Tsuyoshi Shimamura

J-GLOBAL         Last updated: Mar 1, 2018 at 16:32
 
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Name
Tsuyoshi Shimamura
Affiliation
Hokkaido University

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Toshiya Kamiyama, Tatsuya Orimo, Kenji Wakayama, Shingo Shimada, Akihisa Nagatsu, Hideki Yokoo, Hirofumi Kamachi, Kenichiro Yamashita, Tsuyoshi Shimamura, Akinobu Taketomi
World Journal of Surgical Oncology   15    Aug 2017
© 2017 The Author(s). Background: Because hepatectomy is not recommended in patients with stage B hepatocellular carcinoma (HCC) of the Barcelona Clinic Liver Cancer (BCLC) staging, we evaluated the survival outcomes of hepatectomy for stage B in ...
Yuki Wada, Tamotsu Kamishima, Tsuyoshi Shimamura, Norio Kawamura, Kenichiro Yamashita, Kenneth Sutherland, Hiroshi Takeda
British Journal of Radiology   90    Jan 2017
© 2017 The Authors. Published by the British Institute of Radiology. Objective: To demonstrate the superiority of total psoas volume (TPV) over total psoas area (TPA) in terms of predicting post-operative complications in living-donor liver transp...
Masaaki Matsushima, Ichiro Yabe, Masaya Tsuda, Mamoru Sakakibara, Tsuyoshi Shimamura, Hidenao Sasaki
Internal Medicine   56 3231-3235   Jan 2017
© 2017 The Japanese Society of Internal Medicine. A 54-year-old man with polycystic liver disease received a domino liver transplantation (DLT) from a patient of hereditary ATTR amyloidosis with the transthyretin Ser50Arg mutation. Ten years after...
Shingo Shimada, Kenji Wakayama, Moto Fukai, Tsuyoshi Shimamura, Takahisa Ishikawa, Daisuke Fukumori, Maki Shibata, Kenichiro Yamashita, Taichi Kimura, Satoru Todo, Ikuroh Ohsawa, Akinobu Taketomi
Artificial Organs   40 1128-1136   Dec 2016
Copyright © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc. Hydrogen gas reduces ischemia and reperfusion injury (IRI) in the liver and other organs. However, the precise mechanism remains elusive. W...
Satoru Todo, Kenichiro Yamashita, Ryoichi Goto, Masaaki Zaitsu, Akihisa Nagatsu, Tetsu Oura, Masaaki Watanabe, Takeshi Aoyagi, Tomomi Suzuki, Tsuyoshi Shimamura, Toshiya Kamiyama, Norihiro Sato, Junichi Sugita, Kanako Hatanaka, Hisashi Bashuda, Sonoko Habu, Anthony J. Demetris, Ko Okumura
Hepatology   64 632-643   Aug 2016
© 2016 by the American Association for the Study of Liver Diseases Potent immunosuppressive drugs have significantly improved early patient survival after liver transplantation (LT). However, long-term results remain unsatisfactory because of adve...
M. Fukai, N. Kobayashi, T. Ishikawa, K. Wakayama, S. Shimada, K. Umemoto, S. Ohtani, M. Fujiyoshi, K. Yamashita, T. Shimamura, A. Taketomi
Transplantation Proceedings   48 1288-1291   May 2016
© 2016 Elsevier Inc. All rights reserved. Cellular survival and death are at least partially regulated by the phosphorylation of proteins. A chaperon protein, 14-3-3ζ, regulates the activity of many proteins by covering the phosphorylation site wi...
Shingo Shimada, Moto Fukai, Kenji Wakayama, Takahisa Ishikawa, Nozomi Kobayashi, Taichi Kimura, Kenichiro Yamashita, Toshiya Kamiyama, Tsuyoshi Shimamura, Akinobu Taketomi, Satoru Todo
Surgery Today   45 892-903   Nov 2015
© 2014, Springer Japan. Background and purpose: Hydrogen sulfide (H 2 S) ameliorates hepatic ischemia and reperfusion injury (IRI), but the precise mechanism remains elusive. We investigated whether sodium hydrogen sulfide (NaHS), a soluble deriva...
Yuki Inagaki, Yukio Oshiro, Tomohiro Tanaka, Tomoharu Yoshizumi, Hideaki Okajima, Kohei Ishiyama, Chikashi Nakanishi, Masaaki Hidaka, Hiroshi Wada, Taizo Hibi, Kosei Takagi, Masaki Honda, Kaori Kuramitsu, Hideaki Tanaka, Taiji Tohyama, Toshihiko Ikegami, Satoru Imura, Tsuyoshi Shimamura, Yoshimi Nakayama, Taizen Urahashi, Kazumasa Yamagishi, Hiroshi Ohnishi, Shigeo Nagashima, Masaharu Takahashi, Ken Shirabe, Norihiro Kokudo, Hiroaki Okamoto, Nobuhiro Ohkohchi
EBioMedicine   2 1607-1612   Nov 2015
© 2015 The Authors. Background: Recently, chronic hepatitis E has been increasingly reported in organ transplant recipients in European countries. In Japan, the prevalence of hepatitis E virus (HEV) infection after transplantation remains unclear,...
