Takashi Nakano

Profile Information

Affiliation: Professor, Department of Microbiology and Infection Control, Division of Preventive and Social Medicine, Faculty of Medicine, Osaka Medical and Pharmaceutical University
: (Concurrent)Director, Medical Education Center, Faculty of Medicine
: (Concurrent)Infection Control Doctor, Hospital, Infection Control Center

Degree: M.D., Ph.D.(Osama Medical College)

J-GLOBAL ID: 200901091839303720
researchmap Member ID: 1000171191

External link: https://www.osaka-med.ac.jp/~micro/

Research Interests

Research Areas

Committee Memberships

Papers

Morphological analysis for two types of viral particles in vacuoles of SARS-CoV-2-infected cells

Hong Wu, Yoshihiko Fujioka, Shoichi Sakaguchi, Youichi Suzuki, Takashi Nakano

Medical Molecular Morphology, Feb 23, 2024
Kaposi's Sarcoma-Associated Herpesvirus ORF67.5 Functions as a Component of the Terminase Complex.

Yuki Iwaisako, Tadashi Watanabe, Youichi Suzuki, Takashi Nakano, Masahiro Fujimuro

Journal of virology, 97(6) e0047523, Jun 5, 2023
Characterization of Oral Microbiota Following Chemotherapy in Patients With Hematopoietic Malignancies.

Michi Omori, Nahoko Kato-Kogoe, Shoichi Sakaguchi, Eri Komori, Kazuya Inoue, Kayoko Yamamoto, Wataru Hamada, Tomoyoshi Hayase, Tomoyuki Tano, Shota Nakamura …

Integrative cancer therapies, 22 15347354231159309-15347354231159309, 2023
Identification of the corticotropin-releasing factor receptor 1 antagonists as inhibitors of Chikungunya virus replication using a Gaussia luciferase-expressing subgenomic replicon.

Yasuo Watanabe, Youichi Suzuki, Akino Emi, Takeshi Murakawa, Takayuki Hishiki, Fumihiro Kato, Shoichi Sakaguchi, Hong Wu, Takato Yano, Chang-Kweng Lim …

Biochemical and biophysical research communications, 637 181-188, Nov 9, 2022
Salivary Microbiota Associated with Peripheral Microvascular Endothelial Dysfunction.

Nahoko Kato-Kogoe, Kuniyasu Kamiya, Shoichi Sakaguchi, Michi Omori, Eri Komori, Asako Kudo, Shota Nakamura, Takashi Nakano, Takaaki Ueno, Junko Tamaki …

Journal of atherosclerosis and thrombosis, Sep 22, 2022
The Contribution of Kaposi's Sarcoma-Associated Herpesvirus ORF7 and Its Zinc-Finger Motif to Viral Genome Cleavage and Capsid Formation.

Yuki Iwaisako, Tadashi Watanabe, Manami Futo, Rimiko Okabe, Yuichi Sekine, Youichi Suzuki, Takashi Nakano, Masahiro Fujimuro

Journal of virology, 96(18) e0068422, Sep 8, 2022
NeoRdRp: A Comprehensive Dataset for Identifying RNA-dependent RNA Polymerases of Various RNA Viruses from Metatranscriptomic Data.

Shoichi Sakaguchi, Syun-Ichi Urayama, Yoshihiro Takaki, Kensuke Hirosuna, Hong Wu, Youichi Suzuki, Takuro Nunoura, Takashi Nakano, So Nakagawa

Microbes and environments, 37(3), Aug 24, 2022 Peer-reviewed
Comparison of the gastric microbiome in Billroth I and Roux-en-Y reconstructions after distal gastrectomy

Yoshiro Imai, Sang-Woong Lee, Shoichi Sakaguchi, Nahoko Kato-Kogoe, Kohei Taniguchi, Michi Omori, Ryo Tanaka, Kotaro Honda, Wataru Osumi, Takashi Nakano …

Scientific Reports, 12(10594) 10594-10594, Jun, 2022 Peer-reviewed
幽門側胃切除術後のBillroth I法再建とRoux-en-Y再建後の胃液による胃内細菌叢の比較

今井義朗, 李相雄, 田中亮, 本田浩太郎, 坂口翔一, 小越菜保子, 谷口高平, 大森実知, 中野隆史, 植野高章 …

日本外科学会定期学術集会抄録集, 122回 SF-8, Apr, 2022
First isolation and genomic characterization of bovine parechovirus from faecal samples of cattle in Japan.

