論文

査読有り 国際誌
2020年6月8日

Adaptive reduction of male gamete number in the selfing plant Arabidopsis thaliana.

Nature communications
  • Takashi Tsuchimatsu
  • Hiroyuki Kakui
  • Misako Yamazaki
  • Cindy Marona
  • Hiroki Tsutsui
  • Afif Hedhly
  • Dazhe Meng
  • Yutaka Sato
  • Thomas Städler
  • Ueli Grossniklaus
  • Masahiro M Kanaoka
  • Michael Lenhard
  • Magnus Nordborg
  • Kentaro K Shimizu
  • 全て表示

11
1
開始ページ
2885
終了ページ
2885
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41467-020-16679-7

The number of male gametes is critical for reproductive success and varies between and within species. The evolutionary reduction of the number of pollen grains encompassing the male gametes is widespread in selfing plants. Here, we employ genome-wide association study (GWAS) to identify underlying loci and to assess the molecular signatures of selection on pollen number-associated loci in the predominantly selfing plant Arabidopsis thaliana. Regions of strong association with pollen number are enriched for signatures of selection, indicating polygenic selection. We isolate the gene REDUCED POLLEN NUMBER1 (RDP1) at the locus with the strongest association. We validate its effect using a quantitative complementation test with CRISPR/Cas9-generated null mutants in nonstandard wild accessions. In contrast to pleiotropic null mutants, only pollen numbers are significantly affected by natural allelic variants. These data support theoretical predictions that reduced investment in male gametes is advantageous in predominantly selfing species.

リンク情報
DOI
https://doi.org/10.1038/s41467-020-16679-7
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32514036
ID情報
  • DOI : 10.1038/s41467-020-16679-7
  • PubMed ID : 32514036

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