Minamikawa MF, Nonaka K, Kaminuma E, Kajiya-Kanegae H, Onogi A, Goto S, Yoshioka T, Imai A, Hamada H, Hayashi T, Matsumoto S, Katayose Y, Toyoda A, Fujiyama A, Nakamura Y, Shimizu T, Iwata H
Akter A, Ooka T, Gotoh Y, Yamamoto S, Fujita H, Terasoma F, Kida K, Taira M, Nakadouzono F, Gokuden M, Hirano M, Miyashiro M, Inari K, Shimazu Y, Tabara K, Toyoda A, Yoshimura D, Itoh T, Kitano T, Sato MP, Katsura K, Mondal SI, Ogura Y, Ando S, Hayashi T
Genome biology and evolution 9(1) 124-133 2017年1月 [査読有り]
Hoshino A, Jayakumar V, Nitasaka E, Toyoda A, Noguchi H, Itoh T, Shin-I T, Minakuchi Y, Koda Y, Nagano AJ, Yasugi M, Honjo MN, Kudoh H, Seki M, Kamiya A, Shiraki T, Carninci P, Asamizu E, Nishide H, Tanaka S, Park KI, Morita Y, Yokoyama K, Uchiyama I, Tanaka Y, Tabata S, Shinozaki K, Hayashizaki Y, Kohara Y, Suzuki Y, Sugano S, Fujiyama A, Iida S, Sakakibara Y
Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS
Hamaji T, Mogi Y, Ferris PJ, Mori T, Miyagishima S, Kabeya Y, Nishimura Y, Toyoda A, Noguchi H, Fujiyama A, Olson BJ, Marriage TN, Nishii I, Umen JG, Nozaki H
Hanschen ER, Marriage TN, Ferris PJ, Hamaji T, Toyoda A, Fujiyama A, Neme R, Noguchi H, Minakuchi Y, Suzuki M, Kawai-Toyooka H, Smith DR, Sparks H, Anderson J, Bakarić R, Luria V, Karger A, Kirschner MW, Durand PM, Michod RE, Nozaki H, Olson BJ
Junichi Watanabe, Masahira Hattori, Matthew Berriman, Michael J. Lehane, Neil Hall, Neil Hall, Philippe Solano, Serap Aksoy, Winston Hide, Winston Hide, Yeya Touré, Geoffrey M. Attardo, Alistair C. Darby, Atsushi Toyoda, Christiane Hertz-Fowler, Denis M. Larkin, James A. Cotton, Mandy J. Sanders, Martin T. Swain, Michael A. Quail, Noboru Inoue, Sophie Ravel, Todd D. Taylor, Tulika P. Srivastava, Tulika P. Srivastava, Vineet Sharma, Vineet Sharma, Wesley Warren, Richard K. Wilson, Yutaka Suzuki, Daniel Lawson, Daniel S.T. Hughes, Karyn Megy, Daniel K. Masiga, Paul O. Mireji, Immo A. Hansen, Jan Van Den Abbeele, Joshua B. Benoit, Joshua B. Benoit, Kostas Bourtzis, Kostas Bourtzis, Kostas Bourtzis, George F.O. Obiero, George F.O. Obiero, Hugh M. Robertson, Jeffery W. Jones, Jing Jiang Zhou, Linda M. Field, Markus Friedrich, Steven R.G. Nyanjom, Erich L. Telleria, Guy Caljon, José M.C. Ribeiro, Alvaro Acosta-Serrano, Alvaro Acosta-Serrano, Cher Pheng Ooi, Clair Rose, David P. Price, Lee R. Haines, Alan Christoffels, Cheolho Sim, Daphne Q.D. Pham, David L. Denlinger, Dawn L. Geiser, Irene A. Omedo, Joy J. Winzerling, Justin T. Peyton, Kevin K. Marucha, Mario Jonas, Megan E. Meuti, Neil D. Rawlings, Qirui Zhang, Rosaline W. Macharia, Rosaline W. Macharia, Veronika Michalkova, Veronika Michalkova, Zahra Jalali Sefid Dashti, Aaron A. Baumann, Gerd Gäde, Heather G. Marco, Jelle Caers, Liliane Schoofs, Michael A. Riehle, Wanqi Hu, Zhijian Tu, Aaron M. Tarone, Anna R. Malacrida, Caleb K. Kibet, Francesca Scolari, Jacobus J.O. Koekemoer, Jacobus J.O. Koekemoer, Judith Willis, Ludvik M. Gomulski, Marco Falchetto, Maxwell J. Scott, Shuhua Fu, Sing Hoi Sze, Thiago Luiz, Brian Weiss, Deirdre P. Walshe
Science 344(6182) 380-386 2014年1月
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vec...
