2016年6月
Transmission of an H5N8-Subtype Highly Pathogenic Avian Influenza Virus from Infected Hens to Laid Eggs
AVIAN DISEASES
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- 巻
- 60
- 号
- 2
- 開始ページ
- 450
- 終了ページ
- 453
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1637/11312-110315-Reg
- 出版者・発行元
- AMER ASSOC AVIAN PATHOLOGISTS
We showed here that an H5N8-subtype highly pathogenic avian influenza virus (HPAIV) was transmitted to both the internal contents and shells of eggs laid by white leghorn hens experimentally infected with the virus. Seven of eight HPAIV-infected hens laid eggs until 4 days postinoculation (dpi). The mean number of eggs laid per head daily decreased significantly from 0.58 before inoculation to 0.18 after viral inoculation. The virus was detected in the eggs laid by three of the seven hens. Viral transmission was detectable beginning on 3 dpi, and virus titers in tracheal and cloacal swabs from the hens that laid the contaminated eggs exceeded 2.9 log(10) EID50. The level of viral replication and its timing when virus replicates enough to be detected in oviduct after virus inoculation appear to be key factors in the transmission of H5N8 HPAIV from infected hens to laid eggs.
- リンク情報
- ID情報
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- DOI : 10.1637/11312-110315-Reg
- ISSN : 0005-2086
- eISSN : 1938-4351
- PubMed ID : 27309286
- Web of Science ID : WOS:000378086600008