Papers

Jun, 2021

Spatial and temporal variations of flip-angle distributions in the human brain using an eight-channel parallel transmission system at 7T: comparison of three radiofrequency excitation methods.

Radiological physics and technology
  • Tsuyoshi Matsuda
  • ,
  • Ikuko Uwano
  • ,
  • Yuji Iwadate
  • ,
  • Kunihiro Yoshioka
  • ,
  • Makoto Sasaki

Volume
14
Number
2
First page
161
Last page
166
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.1007/s12194-021-00612-8

We investigated the spatial and temporal variations of flip-angle (FA) distributions in the human brain from multiple scans, using an eight-channel parallel transmission (pTx) system at 7T. Nine healthy volunteers were scanned in five sessions using three radiofrequency excitation techniques each time: circular polarization (CP), static pTx, and dynamic pTx. We calculated the coefficients of variation of the FA values within the brain area to evaluate the variations, and the maximum intersession differences in the FA values (Dmax), comparing them between the three methods. The coefficients of variation decreased in the following order: CP, static pTx, and dynamic pTx (median: 20.1%, 13.6%, and 5.7%, respectively; p < 0.001). The average Dmax values were significantly higher for the static pTx (5.4°) than for the dynamic pTx (2.8°) and CP (1.7°) methods (p = 0.004 and 0.001, respectively). Compared to the CP method, the dynamic pTx method at 7T can efficiently minimize spatial variations in the FA distribution with a mild increase in temporal variations. The static pTx method exhibited a remarkably wide temporal variation.

Link information
DOI
https://doi.org/10.1007/s12194-021-00612-8
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33710499
ID information
  • DOI : 10.1007/s12194-021-00612-8
  • Pubmed ID : 33710499

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