Masahiko Taniguchi, Tsuyoshi Shimamura, Satoru Todo, Hiroyuki Furukawa
Surgery Today   45 663-671   Jun 2015
© 2014, Springer Japan. In living-donor liver transplantation with a left lobe graft, which can reduce the burden on the donor compared to right lobe graft, the main problem is small-for-size (SFS) syndrome. SFS syndrome is a multifactorial diseas...
Tadashi Koizumi, Ken Furuya, Masaru Baba, Kuniaki Sadaoka, Chihiro Sekiya, Atsuo Hattori, Ryoichi Goto, Takeshi Aoyagi, Kenichirou Yamashita, Tsuyoshi Shimamura
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine   104 586-589   Mar 2015
Kentaro Kobayashi, Naoya Hattori, Osamu Manabe, Kenji Hirata, Keiichi Magota, Tsuyoshi Shimamura, Nagara Tamaki
Annals of Transplantation   20 51-58   Jan 2015
© 2015, Ann Transplant. Background: Living liver donation is associated with size-dependent complications. The resectable size and its safety margin should be defined for the safety of donors. The purpose of the present study was to determine if t...
Toshimi Kaido, Tsuyoshi Shimamura, Yasuhiko Sugawara, Hiroshi Sadamori, Ken Shirabe, Michio Yamamoto, Shinji Uemoto
BMJ Open   5    Jan 2015
Introduction: This multicentre randomised controlled clinical trial will aim to determine the ability of an extract (TJ-100) of Daikenchuto (traditional Japanese herbal medicine; Kampo) to prevent bowel dysfunction in at least 110 patients after l...
Toshiya Kamiyama, Hideki Yokoo, Tatsuhiko Kakisaka, Tatsuya Orimo, Kenji Wakayama, Hirofumi Kamachi, Yosuke Tsuruga, Kenichiro Yamashita, Tsuyoshi Shimamura, Satoru Todo, Akinobu Taketomi
Hepatology Research   45    Jan 2015
& Sons, Ltd. Aim: To evaluate the oncological implications of multiplication of α-fetoprotein (AFP) and protein induced by vitamin K absence or antagonists-II (PIVKA-II) in patients with hepatocellular carcinoma (HCC). Methods: Data were prospect...
Yui Ishiguro, Tsuyoshi Shimamura, Shigenori Homma, Hideki Kawamura, Norihiko Takahashi, Yasuyuki Koshizuka, Ryoichi Goto, Kenichiro Yamashita, Akinobu Taketomi, Satoru Todo
Japanese Journal of Gastroenterological Surgery   48 921-928   Jan 2015
© 2015 The Japanese Society of Gastroenterological Surgery. A 57-year-old woman underwent a living-donor liver transplantation (LT) for cirrhosis from autoimmune hepatitis. She had been receiving immunosuppressive therapy with tacrolimus and mycop...
Tetsu Oura, Tetsu Oura, Kenichiro Yamashita, Tomomi Suzuki, Tomomi Suzuki, Masaaki Watanabe, Masaaki Watanabe, Gentaro Hirokata, Kenji Wakayama, Masahiko Taniguchi, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo
Transplantation   98    Jan 2014
S. Nakahashi, H. Furukawa, T. Shimamura, S. Todo, S. Gando
Anaesthesia and Intensive Care   42 138-140   Jan 2014
M. Taniguchi, H. Furukawa, T. Kawai, H. Morikawa, K. Morozumi, M. Goto, T. Kondo, A. Aikawa, T. Ito, S. Takahara, M. Nio, N. Kokudo, S. Uemoto, N. Fukushima, K. Yoshida, T. Kenmochi, H. Date, M. Ono, S. Eguchi, T. Shimamura, K. Mizuta, T. Yoshizumi, T. Ueno
Transplantation Proceedings   46 1071-1073   Jan 2014
Introduction Multiorgan procurement is not an easy procedure and requires special technique and training. Since sufficient donors are not available for on-site training in Japan, establishment of the educational program for multiorgan procurement ...
Hiroto Egawa, Tsuyoshi Shimamura, Satoru Todo
Journal of Japanese Society of Gastroenterology   111 892-898   Jan 2014
Kenji Wakayama, Toshiya Kamiyama, Hideki Yokoo, Tatsuhiko Kakisaka, Hirofumi Kamachi, Yosuke Tsuruga, Kazuaki Nakanishi, Tsuyoshi Shimamura, Satoru Todo, Akinobu Taketomi
World Journal of Surgical Oncology   11    Oct 2013
Background: The prognosis for advanced hepatocellular carcinoma (HCC) with tumor thrombi in the inferior vena cava (IVC) or right atrium (RA) is poor, and there is no established effective treatment for this condition. Thus study aimed to evaluate...
M. Watanabe, K. Yamashita, T. Suzuki, H. Kamachi, D. Kuraya, Y. Koshizuka, M. Ogura, T. Yoshida, T. Aoyagi, D. Fukumori, T. Shimamura, K. Okimura, K. Maeta, T. Miura, F. Sakai, S. Todo
American Journal of Transplantation   13 1976-1988   Aug 2013
A strategy for inhibiting CD40 has been considered as an alternative approach for immunosuppression because of undesirable effects of anti-CD154 monoclonal antibodies (mAbs). Previously, we demonstrated that ASKP1240, which is a fully human anti-C...
