論文

査読有り
2013年9月23日

Dearomatizing conjugate addition to quinolinyl amidines for the synthesis of dehaloperophoramidine through tandem arylation and allylation

Angewandte Chemie - International Edition
  • Takayuki Ishida
  • ,
  • Hideo Ikota
  • ,
  • Kei Kurahashi
  • ,
  • Chihiro Tsukano
  • ,
  • Yoshiji Takemoto

52
39
開始ページ
10204
終了ページ
10207
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1002/anie.201305581

Dehaloperophoramidine, the dehalogenated analogue of the marine hexacyclic alkaloid perophoramidine was synthesized. The intramolecular nucleophilic dearomatizing arylation of aminoquinoline initiated by a lithium-iodine exchange and the subsequent direct allylation of the resultant azaenolate afforded a pentacyclic bisamidine compound bearing two contiguous all-carbon quaternary centers in good yield with excellent diastereoselectivity. Copyright © 2013 WILEY-VCH Verlag GmbH &amp
Co. KGaA, Weinheim.

リンク情報
DOI
https://doi.org/10.1002/anie.201305581
J-GLOBAL
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201302268822190860
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23934788
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000329141800006&DestApp=WOS_CPL
ID情報
  • DOI : 10.1002/anie.201305581
  • ISSN : 1433-7851
  • ISSN : 1521-3773
  • J-Global ID : 201302268822190860
  • ORCIDのPut Code : 21836938
  • PubMed ID : 23934788
  • SCOPUS ID : 84884863711
  • Web of Science ID : WOS:000329141800006
  • ORCIDで取得されたその他外部ID : a:1:{i:0;a:1:{s:8:"other-id";s:19:"WOS:000329141800006";}}

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