ISBN:978-1-4939-1713-6
Production and functional properties of dairy products containing lactophorin and lactadherin. In “Food Additive” ed. Yehia El-Samragy
Inagaki, M., Xijier, Nakamura, Y., Takahashi, T., Yabe, T., Nakagomi, T., Nakagomi, O., and Kanamaru, Y. (Part:Joint Work, 49-64)
InTech, Rijeka, Croatia   Apr 2012   ISBN:978-953-51-0067-6
Heparan sulfate D-glucosaminyl 3-O-sulfotransferases., In “Glycobiology Research Trends”, eds. George Powell and Olivier McCabe
YABE, T. and MAEDA, N. (Part:Joint Work, 109-126)
NOVA Science Publishers   Sep 2009   ISBN:978-1606928417
Heparan sulfate sulfotransferases., In “Neural proteoglycans”, ed. Nobuaki Maeda
YABE, T. (Part:Joint Work, 85-101)
Research Signpost   May 2007   ISBN:81-308-0143-4

Conference Activities & Talks

 
Pectin induces proliferation of intestinal cells through the alteration of cell-surface heparan sulfate [Invited]
YABE Tomio
ISNFF2017 The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods   25 Oct 2017   ISNFF
Pectin from Prunus domestica L. induces proliferation of intestinal cells through the alteration of cell-surface heparan sulfate on differentiated epithelial cells in vitro
Tomio Yabe, Mitsutaka Nishida, Toshinari Kuwae, Mayu Miyamoto, Natsumi Yamane, and Kohji Kitaguchi
1st Food Chemistry Conference   Oct 2016   Food Chemistry
Physiological function of the dietary fiber for intestinal epithelial cells in human [Invited]
Yabe, T.
the 4th UGSAS-GU International Symposium 2015   Aug 2015   UGSAS-GU
Pectin alters sulfated structure of cell-surface heparan sulfate in differentiated Caco-2 cells thereby inducing proliferation of IEC-6 cells in co-culture
Yabe T, Nishida M, Murata K, Oshima K, Kitaguchi K, KanamaruY
Gordon Research Conference 2014 Proteoglycans   Jul 2014   GRC
A specific structurein the pectin from prune recognizes fibronectin and affects on the expression level of polyamines in Caco-2 cells
Yabe T, Itoh C, Honda A, Ishikawa M, Nakamura A, Yamamoto H, Ikami T, and Kanamaru Y
EPNOE 2013 Polysaccharide Conference   Oct 2013   EPNOE
Developing a novel detection system for glycosaminoglycans using by photo-reactive probe
Yabe T, Hosoda-Yabe R, Sakai H, Kanamaru Y, and Kiso M
International Proteoglycan Meeting   Aug 2013   International Proteoglycan Committe
Developmental and regional expression of heparan sulfate sulfotransferases in the mouse brain
Yabe Tomio(TMIN),Hata Toshihiro(TMIn),He Jue(TMIN),Maeda Nobuaki(TMIN)
Sep 2004   

Research Grants & Projects

 
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2017
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2015 - Mar 2016
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2013 - Mar 2014
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2012 - Mar 2013
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2011 - 2013    Investigator(s): Tomio YABE
We found that intestinal epithelial cells recognized a pectic polysaccharide through the fibronectin located around tight junctions and altered sulfated structure of heparan sulfate on the cell surface through integrin. These findings show that fu...
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2011 - Mar 2012
Functional control by expression of proteoglycan
Project Year: 2007   
Structure of heparan sulfate
Grants and Funding
Project Year: 1999   
Analysis of Polysaccharide structure from food
Funded Research