Yuki Morooka, Koji Umeshita, Koji Umeshita, Akinobu Taketomi, Akinobu Taketomi, Ken Shirabe, Yoshihiko Maehara, Mayumi Yamamoto, Tsuyoshi Shimamura, Akihiko Oshita, Keiko Kanno, Hideki Ohdan, Naoki Kawagishi, Susumu Satomi, Kaoru Ogawa, Kuniko Hagiwara, Hiroaki Nagano
Surgery Today   43 732-740   Jul 2013
Purpose: To develop a living liver donor (LLD) quality of life (QOL) scale and test its reliability and validity. Methods: We sent a draft questionnaire comprising 38 questions to 965 LLDs from five hospitals. To evaluate test-retest reliability, ...
Kencho Miyashita, Kencho Miyashita, Jong Hon Kang, Akiyoshi Saga, Kazuaki Takahashi, Tsuyoshi Shimamura, Atsushi Yasumoto, Hiraku Fukushima, Susumu Sogabe, Kouhei Konishi, Takumi Uchida, Akira Fujinaga, Takeshi Matsui, Yasuo Sakurai, Kunihiko Tsuji, Hiroyuki Maguchi, Masahiko Taniguchi, Natsumi Abe, Sheikh Mohammad Fazle Akbar, Masahiro Arai, Shunji Mishiro
Hepatology Research   42 870-878   Sep 2012
Aim: In developed countries including Japan, the transmission route of indigenous hepatitis E virus (HEV) infection is obscure. Accordingly, public health implications of indigenous HEV infection have not been well addressed. The aim of this study...
T. Oura, Kenichiro Yamashita, T. Suzuki, D. Fukumori, M. Watanabe, G. Hirokata, K. Wakayama, M. Taniguchi, T. Shimamura, T. Miura, K. Okimura, K. Maeta, H. Haga, K. Kubota, A. Shimizu, F. Sakai, H. Furukawa, Satoru Todo
American Journal of Transplantation   12 1740-1754   Jul 2012
Blockade of the CD40-CD154 costimulatory signal is an attractive strategy for immunosuppression and tolerance induction in organ transplantation. Treatment with anti-CD154 monoclonal antibodies (mAbs) results in potent immunosuppression in nonhuma...
Kenji Wakayama, Moto Fukai, Kenichiro Yamashita, Taichi Kimura, Gentaro Hirokata, Susumu Shibasaki, Daisuke Fukumori, Sanae Haga, Mitsuru Sugawara, Tomomi Suzuki, Masahiko Taniguchi, Tsuyoshi Shimamura, Hiroyuki Furukawa, Michitaka Ozaki, Toshiya Kamiyama, Satoru Todo
Transplant International   25 696-706   Jun 2012
Since prolonged cold preservation of the heart deteriorates the outcome of heart transplantation, a more protective preservation solution is required. We therefore developed a new solution, named Dsol, and examined whether Dsol, in comparison to U...
NAKAHASHI Susumu, TANIGUCHI Masahiko, SHIMAMURA Tsuyoshi, SUZUKI Tomomi, YAMASHITA Kenichiro, OTA Minoru, FURUKAWA Hiroyuki, TODO Satoru
46(6) 573-580   Dec 2011
Akihisa Nagatsu, Masahiko Taniguchi, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Hiroshi Kawakami, Daisuke Abo, Toshiya Kamiyama, Hiroyuki Furukawa, Satoru Todo
World Journal of Gastroenterology   17 3560-3564   Aug 2011
Pancreatic fistula is a quite rare complication in patients who undergo living donor liver transplantation (LDLT). However, in the cases that show pancreatic fistula, the limited volume of the graft and the resultant inadequate liver function may ...
SAWAMURA Atsushi, KUBOTA Nobuhiko, UEGAKI Shinji, HAYAKAWA Mineji, SUZUKI Tomomi, SHIMAMURA Tsuyoshi, GANDO Satoshi
Nihon Kyukyu Igakukai Zasshi   22(7) 337-343   Jul 2011
Yusuke Shimoda, Satoshi Kuroda, Daina Kashiwazaki, Takeshi Asano, Ken Ichiro Yamashita, Masahiko Taniguchi, Tomomi Suzuki, Tsuyoshi Shimamura, Hiroyuki Furukawa, Naoki Nakayama, Kiyohiro Houkin
Neurological Surgery   39 589-594   Jun 2011
In this report, the authors describe a 35-year-old male whose intracranial arteriovenous malformation (AVM) spontaneously disappeared about 2 years after successful living-donor liver transplantation for alcohol-induced liver cirrhosis. Preoperati...
The Japanese journal of nephrology   53(4) 556-583   May 2011
KAMIYAMA Toshiya, HIGE Shuhei, SAKUHARA Yusuke, CHUMA Makoto, SHIMAMURA Tsuyoshi
[Hokkaido igaku zasshi] The Hokkaido journal of medical science   86(3) 127-130   May 2011
In this symposium, we explained etiology, prevention and treatment for hepatocellular carcinoma (HCC). It has been revealed that the carcinogenesis in hepatocellular carcinoma is almost caused by the infection of hepatitis virus B and/or C. Theref...
Toshiya Kamiyama, Kazuaki Nakanishi, Hideki Yokoo, Hirofumi Kamachi, Munenori Tahara, Kenichiro Yamashita, Masahiko Taniguchi, Tsuyoshi Shimamura, Michiaki Matsushita, Satoru Todo
Journal of the American College of Surgeons   211 443-449   Oct 2010
Background: The mortality rates associated with hepatectomy are still not zero. Our aim was to define the risk factors for complications and to evaluate our perioperative management. Study Design: Between 2001 and 2008, 793 consecutive patients (5...