Gamete fusion or fertilization is one of the most important steps in sexual reproduction. HAP2/GCS1 is a potential gamete membrane fusion component. We analyzed whole genome sequences of two strains with opposite mating types (mt- and mt+) in the ...
Yuji Takahashi, Yoko Fukuda, Jun Yoshimura, Atsushi Toyoda, Kari Kurppa, Kari Kurppa, Hiroyoko Moritoyo, Veronique V. Belzil, Patrick A. Dion, Patrick A. Dion, Koichiro Higasa, Koichiro Doi, Hiroyuki Ishiura, Jun Mitsui, Hidetoshi Date, Budrul Ahsan, Takashi Matsukawa, Yaeko Ichikawa, Takashi Moritoyo, Mayumi Ikoma, Tsukasa Hashimoto, Fumiharu Kimura, Shigeo Murayama, Osamu Onodera, Masatoyo Nishizawa, Mari Yoshida, Naoki Atsuta, Gen Sobue, Ja Cals, Jennifer A. Fifita, Jennifer A. Fifita, Jennifer A. Fifita, Kelly L. Williams, Kelly L. Williams, Kelly L. Williams, Ian P. Blair, Ian P. Blair, Ian P. Blair, Garth A. Nicholson, Garth A. Nicholson, Paloma Gonzalez-Perez, Robert H. Brown, Masahiro Nomoto, Klaus Elenius, Klaus Elenius, Guy A. Rouleau, Guy A. Rouleau, Guy A. Rouleau, Asao Fujiyama, Shinichi Morishita, Jun Goto, Shoji Tsuji, Shoji Tsuji
American Journal of Human Genetics 93(5) 900-905 2013年11月
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by the degeneration of motor neurons and typically results in death within 3-5 years from onset. Familial ALS (FALS) comprises 5%-10% of ALS cases, and the id...
Commonly used classical inbred mouse strains have mosaic genomes with sequences from different subspecific origins. Their genomes are derived predominantly from the Western European subspecies Mus musculus domesticus, with the remaining sequences ...
Completion of tomato genome sequencing project has broad impacts on genetic and genomic studies of tomato and Solanaceae plants. The reference genome sequence derived from Solanum lycopersicum cv 'Heinz 1706' serves as the firm basis for sequencin...
Kyoko Hayashida, Yuichiro Hara, Takashi Abe, C. Y. Chisato Yamasaki, Atsushi Toyoda, Takehide Kosuge, Yutaka Suzuki, Yoshiharu Sato, Shuichi Kawashima, Toshiaki Katayama, Hiroyuki Wakaguri, N. I. Noboru Inoue, K. H. Keiichi Homma, Masahito Tada-Umezaki, Yukio Yagi, Y. F. Yasuyuki Fujii, T. H. Takuya Habara, Minoru Kanehisa, H. W. Hidemi Watanabe, Kimihito Ito, Takashi Gojobori, Takashi Gojobori, H. S. Hideaki Sugawara, Tadashi Imanishi, William Weir, Malcolm Gardner, A. P. Arnab Pain, Brian Shiels, Masahira Hattori, Vishvanath Nene, Chihiro Sugimoto
mBio 3(5) 2012年11月
We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T. parva and...
In order to upgrade the genome sequence information of J. curcas L., we integrated de novo assembly of a total of 537 million paired-end reads generated from the Illumina sequencing platform into the current genome assembly which was obtained by a...