Mami Oba, Shoichi Sakaguchi, Hong Wu, Yoshihiko Fujioka, Hitoshi Takemae, Hisako Oki, Megumi Kawai, Mai Shiokawa, Hiroshi Aoki, Yuka Fukase …

The Journal of general virology, 103(2), Feb, 2022
Human hepatitis B virus-derived virus-like particle as a drug and DNA delivery carrier.

Chiho Sakai, Kohei Hosokawa, Tadashi Watanabe, Youichi Suzuki, Takashi Nakano, Keiji Ueda, Masahiro Fujimuro

Biochemical and biophysical research communications, 581 103-109, Dec 3, 2021
Three-dimensional reconstruction by electron tomography for the application to ultrastructural analysis of SARS-CoV-2 particles.

Hong Wu, Yoshihiko Fujioka, Shoichi Sakaguchi, Youichi Suzuki, Takashi Nakano

Medical molecular morphology, 55(1) 60-67, Nov 26, 2021
大阪府北摂地域のマダニにおけるダニ媒介性フレボウイルスDabieshan Tick Virusの調査

任聿輝, 坂口翔一, 伊藤直司, 大林直輝, 呉紅, 鈴木陽一, 中野隆史

日本獣医学会学術集会講演要旨集, 164回 [DVO-15], Sep, 2021
Strong alkaline electrolyzed water efficiently inactivates SARS-CoV-2, other viruses, and Gram-negative bacteria.

Youichi Suzuki, Takayuki Hishiki, Akino Emi, Shoichi Sakaguchi, Ronko Itamura, Rain Yamamoto, Tamio Matsuzawa, Kunitada Shimotohno, Masashi Mizokami, Takashi Nakano …

Biochemical and biophysical research communications, 575 36-41, Aug 23, 2021
Evaluation of SARS-CoV-2 RNA quantification by RT-LAMP compared to RT-qPCR.

Kenta Minami, Ryota Masutani, Youichi Suzuki, Meri Kubota, Naofumi Osaka, Toyofumi Nakanishi, Takashi Nakano, Akira Ukimura

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 27(7) 1068-1071, Jul, 2021
Characterization of salivary microbiota in elderly patients with type 2 diabetes mellitus: a matched case-control study.

Michi Omori, Nahoko Kato-Kogoe, Shoichi Sakaguchi, Kuniyasu Kamiya, Nozomu Fukui, Yan-Hong Gu, Shota Nakamura, Takashi Nakano, Masaaki Hoshiga, Akihisa Imagawa …

Clinical oral investigations, 26(1) 493-504, Jun 18, 2021
Kaposi's sarcoma-associated herpesvirus ORF17 plays a key role in capsid maturation.

Sayaka Tsurumi, Tadashi Watanabe, Yuki Iwaisako, Youichi Suzuki, Takashi Nakano, Masahiro Fujimuro

Virology, 558 76-85, Jun, 2021
COVID-19に対する感染防御は,どれほど院内感染を抑制しうるのか

川西史子, 南健太, 柴田有理子, 鈴木陽一, 中野隆史, 浮村聡

感染症学雑誌, 95(臨増) 264-264, Apr, 2021
Characterization of Salivary Microbiota in Patients with Atherosclerotic Cardiovascular Disease: A Case-Control Study.

Nahoko Kato-Kogoe, Shoichi Sakaguchi, Kuniyasu Kamiya, Michi Omori, Yan-Hong Gu, Yuri Ito, Shota Nakamura, Takashi Nakano, Junko Tamaki, Takaaki Ueno …

Journal of atherosclerosis and thrombosis, 29(3) 403-421, Feb 19, 2021
Construction and characterization of an infectious clone generated from Chikungunya virus SL11131 strain.

Youichi Suzuki, Atsushi Tanaka, Yusuke Maeda, Akino Emi, Yoshihiko Fujioka, Shoichi Sakaguchi, Subhash G Vasudevan, Takeshi Kobayashi, Chang-Kweng Lim, Tomohiko Takasaki …

Virology, 552 52-62, Jan 2, 2021

Misc.

