小久保利雄 (Toshio Kokubo) - 論文

Subacute Ingestion of Caffeine and Oolong Tea Increases Fat Oxidation without Affecting Energy Expenditure and Sleep Architecture: A Randomized, Placebo-Controlled, Double-Blinded Cross-Over Trial

Zhang, Simeng, Takano, Jiro, Murayama, Norihito, Tominaga, Morie, Abe, Takashi, Park, Insung, Seol, Jaehoon, Ishihara, Asuka, Tanaka, Yoshiaki, Yajima, Katsuhiko, Suzuki, Yoko, Suzuki, Chihiro, Fukusumi, Shoji, Yanagisawa, Masashi, Kokubo, Toshio, Tokuyama, Kumpei

Nutrients 12(12) 2020年11月査読有り

DIFFERENT EFFECTS OF OREXIN RECEPTOR ANTAGONIST AND GABA(A) AGONIST ON PHYSICAL AND COGNITIVE FUNCTIONS AFTER FORCED AWAKENING

Seol, J, Fujii, Y, Park, I, Yoko, S, Kawana, F, Yajima, K, Fukusumi, S, Okura, T, Satoh, M, Tokuyama, K, Kokubo, T, Yanagisawa, M

SLEEP MEDICINE 64(1) S343 - S343 2019年12月査読有り

Improvement of slow wave sleep continuity by mattress with better body pressure dispersal.

Kokubo, Toshio, Kayaba, M, Ogata, H, Park, I, Ishihara, A, Kawana, F, Fukusumi, S, Hayashi, M, Tokuyama, K, Yanagisawa, M, Satoh, M

Sleep Medicine Research 10(2) 75 - 82 2019年12月査読有り

Distinct effects of orexin receptor antagonist and GABA agonist on sleep and physical/cognitive functions after forced awakening

Seol, Jaehoon, Fujii, Yuya, Park, Insung, Suzuki, Yoko, Kawana, Fusae, Yajima, Katsuhiko, Fukusumi, Shoji, Okura, Tomohiro, Satoh, Makoto, Tokuyama, Kumpei, Kokubo, Toshio, Yanagisawa, Masashi

Proceedings of the National Academy of Sciences of the United States of America 116(48) 24353 - 24358 2019年11月査読有り

Fc engineering of anti-Nectin-2 antibody improved thrombocytopenic adverse event in monkey

Oshima, Tsutomu, Miyashita, Hideaki, Ishimura, Yoshimasa, Ito, Yuki, Tanaka, Yoko, Hori, Akira, Kokubo, Toshio, Kurokawa, Tomofumi

PLOS ONE 13(5) 2018年5月査読有り

Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers

Oshima, Tsutomu, Sato, Shuji, Kato, Junichi, Ito, Yuki, Watanabe, Takahiro, Tsuji, Isamu, Hori, Akira, Kurokawa, Tomofumi, Kokubo, Toshio

Molecular cancer 12 60 2013年6月12日査読有り

A novel Syk kinase-selective inhibitor blocks antigen presentation of immune complexes in dendritic cells

Nakashima, Kosuke, Kokubo, Toshio, Shichijo, Michitaka, Li, Ying-Fu, Yura, Takeshi, Yamamoto, Noriyuki

European journal of pharmacology 505(1-3) 223 - 228 2004年11月28日査読有り

Inhibition of syk activity and degranulation of human mast cells by flavonoids

Shichijo, Michitaka, Yamamoto, Noriyuki, Tsujishita, Hideki, Kimata, Masahiro, Nagai, Hiroichi, Kokubo, Toshio

Biological & pharmaceutical bulletin 26(12) 1685 - 1690 2003年12月1日査読有り

The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents

Yamamoto, Noriyuki, Takeshita, Keisuke, Shichijo, Michitaka, Kokubo, Toshio, Sato, Masako, Nakashima, Kosuke, Ishimori, Mina, Nagai, Hiroichi, Li, Ying-Fu, Yura, Takeshi, Bacon, Kevin B

The Journal of pharmacology and experimental therapeutics 306(3) 1174 - 1181 2003年9月1日査読有り

Establishment of the superoxide production assay with human monocytic cell line, U937, for the evaluation of Syk kinase inhibitors

Yamamoto, Noriyuki, Shichijo, Michitaka, Kokubo, Toshio

Journal of immunological methods 268(2) 123 - 130 2002年10月査読有り

Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR

Ishibashi, O, Inui, T, Mori, Y, Kurokawa, T, Kokubo, T, Kumegawa, M

Calcified tissue international 68(2) 109 - 116 2001年2月査読有り

Cytokine requirement for the development of rat dendritic cells by in vitro culturing of bone marrow cells

Hua, Y, Miyagi, T, Saito, H, Gold, D P, Li, X K, Fujino, M, Taga, T, Amemiya, H, Suzuki, S, Kokubo, T, Kimura, H

Transplantation proceedings 32(7) 2078 - 2079 2000年11月1日

Microchimerism and allograft acceptance: is it caused by microchimerism or graft antigens?

Kimura, H, Hua, Y, Goto, T, Kokubo, T, Amemiya, H, Suzuki, S, Miyamoto, M, Tanaka, K

Transplantation proceedings 32(7) 2045 - 2046 2000年11月1日

New immunosuppressive reagent, FTY 720, spares immunologic memory

Lei, G, Amemiya, H, Suzuki, S, Goto, T, Kokubo, T, Miyamoto, M, Kimura, H

Transplantation proceedings 32(7) 1628 2000年11月1日

Directed evolution to improve the thermostability of prolyl endopeptidase

Uchiyama, H, Inaoka, T, Ohkuma-Soyejima, T, Togame, H, Shibanaka, Y, Yoshimoto, T, Kokubo, T

Journal of biochemistry 128(3) 441 - 447 2000年9月査読有り

Analysis of a local fitness landscape with a model of the rough Mt. Fuji-type landscape: application to prolyl endopeptidase and thermolysin

Aita, T, Uchiyama, H, Inaoka, T, Nakajima, M, Kokubo, T, Husimi, Y

Biopolymers 54(1) 64 - 79 2000年7月査読有り

Matrix metalloproteinases and lysosomal cysteine proteases in osteoclasts contribute to bone resorption through distinct modes of action

Inui, T, Ishibashi, O, Origane, Y, Fujimori, K, Kokubo, T, Nakajima, M

Biochemical and biophysical research communications 258(1) 173 - 178 1999年4月査読有り

Conformational studies on the specific cleavage site of Type I collagen (alpha-1) fragment (157-192) by cathepsins K and L by proton NMR spectroscopy

Nosaka, A Y, Kanaori, K, Teno, N, Togame, H, Inaoka, T, Takai, M, Kokubo, T

Bioorganic & medicinal chemistry 7(2) 375 - 379 1999年2月査読有り

The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma

Littlewood-Evans, A J, Bilbe, G, Bowler, W B, Farley, D, Wlodarski, B, Kokubo, T, Inaoka, T, Sloane, J, Evans, D B, Gallagher, J A

Cancer research 57(23) 5386 - 5390 1997年12月査読有り

Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption

Inui, T, Ishibashi, O, Inaoka, T, Origane, Y, Kumegawa, M, Kokubo, T, Yamamura, T

The Journal of biological chemistry 272(13) 8109 - 8112 1997年3月査読有り