Hiroyuki Furukawa, Tsuyoshi Shimamura, Tomomi Suzuki, Masahiko Taniguchi, Kazuaki Nakanishi, Kenichiro Yamashita, Toshiya Kamiyama, Michiaki Matsushita, Satoru Todo
Journal of Hepato-Biliary-Pancreatic Sciences   17 533-538   Sep 2010
Despite the wide spectrum of selection criteria used by living donor liver transplantation (LDLT) centers in Japan, LDLT for hepatocellular carcinoma (HCC) can achieve an acceptable outcome comparable to the outcome for deceased donor liver transp...
Koichiro Uchida, Masahiko Taniguchi, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Minoru Ota, Toshiya Kamiyama, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Liver Transplantation   16 1062-1068   Sep 2010
Because hepatic vasculatures exhibit variations, a preoperative evaluation of the vascular anatomy and an estimation of the volume of the liver graft are essential for successful adult living donor liver transplantation. Using 3-dimensional (3D) c...
Susumu Shibasaki, Masahiko Taniguchi, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Kenji Wakayama, Gentaro Hirokata, Minoru Ohta, Toshiya Kamiyama, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Clinical Transplantation   24 550-556   Jul 2010
Background: Portal vein (PV) complications in pediatric living donor liver transplantation (LDLT) are often asymptomatic in the early stages after transplantation and can be serious enough to lead to graft failure. There have been few reports on ...
TANIGUCHI Masahiko, FURUKAWA Hiroyuki, SHIMAMURA Tsuyoshi, SUZUKI Tomomi, YAMASHITA Kenichiro, TODO Satoru
Kanzo   51(4) 143-162   Apr 2010
T. Aoyagi, K. Yamashita, T. Suzuki, M. Uno, R. Goto, M. Taniguchi, T. Shimamura, N. Takahashi, T. Miura, K. Okimura, T. Itoh, A. Shimizu, H. Furukawa, S. Todo
American Journal of Transplantation   9 1732-1741   Aug 2009
Blockade of CD40-CD154 signaling pathway is an attractive strategy to induce potent immunosuppression and tolerance in organ transplantation. Due to its strong immunosuppressive effect shown in nonhuman primate experiments, anti-CD154 monoclonal a...
Toshiya Kamiyama, Kazuaki Nakanishi, Hideki Yokoo, Hirofumi Kamachi, Munenori Tahara, Tomomi Suzuki, Tsuyoshi Shimamura, Hiroyuki Furukawa, Michiaki Matsushita, Satoru Todo
Annals of Surgical Oncology   16 1560-1571   Jun 2009
Background: Bridge hepatectomy followed by salvage liver transplantation has been proposed for patients with hepatocellular carcinoma (HCC) and preserved liver function. Methods: Data were prospectively collected for 501 consecutive patients who u...
Shimamura Tsuyoshi, Taniguchi Masahiko, Oota Minoru, Suzuki Tomomi, Yamashita Kenichiro, Furukawa Hiroyuki, Matsushita Michiaki, Todo Satoru
Japanese journal of apheresis   28(2) 125-132   May 2009
Recurrence of hepatitis C is a lingering problem in liver transplantation (LTx) for hepatitis C-associated hepatocellular carcinoma. Since a double filtration plasmapheresis (DFPP) theoretically removes hepatitis C virus (HCV), we applied this mod...
Nobuo Mochizuki, Etsuko Suka, Kunihiro Matsumoto, Osamu Akimoto, Keiko Ohno, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Satoshi Kishino
Biomedical Chromatography   23 267-272   Apr 2009
Therapeutic drug monitoring of sirolimus (rapamycin) is important for immunosuppressive therapy in solid organ transplantation. We have developed a simple and reliable method for determining blood concentrations of sirolimus using reversed-phase H...
Matsushita Michiaki, Shimamura Tsuyoshi, Ota Minoru, Tsuruga Yosuke, Yamashita Kenichiro, Taniguchi Masahiko, Suzuki Tomomi, Kamiyama Toshiya, Furukawa Hiroyuki, Todo Satoru
Japanese journal of apheresis   27(3) 206-210   Oct 2008
Methods of treatment for survival in fulminant hepatitis/LOHF were analyzed from the national survey. Improvement of survival rates of fulminant hepatitis/LOHF needed liver transplantation in addition to artificial liver support. Hemodiafiltration...
NISHIOKA Tsukasa, AKIYAMA Takahiro, TAKAHARA Shiro, TAKAI Kimio, AIKAWA Atsusi, TANAKA Shinichiro, SHIMAMURA Tsuyoshi, YOSHIDA Katunori
43(1) 56-61   Feb 2008
Masahiko Taniguchi, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo
Liver Transplantation   14 263   Feb 2008
T. Oura, M. Taniguchi, T. Shimamura, T. Suzuki, K. Yamashita, M. Uno, R. Goto, M. Watanabe, T. Kamiyama, M. Matsushita, H. Furukawa, S. Todo
American Journal of Transplantation   8 250-252   Jan 2008
In order to obviate a small-for-size graft syndrome (SFSGS), a portacaval (PC) shunt had been considered in a case of adult-to-adult living donor liver transplantation (AA-LDLT). In a recent AA-LDLT case, we adopted the PC shunt to resolve SFSGS; ...
