論文

査読有り
2007年

Synchronous and asynchronous bursting states: role of intrinsic neural dynamics.

J. Comput. Neurosci.
  • Takashi Takekawa
  • ,
  • Toshio Aoyagi
  • ,
  • Tomoki Fukai

23
2
開始ページ
189
終了ページ
200
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10827-007-0027-9
出版者・発行元
SPRINGER

Brain signals such as local field potentials often display gamma-band oscillations (30-70 Hz) in a variety of cognitive tasks. These oscillatory activities possibly reflect synchronization of cell assemblies that are engaged in a cognitive function. A type of pyramidal neurons, i.e., chattering neurons, show fast rhythmic bursting (FRB) in the gamma frequency range, and may play an active role in generating the gamma-band oscillations in the cerebral cortex. Our previous phase response analyses have revealed that the synchronization between the coupled bursting neurons significantly depends on the bursting mode that is defined as the number of spikes in each burst. Namely, a network of neurons bursting through a Ca2+-dependent mechanism exhibited sharp transitions between synchronous and asynchronous firing states when the neurons exchanged the bursting mode between singlet, doublet and so on. However, whether a broad class of bursting neuron models commonly show such a network behavior remains unclear. Here, we analyze the mechanism underlying this network behavior using a mathematically tractable neuron model. Then we extend our results to a multi-compartment version of the NaP current-based neuron model and prove a similar tight relationship between the bursting mode changes and the network state changes in this model. Thus, the synchronization behavior couples tightly to the bursting mode in a wide class of networks of bursting neurons. © Springer Science+Business Media, LLC 2007.

リンク情報
DOI
https://doi.org/10.1007/s10827-007-0027-9
DBLP
https://dblp.uni-trier.de/rec/journals/jcns/TakekawaAF07
J-GLOBAL
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902229975267490
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/17387606
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000248941600003&DestApp=WOS_CPL
URL
https://www.wikidata.org/entity/Q48227955
URL
https://dblp.uni-trier.de/db/journals/jcns/jcns23.html#TakekawaAF07
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34548213585&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=34548213585&origin=inward
ID情報
  • DOI : 10.1007/s10827-007-0027-9
  • ISSN : 0929-5313
  • eISSN : 1573-6873
  • DBLP ID : journals/jcns/TakekawaAF07
  • J-Global ID : 200902229975267490
  • PubMed ID : 17387606
  • SCOPUS ID : 34548213585
  • Web of Science ID : WOS:000248941600003

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