KSHV ORF7・ORF29・ORF67.5はターミナーゼ複合体として機能する

祝迫佑紀, 渡部匡史, 鈴木陽一, 中野隆史, 藤室雅弘

次世代を担う若手のためのファーマ・バイオフォーラム講演要旨集, 22nd, 2023
Functional analysis of KSHV terminase complex components

祝迫佑紀, 渡部匡史, 鈴木陽一, 中野隆史, 藤室雅弘

日本ウイルス学会学術集会プログラム・予稿集(Web), 70th, 2023
KSHV ORF7・ORF29・ORF67.5はターミナーゼ複合体機能に重要である

祝迫佑紀, 渡部匡史, 鈴木陽一, 中野隆史, 藤室雅弘

微生物シンポジウム講演要旨集, 35th, 2023
B型肝炎ウイルスを模した肝臓を標的とする薬物・遺伝子送達キャリアの開発

酒井智帆, 細川晃平, 大川浩史, 渡部匡史, 関根勇一, 中野隆史, 鈴木陽一, 上田啓次, 藤室雅弘

日本薬学会年会要旨集, 141年会 29P01-259S, Mar, 2021
Characterization of Salivary Microbiota in Patients With Atherosclerosis and Its Potential as a Biomarker

Masaaki Hoshiga, Nahoko Kato-Kogoe, Shoichi Sakaguchi, Kuniyasu Kamiya, Michi Omori, Akemi Nitta, Yanhong Gu, Keisuke Fukui, Yuri Ito, Takashi Nakano …

CIRCULATION, 140, Nov, 2019
カポジ肉腫関連ヘルペスウイルスがコードするORF17のプロテアーゼ活性は、ウイルス成熟カプシド形成に必須である

鶴見さやか, 渡部匡史, 鈴木陽一, 中野隆史, 藤室雅弘

日本薬学会年会要旨集, 139年会(3) 54-54, Mar, 2019
ATP-association to intrabacterial nanotransportation system in Vibrio cholerae (vol 48, pg 225, 2015)

Yuji Matsuzaki, Hong Wu, Takashi Nakano, Takashi Nakahari, Kouichi Sano

MEDICAL MOLECULAR MORPHOLOGY, 48(4) 239-240, Dec, 2015
Regulation of hepatitis C virus secretion by the Hrs-dependent exosomal pathway

Keiichi Tamai, Masaaki Shiina, Nobuyuki Tanaka, Takashi Nakano, Akitsugu Yamamoto, Yasuteru Kondo, Eiji Kakazu, Jun Inoue, Koji Fukushima, Kouichi Sano …

VIROLOGY, 422(2) 377-385, Jan, 2012 Peer-reviewed
Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein

Keiichi Tamai, Nobuyuki Tanaka, Takashi Nakano, Eiji Kakazu, Yasuteru Kondo, Jun Inoue, Masaaki Shiina, Koji Fukushima, Tomoaki Hoshino, Kouichi Sano …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 399(3) 384-390, Aug, 2010
Evaluation of an electrolysis apparatus for inactivating antineoplastics in clinical wastewater

Toyohide Kobayashi, Jun Hirose, Kouichi Sano, Naoki Hiro, Yoshio Ijiri, Hiroya Takiuchi, Hiroshi Tamai, Hiroshi Takenaka, Kazuhiko Tanaka, Takashi Nakano

CHEMOSPHERE, 72(4) 659-665, Jun, 2008
Viral titers in the sera of Dengue Fever Patients among passengers at the Quarantine station of Kansai International Airport.