Marilyn B. Renfree, Marilyn B. Renfree, Anthony T. Papenfuss, Anthony T. Papenfuss, Anthony T. Papenfuss, Janine E. Deakin, Janine E. Deakin, James Lindsay, Thomas Heider, Katherine Belov, Katherine Belov, Willem Rens, Paul D. Waters, Paul D. Waters, Elizabeth A. Pharo, Geoff Shaw, Geoff Shaw, Emily S.W. Wong, Emily S.W. Wong, Christophe M. Lefèvre, Kevin R. Nicholas, Yoko Kuroki, Matthew J. Wakefield, Matthew J. Wakefield, Kyall R. Zenger, Kyall R. Zenger, Kyall R. Zenger, Chenwei Wang, Chenwei Wang, Malcolm Ferguson-Smith, Frank W. Nicholas, Danielle Hickford, Danielle Hickford, Hongshi Yu, Hongshi Yu, Kirsty R. Short, Hannah V. Siddle, Hannah V. Siddle, Stephen R. Frankenberg, Stephen R. Frankenberg, Keng Y. Chew, Keng Y. Chew, Brandon R. Menzies, Brandon R. Menzies, Brandon R. Menzies, Jessica M. Stringer, Jessica M. Stringer, Shunsuke Suzuki, Shunsuke Suzuki, Timothy A. Hore, Timothy A. Hore, Margaret L. Delbridge, Margaret L. Delbridge, Hardip Patel, Hardip Patel, Amir Mohammadi, Amir Mohammadi, Nanette Y. Schneider, Nanette Y. Schneider, Nanette Y. Schneider, Yanqiu Hu, Yanqiu Hu, William O'Hara, Shafagh Al Nadaf, Shafagh Al Nadaf, Chen Wu, Zhi Ping Feng, Zhi Ping Feng, Benjamin G. Cocks, Jianghui Wang, Paul Flicek, Stephen M.J. Searle, Susan Fairley, Kathryn Beal, Javier Herrero, Dawn M. Carone, Dawn M. Carone, Yutaka Suzuki, Sumio Sugano, Atsushi Toyoda, Yoshiyuki Sakaki, Shinji Kondo, Yuichiro Nishida, Shoji Tatsumoto, Ion Mandiou, Arthur Hsu, Arthur Hsu, Kaighin A. McColl, Benjamin Lansdell, George Weinstock, Elizabeth Kuczek, Elizabeth Kuczek, Elizabeth Kuczek, Elizabeth Kuczek, Annette McGrath, Annette McGrath, Peter Wilson, Peter Wilson, Artem Men, Artem Men
Myostatin (MSTN) functions as a negative regulator of skeletal muscle mass. In mammals, MSTN-deficient animals result in an increase of skeletal muscle mass with both hyperplasia and hypertrophy. A MSTN gene is highly conserved within the fish spe...
Spiroacetal compounds are ubiquitous in nature, and their stereospecific structures are responsible for diverse pharmaceutical activities. Elucidation of the biosynthetic mechanisms that are involved in spiroacetal formation will open the door to ...
Glycyrrhiza uralensis (Leguminosae, Fabaceae) is the most important medicinal plant used as a natural sweetener, in Chinese herbal medicines, and as a tobacco flavoring agent. Here, we report the generation of 56,857 expressed sequence tags (ESTs)...
We isolated transformation-competent artificial chromosome (TAC) clones harboring a high-molecular-weight glutenin subunit (HMW-GS) gene and a low-molecular-weight GS (LMW-GS) gene from wheat genomic DNA, and developed transgenic rice lines with t...
Ahsan B, Kobayashi D, Yamada T, Kasahara M, Sasaki S, Saito TL, Nagayasu Y, Doi K, Nakatani Y, Qu W, Jindo T, Shimada A, Naruse K, Toyoda A, Kuroki Y, Fujiyama A, Sasaki T, Shimizu A, Asakawa S, Shimizu N, Hashimoto S, Yang J, Lee Y, Matsushima K, Sugano S, Sakaizumi M, Narita T, Ohishi K, Haga S, Ohta F, Nomoto H, Nogata K, Morishita T, Endo T, Shin-I T, Takeda H, Kohara Y, Morishita S
Rensing SA, Lang D, Zimmer AD, Terry A, Salamov A, Shapiro H, Nishiyama T, Perroud PF, Lindquist EA, Kamisugi Y, Tanahashi T, Sakakibara K, Fujita T, Oishi K, Shin-I T, Kuroki Y, Toyoda A, Suzuki Y, Hashimoto S, Yamaguchi K, Sugano S, Kohara Y, Fujiyama A, Anterola A, Aoki S, Ashton N, Barbazuk WB, Barker E, Bennetzen JL, Blankenship R, Cho SH, Dutcher SK, Estelle M, Fawcett JA, Gundlach H, Hanada K, Heyl A, Hicks KA, Hughes J, Lohr M, Mayer K, Melkozernov A, Murata T, Nelson DR, Pils B, Prigge M, Reiss B, Renner T, Rombauts S, Rushton PJ, Sanderfoot A, Schween G, Shiu SH, Stueber K, Theodoulou FL, Tu H, Van de Peer Y, Verrier PJ, Waters E, Wood A, Yang L, Cove D, Cuming AC, Hasebe M, Lucas S, Mishler BD, Reski R, Grigoriev IV, Quatrano RS, Boore JL
