論文

査読有り
2016年12月

Effect of candidate gene polymorphisms on reproductive traits in a Large White pig population

ANIMAL SCIENCE JOURNAL
  • Shuji Sato
  • ,
  • Takashi Kikuchi
  • ,
  • Yoshinobu Uemoto
  • ,
  • Satoshi Mikawa
  • ,
  • Keiichi Suzuki

87
12
開始ページ
1455
終了ページ
1463
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/asj.12580
出版者・発行元
WILEY-BLACKWELL

The objective of this study was to test for association of candidate single nucleotide polymorphisms (SNPs) with sow prolificacy reproductive traits, such as litter size, ovulation rate and lifetime performance, in gilts of a Large White pig population. Preliminary research on 25 animals selected from the high- and low-performance groups of 347 animals with case-control studies indicated that seven genes were associated with total number of piglets born (TNB). Six of the seven genes were associated with reproductive traits, including TNB, number of piglets born alive (NBA) and average weight of piglet weaning (AWW). A MBL2 SNP was significantly associated with TNB and NBA in first parity. A CFB SNP was associated with TNB in first parity. An ACE SNP was associated with TNB in first and second parities. An EGF polymorphism was associated with TNB, NBA and AWW in second parity. A KCNC2 polymorphism was significantly associated with TNB and NBA in second parity. A SLC22A5 SNP was associated with TNB and NBA in second parity. Six candidate SNPs were associated with TNB; the only exception was a PRKAG3 polymorphism. A candidate gene approach enables some of these polymorphisms to be used in genetic improvement programs based on marker-assisted selection.

Web of Science ® 被引用回数 : 3

リンク情報
DOI
https://doi.org/10.1111/asj.12580
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27018129
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000389323700001&DestApp=WOS_CPL