論文

最終著者 責任著者 国際誌
2021年8月15日

Chichibabin/isoChichibabin pyridinium synthesis of ma'edamines C and D.

Bioorganic & medicinal chemistry letters
  • Mika Hirose
  • ,
  • Nao Tanaka
  • ,
  • Toyonobu Usuki

46
開始ページ
128165
終了ページ
128165
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.bmcl.2021.128165
出版者・発行元
Elsevier BV

Ma'edamines C and D were isolated from an Okinawan marine sponge and exhibited a unique tetrasubstituted pyridinium skeleton. The proposed biosynthetic pathway is similar to that of desmosine and isodesmosine, which are elastin-crosslinking amino acids. In this study, first total synthesis of ma'edamines C and D was achieved via Pr(OTf)3-promoted Chichibabin/isoChichibabin pyridinium synthesis starting from the corresponding aldehydes and amine.

リンク情報
DOI
https://doi.org/10.1016/j.bmcl.2021.128165
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34077773
ID情報
  • DOI : 10.1016/j.bmcl.2021.128165
  • ISSN : 0960-894X
  • PubMed ID : 34077773

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