Science (New York, N.Y.) 319(5859) 64-69 2008年1月 [査読有り]
Kasahara M, Naruse K, Sasaki S, Nakatani Y, Qu W, Ahsan B, Yamada T, Nagayasu Y, Doi K, Kasai Y, Jindo T, Kobayashi D, Shimada A, Toyoda A, Kuroki Y, Fujiyama A, Sasaki T, Shimizu A, Asakawa S, Shimizu N, Hashimoto S, Yang J, Lee Y, Matsushima K, Sugano S, Sakaizumi M, Narita T, Ohishi K, Haga S, Ohta F, Nomoto H, Nogata K, Morishita T, Endo T, Shin-I T, Takeda H, Morishita S, Kohara Y
J. Ohashi, J. Ohashi, I. Naka, A. Toyoda, M. Takasu, K. Tokunaga, T. Ishida, Y. Sakaki, H. Hohjoh, H. Hohjoh
Tissue Antigens 68(5) 427-431 2006年11月
To estimate the species-specific mutation rates at the DRB1 locus in humans and chimpanzee, we analyzed the nucleotide sequence of a 37.6-kb chimpanzee chromosomal segment containing the entire Patr-DRB1*0701 allele and the flanking nongenic regio...
H. A. Vu, H. A. Vu, P. T. Xinh, P. T. Xinh, M. Masuda, T. Motoji, A. Toyoda, Y. Sakaki, K. Tokunaga, Y. Sato
Leukemia 20(8) 1414-1421 2006年8月
The FMS-like tyrosine kinase 3 (FLT3) gene, belonging to the receptor tyrosine kinase (TK) subclass III family, plays an important role in normal hematopoiesis and is one of the most frequently mutated genes in hematologic malignancies as well as ...
Aruga J, Kamiya A, Takahashi H, Fujimi TJ, Shimizu Y, Ohkawa K, Yazawa S, Umesono Y, Noguchi H, Shimizu T, Saitou N, Mikoshiba K, Sakaki Y, Agata K, Toyoda A
Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y
Kuroki Y, Toyoda A, Noguchi H, Taylor TD, Itoh T, Kim DS, Kim DW, Choi SH, Kim IC, Choi HH, Kim YS, Satta Y, Saitou N, Yamada T, Morishita S, Hattori M, Sakaki Y, Park HS, Fujiyama A
Taniguchi Y, Takeda S, Furutani-Seiki M, Kamei Y, Todo T, Sasado T, Deguchi T, Kondoh H, Mudde J, Yamazoe M, Hidaka M, Mitani H, Toyoda A, Sakaki Y, Plasterk RH, Cuppen E
Genome biology 7(12) 2006年 [査読有り]
[Comparative studies on human and chimpanzee genomes].
Sakuraba Y, Sezutsu H, Takahasi KR, Tsuchihashi K, Ichikawa R, Fujimoto N, Kaneko S, Nakai Y, Uchiyama M, Goda N, Motoi R, Ikeda A, Karashima Y, Inoue M, Kaneda H, Masuya H, Minowa O, Noguchi H, Toyoda A, Sakaki Y, Wakana S, Noda T, Shiroishi T, Gondo Y
Biochemical and biophysical research communications 336(2) 609-616 2005年10月 [査読有り]
Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Abouelleil A, Allen NR, Anderson S, Bloom T, Bugalter B, Butler J, Cook A, DeCaprio D, Engels R, Garber M, Gnirke A, Hafez N, Hall JL, Norman CH, Itoh T, Jaffe DB, Kuroki Y, Lehoczky J, Lui A, Macdonald P, Mauceli E, Mikkelsen TS, Naylor JW, Nicol R, Nguyen C, Noguchi H, O'Leary SB, O'Neill K, Piqani B, Smith CL, Talamas JA, Topham K, Totoki Y, Toyoda A, Wain HM, Young SK, Zeng Q, Zimmer AR, Fujiyama A, Hattori M, Birren BW, Sakaki Y, Lander ES
Fujiyama A, Watanabe H, Toyoda A, Taylor TD, Itoh T, Tsai SF, Park HS, Yaspo ML, Lehrach H, Chen Z, Fu G, Saitou N, Osoegawa K, de Jong PJ, Suto Y, Hattori M, Sakaki Y
Science (New York, N.Y.) 295(5552) 131-134 2002年1月 [査読有り]
Y. Ichikawa, J. Goto, M. Hattori, A. Toyoda, K. Ishii, S. Y. Jeong, H. Hashida, N. Masuda, K. Ogata, F. Kasai, M. Hirai, P. Maciel, G. A. Rouleau, Y. Sakaki, I. Kanazawa
Journal of Human Genetics 46(7) 413-422 2001年7月
Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder that is clinically characterized by cerebellar ataxia and various associated symptoms. The disease is caused by an unstable expansion of the CAG repeat in the MJD gen...