SUZUKI Tomomi, YAMASHITA Kenichiro, TANIGUCHI Masahiko, SHIMAMURA Tsuyoshi, TAKAGI Yuki, YAMAMOTO Mayumi, FURUKAWA Hiroyuki, TODO Satoru
42(6) 622-628   Dec 2007
Tomomi Suzuki, Kenichiro Yamashita, Masahiko Taniguchi, Tsuyoshi Shimamura, Yuki Takagi, Mayumi Yamamoto, Hiroyuki Furukawa, Satoru Todo
Nihon Arukōru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence   42 622-628   Dec 2007
Atsushi Imai, Tomomi Suzuki, Atsushi Sugitani, Tomoo Itoh, Shinya Ueki, Takeshi Aoyagi, Kenichiro Yamashita, Masahiko Taniguchi, Nobuaki Takahashi, Toru Miura, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Satoru Todo
Transplantation   84 1020-1028   Oct 2007
BACKGROUND. CD40-CD154 pathway blockade by anti-CD154 monoclonal antibodies (mAbs) significantly prolongs allograft survival in nonhuman primates. However, thromboembolic complications have prevented clinical application. Thus, blockade of the cou...
Masahiko Taniguchi, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Tetsu Oura, Masaaki Watanabe, Toshiya Kamiyama, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Liver Transplantation   13 932-934   Jun 2007
Shinichiro Magata, Masahiko Taniguchi, Tomomi Suzuki, Tsuyoshi Shimamura, Moto Fukai, Hiroyuki Furukawa, Miri Fujita, Satoru Todo
Journal of Surgical Research   139 7-14   May 2007
Background: Adenosine is known to exert protective roles in hepatic ischemia and reperfusion injury, while all adenosine receptors do not play the cytoprotective roles. We have tested our hypothesis that blockage of adenosine binding to A 1 recept...
Surgery   69(5) 581-586   May 2007
Nobuo Mochizuki, Keiko Ohno, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Satoshi Kishino
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences   847 78-81   Mar 2007
We have developed a simple, rapid and highly sensitive method for determining a plasma or cerebrospinal fluid (CSF) concentrations of individual teicoplanin components using reversed-phase high-performance liquid chromatography followed by electro...
Shinya Ueki, Kenichiro Yamashita, Takeshi Aoyagi, Sanae Haga, Tomomi Suzuki, Tomoo Itoh, Masahiko Taniguchi, Tsuyoshi Shimamura, Hiroyuki Furukawa, Michitaka Ozaki, Kazuo Umezawa, Satoru Todo, Satoru Todo
Transplantation   82 1720-1727   Dec 2006
BACKGROUND. Nuclear factor (NF)-κB plays a crucial role in lymphocyte activation, proliferation, and survival. We examined the immunosuppressive effect of a newly developed NF-κB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ) in allotransplanta...
N. Mochizuki, K. Matsumoto, K. Ohno, T. Shimamura, H. Furukawa, S. Todo, S. Kishino
Transplantation Proceedings   38 3649-3650   Dec 2006
Micafungin, the first candin antifungal drug developed in Japan, has a significant therapeutic effect against deep-seated mycoses caused by Candida or Aspergillus. Little is known, however, about the optimal dosage or disposition of micafungin in ...
KIMURA Shoko, TANIGUCHI Masahiko, YOSHIDA Tadashi, HATTORI Masahiro, SUZUKI Tomomi, SHIMAMURA Tsuyoshi, FURUKAWA Hiroyuki, TODO Satoru
41(5) 459-462   Oct 2006
Toshiya Kamiyama, Toshiya Kamiyama, Masato Takahashi, Takahito Nakagawa, Kazuaki Nakanishi, Hirofumi Kamachi, Tomomi Suzuki, Tsuyoshi Shimamura, Masahiko Taniguchi, Michitaka Ozaki, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Annals of Surgery   244 451-460   Sep 2006
OBJECTIVE: To determine whether detection of hepatocellular carcinoma (HCC) cells by real-time quantitative RT-PCR targeting of alpha-fetoprotein mRNA (AFP mRNA) before or after curative hepatectomy predicts HCC recurrence and patient survival. SU...
Hiroyuki Furukawa, Tsuyoshi Shimamura, Tomomi Suzuki, Masahiko Taniguchi, Kenichiro Yamashita, Toshiya Kamiyama, Michiaki Matsushita, Satoru Todo
Journal of Hepato-Biliary-Pancreatic Surgery   13 393-397   Sep 2006
Transplant surgeons have long dreamed of achieving a complete cure for hepatocellular carcinoma (HCC) by replacing the liver with a new graft. Although the early results of liver transplantation for HCC were disappointing, with 5-year survival les...
Satoshi Kishino, Keiko Ohno, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo
Clinical Transplantation   20 443-449   Jul 2006
No optimal tacrolimus dosage regimen suitable for clinical use in liver transplant recipients has yet been established. The purpose of this study was to determine the factors affecting the optimal dosage and pharmacokinetics of tacrolimus in livin...
Masahiko Taniguchi, Masahiko Taniguchi, Hiroyuki Furukawa, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Minoru Ota, Satoru Todo
Transplantation   81 1747-1749   Jun 2006
Double-filtration plasmapheresis (DFPP) selectively removes high molecular weight substances including hepatitis C virus (HCV). Four live donor liver transplantation (LDLT) recipients with HCV received combination therapy with low-dose interferon ...
