Tomonori Saotome - My portal - researchmap

Profile Information

Affiliation: Assistant Professor, Department of Materials Chemistry and Bioengineering, National Institute of Technology, Oyama College

Degree: Doctor of Engineering(Sep, 2019, Tokyo University of Agriculture and Technology)

J-GLOBAL ID: 201901005628545046
researchmap Member ID: B000366975

Research Interests

9

Research Areas

2

Research History

4

Apr, 2024 - Present

Assistant Professor, Department of Materials Chemistry and Bioengineering, National Institute of Technology, Oyama College
Apr, 2022 - Mar, 2024

Department of Materials Science and Bioengineering, Nagaoka University of Technology
Dec, 2020 - Mar, 2022

Assistant professor, Department of Bioengineering, Nagaoka University of Technology
Oct, 2019 - Nov, 2020

Project assistant professor, Institute of Global Innovation Research, Tokyo University of Agriculture and Technology

Education

5

Oct, 2016 - Sep, 2019

Life Science and Biotechnology, Graduate School of Engineering, PhD, Tokyo University of Agriculture and Technology
Feb, 2018 - Apr, 2018

構造生物学研究センター, フランス・モンペリエ工科大学
Apr, 2015 - Sep, 2016

Biotechnology and Life Sciences, Graduate school of engineering, MS, Tokyo University of Agriculture and Technology
Feb, 2016 - Mar, 2016

構造生物学研究センター, フランス・モンペリエ工科大学
Apr, 2011 - Mar, 2015

Department of Biotechnology and Life Science, Faculty of Engineering, Tokyo University of Agriculture and Technology

Major Papers

12

The Reversible Oligomerization (RO) of Small Globular Proteins at High-Temperature and the Inhibition of Their Amyloidogenesis

Tomonori Saotome

Netsusokutei, 50(3) 103-109, Jul, 2023 Peer-reviewedLead authorCorresponding author
Blocking PSD95‐PDZ3's amyloidogenesis through point mutations that inhibit high‐temperature reversible oligomerization (RO)

Tomonori Saotome, Sawaros Onchaiya, Brindha Subbaian, Taichi Mezaki, Satoru Unzai, Keiichi Noguchi, Jose C. Martinez, Shun‐ichi Kidokoro, Yutaka Kuroda

The FEBS Journal, 289(11) 3205-3216, Jun, 2022 Peer-reviewedLead author
Unusual Reversible Oligomerization of Unfolded Dengue Envelope Protein Domain 3 at High Temperatures and Its Abolition by a Point Mutation

Tomonori Saotome, Shigeyoshi Nakamura, Mohammad M. Islam, Akiko Nakazawa, Mariano Dellarole, Fumio Arisaka, Shun-ichi Kidokoro, Yutaka Kuroda

BIOCHEMISTRY, 55(32) 4469-4475, Aug, 2016 Peer-reviewedLead author

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Major Presentations

17

The reversible oligomerization (RO) of small globular proteins at high-temperature and the artificial suppression of their amyloidogenesis

Tomonori Saotome, Sawaros Onchaiya, Brindha Subbaian, Jose Martinez, Yutaka Kuroda, Shun-ichi Kidokoro

26th International Conference on Chemical Thermodynamics (ICCT-2023), Jul 31, 2023

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Professional Memberships

3

Oct, 2020 - Present

日本熱測定学会
Sep, 2016 - Present

日本生物物理学会
Jun, 2016 - Present

日本蛋白質科学会

Research Projects

2

食品添加物リゾチームの熱凝集抑制に向けた高温でのRO形成の物性解析

2023年度研究助成, 公共財団法人古泉財団, Apr, 2023 - Mar, 2024
The development of molecular design to inhibit the amyloid fibrillation by inhibiting the reversible oligomerization at high temperature with a single residue mutation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024