John D. McPherson, Marco Marra, Marco Marra, La Deana Hillier, Robert H. Waterston, Asif Chinwalla, John Wallis, Mandeep Sekhon, Kristine Wylie, Elaine R. Mardis, Richard K. Wilson, Robert Fulton, Tamara A. Kucaba, Caryn Wagner-McPherson, William B. Barbazuk, Simon G. Gregory, Sean J. Humphray, Lisa French, Richard S. Evans, Graeme Bethel, Adam Whittaker, Jane L. Holden, Owen T. McCann, Andrew Dunham, Carol Soderlund, Carol Soderlund, Carol E. Scott, David R. Bentley, Gregory Schuler, Hsiu Chuan Chen, Wonhee Jang, Eric D. Green, Jacquelyn R. Idol, Valerie V.Braden Maduro, Kate T. Montgomery, Eunice Lee, Ashley Miller, Suzanne Emerling, Raju Kucherlapati, Richard Gibbs, Steve Scherer, J. Harley Gorrell, Erica Sodergren, Kerstin Clerc-Blankenburg, Paul Tabor, Susan Naylor, Dawn Garcia, J. de Jong, J. de Jong, J. de Jong, Joseph J. Catanese, Joseph J. Catanese, Joseph J. Catanese, Norma Nowak, Kazutoyo Osoegawa, Kazutoyo Osoegawa, Kazutoyo Osoegawa, Shizhen Qin, Lee Rowen, Anuradha Madan, Monica Dors, Leroy Hood, Barbara Trask, Cynthia Friedman, Hillary Massa, Vivian G. Cheung, Ilan R. Kirsch, Thomas Reid, Raluca Yonescu, Jean Weissenbach, Thomas Bruls, Roland Heilig, Elbert Branscomb, Anne Olsen, Norman Doggett, Jan Fang Cheng, Trevor Hawkins, Richard M. Myers, Jin Shang, Lucia Ramirez, Jeremy Schmutz, Olivia Velasquez, Kami Dixon, Nancy E. Stone, David R. Cox, David Haussler, David Haussler, W. James Kent, Terrence Furey, Sanja Rogic, Scot Kennedy, Steven Jones, André Rosenthal, Gaiping Wen, Markus Schilhabel, Gernot Gloeckner, Gerald Nyakatura, Gerald Nyakatura, Reiner Siebert, Brigitte Schlegelberger
Nature 409(6822) 934-941 2001年2月
The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the sele...
Eric S. Lander, Lauren M. Linton, Bruce Birren, Chad Nusbaum, Michael C. Zody, Jennifer Baldwin, Keri Devon, Ken Dewar, Michael Doyle, William Fitzhugh, Roel Funke, Diane Gage, Katrina Harris, Andrew Heaford, John Howland, Lisa Kann, Jessica Lehoczky, Rosie Levine, Paul McEwan, Kevin McKernan, James Meldrim, Jill P. Mesirov, Cher Miranda, William Morris, Jerome Naylor, Christina Raymond, Mark Rosetti, Ralph Santos, Andrew Sheridan, Carrie Sougnez, Nicole Stange-Thomann, Nikola Stojanovic, Aravind Subramanian, Dudley Wyman, Jane Rogers, John Sulston, Rachael Ainscough, Stephan Beck, David Bentley, John Burton, Christopher Clee, Nigel Carter, Alan Coulson, Rebecca Deadman, Panos Deloukas, Andrew Dunham, Ian Dunham, Richard Durbin, Lisa French, Darren Grafham, Simon Gregory, Tim Hubbard, Sean Humphray, Adrienne Hunt, Matthew Jones, Christine Lloyd, Amanda McMurray, Lucy Matthews, Simon Mercer, Sarah Milne, James C. Mullikin, Andrew Mungall, Robert Plumb, Mark Ross, Ratna Shownkeen, Sarah Sims, Robert H. Waterston, Richard K. Wilson, Ladeana W. Hillier, John D. McPherson, Marco A. Marra, Elaine R. Mardis, Lucinda A. Fulton, Asif T. Chinwalla, Kymberlie H. Pepin, Warren R. Gish, Stephanie L. Chissoe, Michael C. Wendl, Kim D. Delehaunty, Tracie L. Miner, Andrew Delehaunty, Jason B. Kramer, Lisa L. Cook, Robert S. Fulton, Douglas L. Johnson, Patrick J. Minx, Sandra W. Clifton, Trevor Hawkins, Elbert Branscomb, Paul Predki, Paul Richardson, Sarah Wenning, Tom Slezak, Norman Doggett, Jan Fang Cheng, Anne Olsen, Susan Lucas, Christopher Elkin, Edward Uberbacher, Marvin Frazier
Nature 409(6822) 2001年2月
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the hum...