Ooi, Y, Hayashi, A, Aoki, H, Eda, J, Hamada, M, Imura, S, Nakano, T, Sano, K, Kashiwagi, E

Japn. J. Infect. Diseases, 61(4) 329-330, 2008
Epidemiological evidence of multidrug-resistant Shigella sonnei colonization in India by sentinel surveillance in a Japanese quarantine station

Y. Arai, T. Nakano

The Journal of the Japanese Association for Infectious Diseases (Kansensyogaku-zassi), 82(4) 322-327, 2008
Suppression of alpha smooth muscle actin expression by IFN-gamma in established myofibroblast cell lines

Kazunari Tanaka, Kouichi Sano, Takashi Nakano, Kazuhide Yuba, Mitsuo Kinoshita

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 27(10) 835-839, Oct, 2007
30-C1-09-4 抗悪性腫瘍剤を含む医療廃液の新規不活性化処理装置の評価(がん薬物療法,社会の期待に応える医療薬学を)

小林豊英, 廣瀬潤, 佐野浩一, 広直樹, 玉井浩, 竹中洋, 中野隆史

日本医療薬学会年会講演要旨集, 17 212-212, Sep 1, 2007
H. pylori による胃上皮樹立細胞の細胞変性効果

岩倉研二, 呉紅, 中野隆史, 大黒恵理子, 佐野浩一

日本細菌学雑誌, 62(1) 99-99, Feb 25, 2007
外国における薬剤耐性赤痢菌の分布について

新井康泰, 青木宏明, 中野隆史, 佐野浩一

日本細菌学雑誌, 62(1) 185-185, Feb 25, 2007
Establishment of gold standard for electrolyzed sodium chloride solution in disinfection.

Yokoyama, I, Nakano, T, Morita, C, Arai, Y, Hirayama, T, Aoki, H, Hirose, J, Sano, K

Bull.Osaka Med. Col., 53 11-19, 2007
Unique Enhancement of Multinuclear Giant Cell Formation in AGS Cell Line Infected with Helicobacter pylori.

Iwakura, K, Wu, H, Nakano, T, Daikoku, E, Shimamoto, C, Katsu, K, Sano, K

Bull.Osaka Med. Col., 53 1-9, 2007
Prostaglandin E-2 release in gastric antral mucosa of guinea-pigs: basal PGE(2) release by cyclo-oxygenase 2 and ACh-stimulated PGE(2) release by cyclo-oxygenase 1

Chikao Shimamoto, Yoshihiko Nakanishi, Ken-ichi Katsu, Takashi Nakano, Takahiro Kubota, Hiroshi Mori, Takashi Nakahari

EXPERIMENTAL PHYSIOLOGY, 91(6) 1015-1024, Nov, 2006
The restriction fragment length polymorphism patterns and the presence of outer membrane protein gene in some Vibrio cholerae O1 and O139 strains.

Zin,NM, Nakano, T, Sano, K

J.Sci.Tech.Tropics, 2 17-20, 2006

Books and Other Publications

微生物学・感染症学

中野, 隆史 (Role: Editor)

南江堂, Nov, 2020 (ISBN: 9784524237982)
医療・福祉系学生のための専門基礎科目（改訂第２版）

中野隆史

金芳堂, 2013
動物由来感染症マニュアル

中野隆史 (Role: Joint author, 破傷風・ボツリヌス症・ガス壊疽・他)

金芳堂, 2009
医療従事者のためのこれだけは知っておきたい６１の法律

中野隆史 (Role: Joint author, 感染症法)

金芳堂, 2007
医療・福祉系学生のための専門基礎科目

中野隆史 (Role: Joint author, 微生物学)

金芳堂, 2007
イメージできる臨床微生物学・医動物学

中野隆史 (Role: Editor, 全章)

メディカ出版, 2006
病原微生物学

中野隆史 (Role: Joint author, 肝炎ウイルス)

東京化学同人, 2002

Teaching Experience

Professional Memberships

Research Projects

Studies on the mechanism of oral microbiome formation via microbiome analysis of pregnant women and their infants

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
電気分解の医療応用

その他の研究制度, 2006 - 2013
Application of Electrolysis to Medical Fields

Cooperative Research, 2003 - 2013
Development and evaluation of a novel method for inactivation of clinical wastewater based on electrolysis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

NAKANO Takashi, KOHNO Takehiro, WU Hong
病原細菌が保有する逆転写酵素に関する研究

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2002 - 2004

佐野浩一, 中野隆史, 河野武弘
Helicobacter pylori の病原因子に関する研究

共同研究, 2000
Pathogenic agents of Helicobacter pylori

2000
非放射性逆転写酵素活性測定法の開発とその応用
Basic and Clinical applicatian of PCR to HIV infection
Development and application of non-radioisotopic reverse transcriptase assay

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