Taichi Sugawara

Profile Information

Affiliation: Faculty of Life Sciences, Kumamoto University

Degree: 博士(学術)(東京大学)

Researcher number: 30758412
J-GLOBAL ID: 201901020720956914
researchmap Member ID: B000360139

Research Interests

Research Areas

Research History

Apr, 2020 - Present

Faculty of Life Sciences, Kumamoto University
Apr, 2015 - Mar, 2020

National Institutes of Natural Sciences
Apr, 2013 - Mar, 2015

日本学術振興会特別研究員 (DC2)

Education

Apr, 2012 - Mar, 2015

Multi-Disciplinary Sciences Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
Apr, 2010 - Mar, 2012

Multi-Disciplinary Sciences Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo

Papers

Expression of Protein Markers in Spermatogenic and Supporting Sertoli Cells Affected by High Abdominal Temperature in Cryptorchidism Model Mice.

Wanta, A, Noguchi, K, Sugawara, T, Sonoda, K, Duangchit, S, Wakayama, T

J. Histochem. Cytochem., 71 387-408, Jul, 2023 Peer-reviewed
Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells.

Furuse M, Nakatsu D, Hempstock W, Sugioka S, Ishizuka N, Furuse K, Sugawara T, Fukazawa Y, Hayashi H

Cell Struct. Funct., 48 1-17, Jan, 2023 Peer-reviewed
Correction to: Quantitative evaluation of spermatogenesis by fluorescent histochemistry (Histochemistry and Cell Biology, (2022), 157, 3, (287-295), 10.1007/s00418-022-02080-6)

Tomohiko Wakayama, Satoshi Yokota, Kazuhiro Noguchi, Taichi Sugawara, Kayoko Sonoda, Arunothai Wanta

Histochemistry and Cell Biology, 157(6) 703, Jun, 2022
Quantitative evaluation of spermatogenesis by fluorescent histochemistry.

Wakayama T, Yokota S, Noguchi K, Sugawara T, Sonoda K, Wanta A.

Histochem. Cell Biol., 157 287-295, Feb, 2022 Peer-reviewed
Angulin-1 seals tricellular contacts independently of tricellulin and claudins.

Sugawara T, Furuse K, Otani T, Wakayama T, Furuse M.

J. Cell Biol., 220 e202005062, Sep, 2021 Peer-reviewedLead author
Angulin-2/ILDR1, a tricellular tight junction protein, does not affect water transport in the mouse large intestine.

Hempstock W, Sugioka S, Ishizuka N, Sugawara T, Furuse M, Hayashi H.

Sci. Rep., 10 10374-10374, Jun, 2020 Peer-reviewed
The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts.

Oda Y*, Sugawara T*, Fukata Y, Izumi Y, Otani T, Higashi T, Fukata M, Furuse M. *: contributed equally

J. Biol. Chem., 295 4289-4302, Mar, 2020 Peer-reviewedLead author
Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity.

Otani T, Nguyen TP, Tokuda S, Sugihara K, Sugawara T, Furuse K, Miura T, Ebnet K, Furuse M.

J. Cell Biol., 218 3372-3396, Oct, 2019 Peer-reviewed
L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.

Nakatsu D, Horiuchi Y, Kano F, Noguchi Y, Sugawara T, Takamoto I, Kubota N, Kadowaki T, Murata M.

Proc. Natl. Acad. Sci. U.S.A., 112 E1067-1076, Mar, 2015 Peer-reviewed
Rab2A is a pivotal switch protein that promotes either secretion or ER-associated degradation of (pro)insulin in insulin-secreting cells.

Sugawara T, Kano F, Murata M.

Sci. Rep., 4 6952, Nov, 2014 Peer-reviewedLead author
JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet

Nakatsu D, Kano F, Taguchi Y, Sugawara T, Nishizono T, Nishikawa K, Oda Y, Furuse M, Murata M.

Genes Cells, 19 565-581, Jul, 2014 Peer-reviewed
PKCδ and ε regulate the morphological integrity of the ER-Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transport via the Golgi apparatus.

Sugawara T, Nakatsu D, Kii H, Maiya N, Adachi A, Yamamoto A, Kano F, Murata M.

Biochim. Biophys. Acta-Mol. Cell Res., 1823 861-875, Apr, 2012 Peer-reviewedLead author

Books and Other Publications

新しい機能を問われだした小胞体-ゴルジ体中間区画

菅原太一, 加納ふみ, 村田昌之

生体の科学細胞の分子構造と機能—核以外の細胞小器官, Oct, 2012

Professional Memberships

Research Projects

A search of novel genes involved in spermatogenesis failure of Down syndrome model mice

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
細胞間結合タイトジャンクションの形態形成メカニズムの解明

科学研究費助成事業, 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2024

古瀬幹夫, 菅原太一
血液精巣関門の構造と真の生理機能

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2024

菅原太一
Reconstitution of paracellular transport by establishment of a claudin-deficient epithelial cell line.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Furuse Mikio, OTANI Tetsuhisa, SUGAWARA Taichi
The molecular mechanism underlying the epithelial barrier formation by tricellular tight junctions

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Furuse Mikio
セミインタクト細胞による、ＥＲＧＩＣでのプロインスリン逆行輸送の定量的可視化解析

科学研究費助成事業, 特別研究員奨励費, 日本学術振興会, Apr, 2013 - Mar, 2015

菅原太一

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Research Interests

Research Areas

Research History

Education

Papers

Books and Other Publications

Professional Memberships

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