1993
Acute stroke in cats: Comparison of dynamic susceptibility-contrast MR imaging with T2- and diffusion-weighted MR imaging
Radiology
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- Volume
- 189
- Number
- 1
- First page
- 227
- Last page
- 232
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1148/radiology.189.1.8372198
PURPOSE: To evaluate the hemodynamics of acute stroke in cats by means of dynamic susceptibility-contrast magnetic resonance (MR) imaging compared with standard T2- and diffusion-weighted MR imaging. MATERIALS AND METHODS: Unilateral permanent occlusion of the middle cerebral artery was performed in 18 cats. MR imaging was performed with each method 2 hours (n = 2), 6 hours (n = 10), and 24 hours (n = 11) after occlusion. RESULTS: At every time point, dynamic MR images clearly showed ischemic regions of steady-state signal hyperintensity and areas of less dynamic decrease in signal intensity that corresponded closely to those seen on diffusion-weighted MR images. T2- weighted MR images did not reveal regions of high signal intensity 2 hours after occlusion. The measurements of relative blood volume obtained with the dynamic method were significantly lower in steady-state hyperintense ischemic areas of the affected side than those in the contralateral normal areas at 6 and 24 hours (P <
.001). CONCLUSION: This dynamic method can advance the time of detection of early ischemia in comparison with T2-weighted MR imaging and provides functional information about hemodynamics not provided by other methods of MR imaging.
.001). CONCLUSION: This dynamic method can advance the time of detection of early ischemia in comparison with T2-weighted MR imaging and provides functional information about hemodynamics not provided by other methods of MR imaging.
- Link information
- ID information
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- DOI : 10.1148/radiology.189.1.8372198
- ISSN : 0033-8419
- Pubmed ID : 8372198
- SCOPUS ID : 0027508471