Medical and Pediatric Oncology 35 516-521 2000年12月
Background. We have identified for the first time a homozygously deleted region within the smallest region of overlap at 1p36.2-3 in two neuroblastoma cell lines. Procedure. The 800kb PAC contig covering the entire homozygously deleted region was ...
We have isolated and characterized a novel zinc finger gene by screening a human testis cDNA library. The isolated cDNA, termed ZNF219, contains an open reading frame of 2169 nucleotides encoding 723 amino acids. Sequence analysis revealed 9 sets ...
Loss of heterozygosity of the distal region of chromosome 1p where tumor suppressor gene(s) might harbor is frequently observed in many human cancers including neuroblastoma (NBL) with MYCN amplification and poor prognosis. We have identified for ...
M. Hattori, A. Fujiyama, T. D. Taylor, H. Watanabe, T. Yada, H. S. Park, A. Toyoda, K. Ishii, Y. Totoki, D. K. Choi, E. Soeda, M. Ohki, T. Takagi, Y. Sakaki, Y. Sakaki, S. Taudien, K. Blechschmidt, A. Polley, U. Menzel, J. Delabar, K. Kumpf, R. Lehmann, D. Patterson, K. Reichwald, A. Rump, M. Schillhabel, A. Schudy, W. Zimmermann, A. Rosenthal, J. Kudoh, K. Shibuya, K. Kawasaki, S. Asakawa, A. Shintani, T. Sasaki, K. Nagamine, S. Mitsuyama, S. E. Antonarakis, S. Minoshima, N. Shimizu, G. Nordsiek, K. Homischer, P. Brandt, M. Scharfe, O. Schön, A. Desario, J. Reichelt, G. Kauer, H. Blöcker, J. Ramser, A. Beck, S. Klages, S. Hennig, L. Riesselmann, E. Dagand, T. Haaf, S. Wehrmeyer, K. Borzym, K. Gardiner, D. Nizetic, F. Francis, H. Lehrach, R. Reinhardt, M. L. Yaspo
Nature 405(6784) 2000年5月
Chromosome 21 is the smallest human autosome. An extra copy of chromosome 21 causes Down syndrome, the most frequent genetic cause of significant mental retardation, which affects up to 1 in 700 live births. Several anonymous loci for monogenic di...
Jun Kusuda, Momoki Hirai, Atsushi Toyoda, Reiko Tanuma, Aya Nomura-Kitabayashi, Katsuyuki Hashimoto
Gene 209(1/2) 13-21 1998年3月
A sequence homologous to the transaldolase gene (TALDO) was identified in a polymorphic cosmid DNA mapped on human chromosome 11p15 by exon trapping with pSPL3. Analysis of lambda clones contiguous to the cosmid clone showed that the related gene ...
Journal of Fermentation and Bioengineering 85(5) 536-538 1998年1月
D-[1- 13 C]Glucose is useful for studies on tracing by means of 13 C- magnetic resonance imaging (MRI) the fate of a metabolite in the brain, and this technique is expected to become a sophisticated clinical tool for the diagnosis of neurological ...
Journal of Fermentation and Bioengineering 83(1) 113-115 1997年1月
13 C-labelled L-serine was efficiently produced from [ 13 C] formaldehyde and glycine by using partially purified L-serine hydroxymethyltransferase from Methylobacterium extorquens JCM 2804, tetrahydrofolate and a tetrahydrofolate regeneration sys...
We screened potential promoter regions from NotI-linking cosmid clones mapped on human chromosome Xq28 region with our constructed trapping vector and isolated six fragments containing transcription activity. Using one of the obtained fragments as...
