2018年2月1日
Enhancement of cytotoxic T lymphocytes (CTLs) infiltration into the cancer tissues
Japanese Journal of Cancer and Chemotherapy
- ,
- ,
- 巻
- 45
- 号
- 2
- 開始ページ
- 227
- 終了ページ
- 231
- 記述言語
- 日本語
- 掲載種別
- 研究論文(学術雑誌)
- 出版者・発行元
- Japanese Journal of Cancer and Chemotherapy Publishers Inc.
Recently, with the rapid development of elucidating the tumor immunological status, it has become clear that various lymphocytes, which are infiltrating tumor, are deeply involved in not only tumor growth but also its elimination. The interest and importance of cytotoxic T cells (CTLs) for cancer immunotherapy has been further increased, since CTLs play an important role in eliminating cancer cells by having high cytotoxic activity and high proliferation ability. To achieve potent antitumor effects, in addition to the anti-tumor immune response induced by various methods such as cancer peptide vaccine and immune checkpoint inhibitor, it is thought to be essential that CTLs should migrate and invade into localized cancer tissues. In this article, we will introduce the latest immunotherapies related to CTLs infiltration, and various methods to enhancement of CTLs infiltration into the cancer tissues.
- リンク情報
- ID情報
-
- ISSN : 0385-0684
- PubMed ID : 29483410
- SCOPUS ID : 85045878138