Journal of Japan Surgical Society   107(臨時増刊号_2)    Mar 2006
Yoshihide Nagasako, Meang Bong Jin, Hiroshi Miyazaki, Masato Nakayama, Tsuyoshi Shimamura, Hiroyuki Furukawa, Michiaki Matushita, Satoru Todo
Liver Transplantation   12 435-439   Mar 2006
Thrombocytopenia is a frequent finding following living donor hepatectomy. It appears more pronounced in right graft donors than in left graft donors. This study analyzed postoperative thrombocytopenia in 20 living liver donors and examined the ch...
Masahiko Taniguchi, Masahiko Taniguchi, Hiroyuki Furukawa, Tsuyoshi Shimamura, Tomomi Suzuki, Minoru Oota, Yuuya Onodera, Satoru Todo
Transplantation   81 797-799   Mar 2006
In right lobe living donor liver transplantation (RL-LDLT), venous reconstruction of large middle hepatic vein (MHV) tributaries is often necessary. However the standard for reconstruction is unclear. In two recent RL-LDLT cases, we reconstructed ...
Yoshihisa Kodama, Yusuke Sakuhara, Daisuke Abo, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Kazuo Miyasaka
Liver Transplantation   12 465-469   Mar 2006
The purpose of this study was to evaluate the efficacy of percutaneous transluminal angioplasty (PTA) for treatment of hepatic artery stenosis after living donor liver transplantation. Eighteen patients with hepatic artery stenosis after living do...
TANIGUCHI Masahiko, SHIMAMURA Tsuyoshi, SUZUKI Tomomi, FURUKAWA Hiroyuki, TODO Satoru
Kanzo   46(9) 534-542   Sep 2005
In living donor liver transplantation, it could be one of the key points for better prognosis that the recipients with hepatitis C should have prophylactic therapy to prevent hepatitis C recurrence. We performed a retrospective analysis in our 10 ...
Munenori Tahara, Masato Nakayama, Maeng B. Jin, Miri Fujita, Tomomi Suzuki, Masahiko Taniguchi, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Satoru Todo
Transplantation   80 213-221   Jul 2005
Background. Cold ischemia-reperfusion (I/R) injury is a prominent cause of delayed graft function after kidney transplantation. Reactive oxygen species play a crucial role in I/R injury. Edaravone is a synthetic radical scavenger that has been use...
Moto Fukai, Takaaki Hayashi, Ryoichi Yokota, Tsuyoshi Shimamura, Tomomi Suzuki, Masahiko Taniguchi, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Free Radical Biology and Medicine   38 1372-1381   May 2005
Prolonged hepatic warm ischemia has been incriminated in oxidative stress after reperfusion. However, the magnitude of oxidative stress during ischemia has been controversial. The aims of the present study were to elucidate whether lipid peroxidat...
Tomomi Suzuki, Tsuyoshi Shimamura, Masahiko Taniguchi, Kenichiro Yamashita, Hiroyuki Furukawa, Satoru Todo
Nippon rinsho. Japanese journal of clinical medicine   63 1972-1977   Jan 2005
Early attempts of small bowel transplantation (SBTx) were unsuccessful as a result of uncontrolled rejection and infection. Introduction of tacrolimus in the early 1990s improved the outcome, but results were not satisfactory comparing those after...
Satoshi Kishino, Keiko Ohno, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo
Clinical Transplantation   18 676-680   Dec 2004
Micafungin, a new candin antifungal drug, has a good safety profile and a significant therapeutic effect against Candida and Aspergillus. Little is known, however, about the optimal prophylactic dosage and the disposition of micafungin in liver tr...
Kenji Wakayama, Maeng Bong Jin, Maeng Bong Jin, Hiroyuki Furukawa, Satoru Todo, Tsuyoshi Shimamura, Tomomi Suzuki, Masahiro Hattori, Ryouji Yokoyama, Sari Iwasaki, Masanori Sato, Takahito Nakagawa, Noriaki Kurauchi, Hirohumi Kamachi, Toshiya Kamiyama, Michiaki Matsushita
Journal of Hepato-Biliary-Pancreatic Surgery   11 445-448   Dec 2004
The first case of domino liver transplantation from a brain-dead donor in Japan is described. A 49-year-old man with familial amyloidotic polyneuropathy received a cadaver liver, and his nat ive liver was transplanted into a 53-year-old man with p...
Jin Maeng Bong, Shimamura Tsuyoshi, Taniguchi Masahiko, Nagasako Yoshihide, Suzuki Tomomi, Kamiyama Toshiya, Matsushita Michiaki, Furukawa Hiroyuki, Todo Satoru
Journal of Japan Surgical Society   105(10) 674-679   Oct 2004
Tomomi Suzuki, Maeng Bong Jin, Tsuyoshi Shimamura, Kenichiro Yamashita, Masahiko Taniguchi, Masaru Nomura, Ryouichi Yokota, Moto Fukai, Shinichiro Magata, Hiroyuki Horiuchi, Miri Fujita, Kazuro Nagashima, Hiroyuki Furukawa, Satoru Todo
Transplant International   17 574-584   Oct 2004
Three different types of treatment were conducted to clarify the properties of a novel immunomodulator, FTY720, in canine kidney allograft models. Survival, biochemical and hematological tests, pharmacokinetics, and histopathology of grafts and ex...