Many eukaryote promoters, particularly those for so-called housekeeping genes, have multiple GC boxes which are the binding sites of the transcription factor, Spl. It has been proposed that Spl binds to the multiple GC boxes, and then the GC box-b...
Journal of Biological Chemistry 286(8) 6175-6183 2011年2月
Boron homeostasis is important for plants, as boron is essential but is toxic in excess. Under high boron conditions, the Arabidopsis thaliana borate transporter BOR1 is trafficked from the plasma membrane (PM) to the vacuole via the endocytic pat...
Proceedings of the National Academy of Sciences of the United States of America 107(11) 5220-5225 2010年3月
Boron (B) is essential for plant growth but is toxic when present in excess. In the roots of Arabidopsis thaliana under B limitation, a boric acid channel, NIP5;1, and a boric acid/borate exporter, BOR1, are required for efficient B uptake and sub...
Y. Kuroki, A. Toyoda, H. Noguchi, T. D. Taylor, T. Itoh, D. S. Kim, D. W. Kim, S. H. Choi, I. C. Kim, H. H. Choi, Y. S. Kim, Y. Satta, N. Saitou, T. Yamada, S. Morishita, M. Hattori, Y. Sakaki, H. S. Park, A. Fujiyama
Y. Kuroki, A. Toyoda, H. Noguchi, T. D. Taylor, T. Itoh, D. S. Kim, D. W. Kim, S. H. Choi, I. C. Kim, H. H. Choi, Y. S. Kim, Y. Satta, N. Saitou, T. Yamada, S. Morishita, M. Hattori, Y. Sakaki, H. S. Park, A. Fujiyama
Chad Nusbaum, Michael C. Zody, Mark L. Borowsky, Michael Kamal, Chinnappa D. Kodira, Todd D. Taylor, Charles A. Whittaker, Jean L. Chang, Christina A. Cuomo, Ken Dewar, Michael G. FitzGerald, Xiaoping Yang, Amr Abouelleil, Nicole R. Allen, Scott Anderson, Toby Bloom, Boris Bugalter, Jonathan Butler, April Cook, David DeCaprio, Reinhard Engels, Manuel Garber, Andreas Gnirke, Nabil Hafez, Jennifer L. Hall, Catherine Hosage Norman, Takehiko Itoh, David B. Jaffe, Yoko Kuroki, Jessica Lehoczky, Annie Lui, Pendexter Macdonald, Evan Mauceli, Tarjei S. Mikkelsen, Jerome W. Naylor, Robert Nicol, Cindy Nguyen, Hideki Noguchi, Sinéad B. O'Leary, Keith O'Neill, Bruno Piqani, Cherylyn L. Smith, Jessica A. Talamas, Kerri Topham, Yasushi Totoki, Atsushi Toyoda, Hester M. Wain, Sarah K. Young, Qiandong Zeng, Andrew R. Zimmer, Asao Fujiyama, Masahira Hattori, Bruce W. Birren, Yoshiyuki Sakaki, Eric S. Lander
Y. Sakaki, H. Watanabe, T. Taylor, M. Hattori, A. Fujiyama, A. Toyoda, Y. Kuroki, T. Itoh, N. Saitou, S. Oota, C. G. Kim, T. Kitano, H. Lehrach, M. L. Yaspo, R. Sudbrak, A. Kahla, R. Reinhardt, M. Kube, M. Platzer, S. Taenzer, P. Galgoczy, A. Kel, H. Blöecker, M. Scharfe, G. Nordsiek, I. Hellmann, I. Hellmann, P. Khaitovich, P. Khaitovich, S. Pääbo, S. Pääbo, Z. Chen, S. Y. Wang, S. X. Ren, X. L. Zhang, H. J. Zheng, G. F. Zhu, B. F. Wang, G. P. Zhao, S. F. Tsai, K. Wu, T. T. Liu, K. J. Hsiao, H. S. Park, Y. S. Lee, J. E. Cheong, S. H. Choi
Cold Spring Harbor Symposia on Quantitative Biology 68 455-460 2003年12月
Y. Sakaki, H. Watanabe, A. Fujiyama, M. Hattori, A. Toyoda, T. D. Taylor
International Congress Series 1246 183-187 2002年12月
Comparative genomics is a powerful approach to extract genetic information from large stretches of nucleotide sequences through identification of conserved regions that are most likely functionally important. Genomic information is also the most v...
