1993年6月
CYTOTOXIC SESQUITERPENES FROM NARDOSTACHYS-CHINENSIS
CHEMICAL & PHARMACEUTICAL BULLETIN
- ,
- ,
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- 巻
- 41
- 号
- 6
- 開始ページ
- 1183
- 終了ページ
- 1184
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1248/cpb.41.1183
- 出版者・発行元
- PHARMACEUTICAL SOC JAPAN
Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.
- リンク情報
- ID情報
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- DOI : 10.1248/cpb.41.1183
- ISSN : 0009-2363
- CiNii Articles ID : 130003772907
- identifiers.cinii_nr_id : 9000254237308
- Web of Science ID : WOS:A1993LH56400035