Gentaro Hirokata, Maeng Bong Jin, Tsuyoshi Shimamura, Tomomi Suzuki, Masahiko Taniguchi, Masahiro Hattori, Minoru Ohta, Hiroyuki Furukawa, Satoru Todo
Acta Hepatologica Japonica   45 308-312   Aug 2004
HIROKATA Gentaro, JIN Maeng Bong, SHIMAMURA Tsuyoshi, SUZUKI Tomomi, TANIGUCHI Masahiko, HATTORI Masahiro, OHTA Minoru, FURUKAWA Hiroyuki, TODO Satoru
Kanzo   45(6) 308-312   Jun 2004
Masahiko Taniguchi, Masahiko Taniguchi, Shinichirou Magata, Tomomi Suzuki, Tsuyoshi Shimamura, Maeng Bong Jin, Junichi Iida, Hiroyuki Furukawa, Satoru Todo
Journal of the American College of Surgeons   198 758-769   May 2004
Background Adenosine, a metabolite of adenosine triphosphate degradation during ischemia, is reported to attenuate ischemia and reperfusion injury in several tissues. Dipyridamole is a nucleoside transport inhibitor that augments endogenous adenos...
Satoshi Kishino, Maki Ogawa, Yoh Takekuma, Mitsuru Sugawara, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Katsumi Miyazaki
Clinical Transplantation   18 124-129   Apr 2004
The urinary ratio of 6β-hydroxycortisol to cortisol (6β-OHF/F) is considered to be the simplest and most practical method for estimation of hepatic cytochrome P450 3A4 (CYP3A4) activity as a non-invasive marker of human in vivo CYP3A4 activity. Ho...
Maeng Bong Jin, Tsuyoshi Shimamura, Masahiko Taniguchi, Yoshihide Nagasako, Tomomi Suzuki, Toshiya Kamiyama, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo
Nippon Geka Gakkai zasshi   105 674-679   Jan 2004
Liver regeneration in living-donor liver transplantation is summarized from the authors' data. In donors, liver function tests recovered to within the normal range 2 weeks after surgery regardless of graft type. At 2 weeks, the volumetric recovery...
Satoshi Kishino, Katsumi Miyazaki, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo
Japanese Pharmacology and Therapeutics   31    Dec 2003
Determination of the changes in tacrolimus pharmacokinetics after liver transplantation and elucidation of the factors influencing the pharmacokinetics of tacrolimus have enable us to manage the target blood level more easily in the early postoper...
Matsushita Michiaki, Shimamura Tsuyoshi, Jin Maeng Bon, Ohta Minoru, Hattori Masahiro, Taniguchi Masahiko, Suzuki Tomomi, Kamiyama Toshiya, Furukawa Hiroyuki, Todo Satoru
Japanese journal of apheresis   22(3) 181-184   Oct 2003
Between September 1997 and July 2003, we have performed 95 cases of living donor liver transplantation (LDLTx), including 17 cases (17.9%) of fulminant hepatic failure. The survival rates of these 17 cases of fulminant hepatic failure at 1, 3 and ...
S. Kishino, Y. Takekuma, M. Sugawara, T. Shimamura, H. Furukawa, S. Todo, Katsumi Miyazaki
Clinical Transplantation   17 412-416   Oct 2003
In adult-to-adult living donor liver transplantation (LDLT), the graft volume is inevitably much smaller than the ideal liver mass (standard liver volume) for the recipient's metabolic demand. Patients with small-for-size grafts are treated with c...
Keisa Takeda, Maeng Bong Jin, Miri Fujita, Moto Fukai, Tsunenori Sakurai, Masato Nakayama, Masahiko Taniguchi, Tomomi Suzuki, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Satoru Todo
Surgery   133 197-206   Feb 2003
Background. A Rho-ROCK signal system induces vascular contraction and neutrophil migration, both of which are characteristic features found with ischemia and reperfusion injury of the liver. We tested our hypothesis that a novel ROCK I inhibitor, ...
Satoshi Kishino, Yoh Takekuma, Mitsuru Sugawara, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Katsumi Miyazaki
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences   780 289-294   Nov 2002
We have developed a simple, rapid and highly sensitive method for determining plasma concentrations of ganciclovir and/or acyclovir by using reversed-phase chromatography followed by pulsed amperometric detection. A linear relationship between the...
FURUKAWA Hiroyuki, SHIMAMURA Tsuyoshi, JIN Maeng Bong, SUZUKI Tomomi, TODO Satoru
28(3) 89-93   Sep 2002
Todo Satoru, Furukawa Hiroyuki, Matsushita Michiaki, Shimamura Tsuyoshi, Jin Men-Bong, Suzuki Tomomi, Taniguchi Masahiko
Journal of Japan Surgical Society   103(5) 408-413   May 2002
Hiroto Ishikawa, Maeng Bong Jin, Toshiro Ogata, Masahiko Taniguchi, Tomomi Suzuki, Tsuyoshi Shimamura, Shinichirou Magata, Hiroyuki Horiuchi, Kenji Ogata, Hiroyuki Masuko, Miri Fujita, Hiroyuki Furukawa, Satoru Todo
Transplantation   73 1041-1048   Apr 2002
Background. In a series of canine liver ischemia experiments, we have shown that amelioration of hepatic injury is achievable by the inhibition of vasoconstriction, cytokine production, platelet aggregation, and neutrophil infiltration. Cyclic ade...
