論文

査読有り
2021年1月

Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center

Laboratory Animal Research
  • Hiroshi Masuya
  • Daiki Usuda
  • Hatsumi Nakata
  • Naomi Yuhara
  • Keiko Kurihara
  • Yuri Namiki
  • Shigeru Iwase
  • Toyoyuki Takada
  • Nobuhiko Tanaka
  • Kenta Suzuki
  • Yuki Yamagata
  • Norio Kobayashi
  • Atsushi Yoshiki
  • Tatsuya Kushida
  • 全て表示

37
1
開始ページ
6
終了ページ
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.1186/s42826-020-00068-8
出版者・発行元
Springer Science and Business Media LLC

<title>Abstract</title>Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly growing due to the development of genetic modification technology with associated information of genomic sequence and phenotypes. Therefore, data integration technologies to improve the findability, accessibility, interoperability, and reusability of mouse strain data becomes essential for mouse strain repositories. In 2020, the RIKEN BioResource Research Center released an integrated database of bioresources including, experimental mouse strains, <italic>Arabidopsis thaliana</italic> as a laboratory plant, cell lines, microorganisms, and genetic materials using Resource Description Framework-related technologies. The integrated database shows multiple advanced features for the dissemination of bioresource information. The current version of our online catalog of mouse strains which functions as a part of the integrated database of bioresources is available from search bars on the page of the Center (<ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://brc.riken.jp">https://brc.riken.jp</ext-link>) and the Experimental Animal Division (<ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://mus.brc.riken.jp/">https://mus.brc.riken.jp/</ext-link>) websites. The BioResource Research Center also released a genomic variation database of mouse strains established in Japan and Western Europe, MoG+ (<ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://molossinus.brc.riken.jp/mogplus/">https://molossinus.brc.riken.jp/mogplus/</ext-link>), and a database for phenotype-phenotype associations across the mouse phenome using data from the International Mouse Phenotyping Platform. In this review, we describe features of current version of databases related to mouse strain resources in RIKEN BioResource Research Center and discuss future views.

リンク情報
DOI
https://doi.org/10.1186/s42826-020-00068-8
URL
http://link.springer.com/content/pdf/10.1186/s42826-020-00068-8.pdf
URL
http://link.springer.com/article/10.1186/s42826-020-00068-8/fulltext.html
ID情報
  • DOI : 10.1186/s42826-020-00068-8
  • eISSN : 2233-7660

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