夏目豊彰 (Toyoaki Natsume) - 論文

CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency.

Yujiro Yoshizaki, Yunosuke Ouchi, Dicky Kurniawan, Eisuke Yumoto, Yuki Yoneyama, Faiza Ramadhani Rizqullah, Hiyori Sato, Mirjam Hanako Sarholz, Toyoaki Natsume, Masato T Kanemaki …

Scientific reports 14(1) 31904-31904 2024年12月30日査読有り

Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes.

Kayo Hibino, Yuji Sakai, Sachiko Tamura, Masatoshi Takagi, Katsuhiko Minami, Toyoaki Natsume, Masa A Shimazoe, Masato T Kanemaki, Naoko Imamoto, Kazuhiro Maeshima

Nature communications 15(1) 7152-7152 2024年8月21日査読有り

Characterizing replisome disassembly in human cells.

Rebecca M Jones, Joaquin Herrero Ruiz, Shaun Scaramuzza, Sarmi Nath, Chaoyu Liu, Marta Henklewska, Toyoaki Natsume, Robert G Bristow, Francisco Romero, Masato T Kanemaki …

iScience 27(7) 110260-110260 2024年7月19日査読有り

TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells

Shaun Scaramuzza, Rebecca M. Jones, Martina Muste Sadurni, Alicja Reynolds-Winczura, Divyasree Poovathumkadavil, Abigail Farrell, Toyoaki Natsume, Patricia Rojas, Cyntia Fernandez Cuesta, Masato T. Kanemaki …

Nature Communications 14(1) 5071-5071 2023年8月21日査読有り

Global landscape of replicative DNA polymerase usage in the human genome

Eri Koyanagi, Yoko Kakimoto, Tamiko Minamisawa, Fumiya Yoshifuji, Toyoaki Natsume, Atsushi Higashitani, Tomoo Ogi, Antony M. Carr, Masato T. Kanemaki, Yasukazu Daigaku

Nature Communications 13(1) 7221-7221 2022年11月24日査読有り

Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy.

Laura J Grange, John J Reynolds, Farid Ullah, Bertrand Isidor, Robert F Shearer, Xenia Latypova, Ryan M Baxley, Antony W Oliver, Anil Ganesh, Sophie L Cooke …

Nature communications 13(1) 6664-6664 2022年11月4日査読有り

AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells

Sundaramoorthy Revathidevi, Kazuyoshi Hosomichi, Toyoaki Natsume, Hirofumi Nakaoka, Naoko T. Fujito, Hisako Akatsuka, Takehito Sato, Arasambattu Kannan Munirajan, Ituro Inoue

International Journal of Molecular Sciences 23(19) 11124-11124 2022年9月22日査読有り

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".

Subhendu K Das, Vladislav Kuzin, Donald P Cameron, Suzanne Sanford, Rajiv Kumar Jha, Zuqin Nie, Marta Trullols Rosello, Ronald Holewinski, Thorkell Andresson, Jan Wisniewski …

Molecular cell 2021年12月6日査読有り

Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1.

Anika Wiegard, Vladislav Kuzin, Donald P Cameron, Jan Grosser, Michele Ceribelli, Rashid Mehmood, Roberto Ballarino, Francesco Valant, Radosław Grochowski, Ivana Karabogdan …

Molecular cell 2021年11月5日査読有り

Chromosome oscillation promotes Aurora A-dependent Hec1 phosphorylation and mitotic fidelity.

Kenji Iemura, Toyoaki Natsume, Kayoko Maehara, Masato T Kanemaki, Kozo Tanaka

The Journal of cell biology 220(7) 2021年7月5日査読有り

Replication timing maintains the global epigenetic state in human cells.

Kyle N Klein, Peiyao A Zhao, Xiaowen Lyu, Takayo Sasaki, Daniel A Bartlett, Amar M Singh, Ipek Tasan, Meng Zhang, Lotte P Watts, Shin-Ichiro Hiraga …

Science (New York, N.Y.) 372(6540) 371-378 2021年4月23日査読有り

MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells.

Takahiko Murayama, Yasuto Takeuchi, Kaoru Yamawaki, Toyoaki Natsume, Li Mengjiao, Rojas-Chaverra N Marcela, Tatsunori Nishimura, Yuta Kogure, Asuka Nakata, Kana Tominaga …

Cancer science 112(3) 1209-1224 2020年12月19日査読有り

The RIF1-Long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress

Lotte P Watts, Toyoaki Natsume, Yuichiro Saito, Javier Garzon, Qianqian Dong, Lora Boteva, Nick Gilbert, Masato T Kanemaki, Shin-ichiro Hiraga, Anne D Donaldson

eLife 9 2020年11月3日査読有り

Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase.

Andrés Bueno Venegas, Toyoaki Natsume, Masato Kanemaki, Ian D Hickson

Cell reports 31(3) 107533-107533 2020年4月21日査読有り

HsSAS-6-dependent cartwheel assembly ensures stabilization of centriole intermediates.

Yoshiba S, Tsuchiya Y, Ohta M, Gupta A, Shiratsuchi G, Nozaki Y, Ashikawa T, Fujiwara T, Natsume T, Kanemaki M …

Journal of cell science 132(12) 2019年6月査読有り

Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole.

Yesbolatova A, Natsume T, Hayashi KI, Kanemaki MT

Methods (San Diego, Calif.) 2019年4月査読有り

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.

Morii I, Iwabuchi Y, Mori S, Suekuni M, Natsume T, Yoshida K, Sugimoto N, Kanemaki MT, Fujita M