M. Hattori, A. Fujiyama, T. D. Taylor, H. Watanabe, T. Yada, H. S. Park, A. Toyoda, K. Ishll, Y. Totoki, D. K. Choi, Y. Groner, E. Soeda, M. Ohki, T. Takagi, Y. Sakaki, S. Taudlen, K. Blechschmidt, A. Polley, U. Menzel, J. Delabar, K. Kumpf, R. Lehmann, D. Patterson, K. Reichwald, A. Rump, M. Schillhabel, A. Schudy, W. Zimmermann, A. Rosenthal, J. Kudoh, K. Schibuya, K. Kawasaki, S. Asakawa, A. Shintani, T. Sasaki, K. Nagamine, S. Mitsuyama, S. E. Antonarakis, S. Minoshima, N. Shimizu, G. Nordsiek, K. Hornischer, P. Brant, M. Scharfe, O. Schon, A. Desario, J. Relchelt, G. Kauer, H. Blocker, J. Ramser, A. Beck, S. Klages, S. Hennig, L. Riesselmann, E. Dagand, T. Haaf, S. Wehrmeyer, K. Borzym, K. Gardiner, D. Nizetic, F. Francis, H. Lehrach, R. Reinhardt, M. L. Yaspo
Joint porphyra genome project to reveal early development of plantsystems
Choi,D.-W., Choi, S.-H., Fujiyama, A., Hwang, M.S, Kuroki, Y., Mikami, K., Park, H.-J., Saga, N., Tabata, S., and Toyoda, A.
The Biology of Genomes, CSHL 2008年5月6日
国立遺伝学研究所以外との共同発表あり
Comparative metagenomics revealed commonly enriched gene sets in human intestine.
Kurokawa, K., Ito, T., Kuwahara, T., Oshima, K., Toh, H., Toyoda, A., Taylor, T.D., Nogucji, H., Mori, H., Kim, S.-W., Itoh, K., Morita, H., Takami, H., Sakaki, T., Hayashi, T.and Hattori, M.
The Biology of Genomes. CSHL 2008年5月6日
国立遺伝学研究所以外との共同発表あり
Comprehensive analysis of Y chromosomes toward understanding of the male-specific genome functions.
Kuroki, Y.,Toyoda, A., Tatsumoto, S., Sakaki, Y. and ,Fujiyama, A.
The Biology of Genomes. CSHL 2008年5月6日
国立遺伝学研究所以外との共同発表あり
Genome Sequencing Project of a Unicellular Choanoflagellate, Monosiga ovata: Extensive Molecular Phylogenetic Analysis with Choanoflagellate Genes Reveals Divergence Patterns of Gene Family Members in the Early Evolution of Metazoans.
Iwabe, N., Kuma, K., Katoh, K., Suga, H., Hirose, N., Toh, H., Miyata, T., Suzuki, Y., Kasahara, M., Narita, t., Shin-i, T., Kuroki, Y., Toyoda, A., Sugano, S., Morishita, S., Kohara, Y. and Fujiyama, A.
XXInternational Congress of Genetics 2008年7月12日
国立遺伝学研究所以外との共同発表あり
Comparative Analysis of Chromosome 21 Subtelomeric Regions between Human and Chimpanzee.
Kuroki, Y.,Toyoda, A.,Tatsumoto, S.,Sakaki, Y. and Fujiyama, A.
Meta-EST analysis of a symbiotic protistan community in the termite gut
Noda, S., Kurokawa, K., Tatsumoto, S., Sakaki, Y., Toyoda, A., Ohkuma, M.
The 12th International Symposium on Microbial Ecology (ISME12) 2008年8月17日
国立遺伝学研究所以外との共同発表あり
Complete genome of the uncultured "Termite Group 1" bacteria in a single host protist cell
Hongoh, Y., Sharma, V.K., Prakash, T., Toyoda, A., Hattori, M., Ohkuma, M.
The 12th International Symposium on Microbial Ecology (ISME12) 2008年8月17日
国立遺伝学研究所以外との共同発表あり
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
Watanabe, T., Totoki, Y., Toyoda, A., Kaneda, M., Miyagawa, S.,Obata, Y, Chiba, H., T. Kono, H., Kohara, Y., Nakano, T., Surani, A., Sakaki, Y.,Sasaki, H.
第３１回日本分子生物学会、第８１回日本生化学会合同大会 2008年12月9日
国立遺伝学研究所以外との共同発表あり
Effect of Hyper-parallel sequencers on comparative genomics
Fujiyama, A., Toyoda, A., Kuroki, Y., Shin-I, T., Kohara, Y.