Yasuaki Nakajima, Tsuyoshi Shimamura, Toshiya Kamiyama, Michiaki Matsushita, Naoki Sato, Satoru Todo
Surgery Today   32 48-52   Feb 2002
To determine the safest and most efficient way of performing hepatectomy, the differences in methods employed by Japanese surgeons were examined. In November 1998, a questionnaire on bleeding control during hepatectomy was sent to 270 hospitals lo...
Satoru Todo, Hiroyuki Furukawa, Tsuyoshi Shimamura, Menbon Jin, Tomomi Suzuki
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine   91 Suppl 43-50   Jan 2002
Satoru Todo, Hiroyuki Furukawa, Michiaki Matsushita, Tsuyoshi Shimamura, Men Bong Jin, Tomomi Suzuki, Masahiko Taniguchi
Nippon Geka Gakkai zasshi   103 408-413   Jan 2002
The outcome of liver transplantation for patients with hepatitis B/C virus (HBV/HBC) cirrhosis or with hepatocellular carcinoma(HCC) was deemed pessimistic until the early 1990s due to the high rate of recurrence and mortality. However, with the a...
Maeng Bong Jin, Maeng Bong Jin, Masato Nakayama, Masato Nakayama, Toshiro Ogata, Toshiro Ogata, Miri Fujita, Miri Fujita, Kazuhiro Mino, Kazuhiro Mino, Masahiko Taniguchi, Masahiko Taniguchi, Tomomi Suzuki, Tomomi Suzuki, Tsuyoshi Shimamura, Tsuyoshi Shimamura, Hiroyuki Furukawa, Hiroyuki Furukawa, Satoru Todo, Satoru Todo
Surgery   132 72-79   Jan 2002
Background. Leflunomide and its metabolite, A77 1726, interfere with pyrimidine metabolism and exert potent immunosuppression in experimental organ transplantation. However, clinical use of the agents has been restrained because of an extended hal...
Tsutomu Namieno, Tsutomu Namieno, Tsutomu Namieno, Kazumitsu Koito, Masatoshi Takahashi, Yoshie Une, Kenichiro Yamashita, Tsuyoshi Shimamura
World Journal of Surgery   25 572-577   May 2001
We investigated survival-associated histologic and metastatic spreading modes of intrahepatic, peripheral-type cholangiocarcinomas resected to contribute to surgical control of the tumor. Previous results have been mostly obtained from autopsies, ...
H. Ishikawa, H. Ishikawa, M. B. Jin, M. B. Jin, T. Suzuki, T. Suzuki, T. Shimamura, T. Shimamura, M. Taniguchi, M. Taniguchi, S. Magata, S. Magata, H. Furukawa, H. Furukawa, S. Todo, S. Todo
Transplantation Proceedings   33 982-983   Apr 2001
H. Horiuchi, H. Horiuchi, T. Suzuki, M. Taniguchi, S. Magata, M. B. Jin, H. Ishikawa, K. Ogata, T. Shimamura, H. Furukawa, S. Todo
Transplantation Proceedings   33 848   Apr 2001
G. Takada, G. Takada, M. B. Jin, H. Masuko, K. Yamashita, N. Kitagawa, K. Takeda, N. Sakurai, Y. Kon, H. Horiuchi, T. Shimamura, H. Furukawa, S. Todo
Transplantation Proceedings   33 824-825   Apr 2001
M. Taniguchi, M. Taniguchi, S. Magata, S. Magata, T. Suzuki, T. Suzuki, T. Shimamura, T. Shimamura, M. B. Jin, M. B. Jin, H. Ishikawa, H. Ishikawa, K. Ogata, K. Ogata, H. Furukawa, H. Furukawa, S. Todo, S. Todo
Transplantation Proceedings   33 933   Apr 2001
K. Ogata, K. Ogata, M. B. Jin, T. Suzuki, M. Taniguchi, T. Shimamura, M. Fukai, H. Furukawa, S. Todo
Transplantation Proceedings   33 860-861   Apr 2001
Nakagawa Takahito, Matsushita Michiaki, Kamiyama Toshiya, Kurauchi Nobuaki, Shimamura Tsuyoshi, Sato Naoki, Nakajima Yasuaki, Shimizu Tadashi, Todo Satoru
The Japanese journal of gastroenterological surgery   34(3) 189-196   Mar 2001
Background:Our previous data has shown that preoperative portal vein embolization (PVE) with dehydrated ethanol atrophies the embolized liver lobe and enlarges the presumptive residual liver. We assessed the efficacy of PVE with ethanol in patient...
T. Shimamura, H. Ishikawa, M. Fukai, H. Furukawa, S. Todo
Nihon Naika Gakkai Zasshi   90(1) 21-28   Jan 2001
Tsutomu Namieno, Tsutomu Namieno, Tsutomu Namieno, Kazumitsu Koito, Tsunemi Hiigashi, Masatoshi Takahashi, Tsuyoshi Shimamura, Kenichiro Yamashita, Yukifumi Kondo
Oncology Reports   7 57-61   Dec 2000
Limited surgery for an early gastric carcinoma is advocated, since certain carcinomas have no nodal involvement. However, the endoscopic accuracy of distinguishing each cancer-depth has not been detailed from the standpoint of limited surgery. We ...