Hashiguchi Takao

J-GLOBAL         Last updated: Jul 17, 2019 at 11:16
 
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Name
Hashiguchi Takao
Affiliation
Kyushu University

Research Areas

 
 

Academic & Professional Experience

 
Apr 2016
 - 
Today
Associate professor, Department of Virology, Faculty of medicine, Kyushu University
 
Apr 2013
 - 
Mar 2016
Assistant professor, Department of Virology, Faculty of medicine, Kyushu University
 
Apr 2012
 - 
Mar 2013
Research associate, Dept of Immunology and Microbiology, The Scripps Research Institute
 
Apr 2010
 - 
Apr 2012
Research associate, Dept of Immunology and Microbiology, The Scripps Research Institute
 

Education

 
Apr 2005
 - 
Mar 2008
Department of Virology, Faculty of medicine, Kyushu University
 
Apr 2003
 - 
Mar 2005
Medical science, Faculty of medicine, Kyushu University
 
Apr 1999
 - 
Mar 2003
Faculty of chemistry, Department of science, Kyushu University
 

Published Papers

 
Tadokoro T, Jahan ML, Ito Y, Tahara M, Chen S, Imai A, Sugimura N, Yoshida K, Saito M, Ose T, Hashiguchi T, Takeda M, Fukuhara H, Maneaka K
The FEBS journal      Jul 2019   [Refereed]
Kubota M, Matsuoka R, Suzuki T, Yonekura K, Yanagi Y, Hashiguchi T* (Corresponding author)
Journal of virology      May 2019   [Refereed]
Mathieu C, Ferren M, Jurgens E, Dumont C, Rybkina K, Harder O, Stelitano D, Madeddu S, Sanna G, Schwartz D, Biswas S, Hardie D, Hashiguchi T, Moscona A, Horvat B, Niewiesk S, Porotto M
Journal of virology      Feb 2019   [Refereed]
Angius F, Smuts H, Rybkina K, Stelitano D, Eley B, Wilmshurst J, Ferren M, Lalande A, Mathieu C, Moscona A, Horvat B, Hashiguchi T, Porotto M, Hardie D
Journal of virology      Nov 2018   [Refereed]
Watanabe S, Shirogane Y, Sato Y, Hashiguchi T, Yanagi Y
Trends in microbiology      Sep 2018   [Refereed]
Sato Y, Watanabe S, Fukuda Y, Hashiguchi T, Yanagi Y, Ohno S
Journal of virology   92(6)    Mar 2018   [Refereed]
Hashiguchi T* (Co-corresponding author), Fukuda Y, Matsuoka R, Kuroda D, Kubota M, Shirogane Y, Watanabe S, Tsumoto K, Kohda D, Plemper RK, Yanagi Y*
Proc Natl Acad Sci U S A.   115(10) 2496-2501   Mar 2018   [Refereed]
Koga R, Kubota M, Hashiguchi T, Yanagi Y, Ohno S
Journal of virology      Feb 2018   [Refereed]
Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE Jr, Meiler J
Structure   25(12) 1820-1828.e2   Dec 2017   [Refereed]
Kubota M, Takeuchi K*, Watanabe S, Ohno S, Matsuoka R, Kohda D, Nakakita SI, Hiramatsu H, Suzuki Y, Nakayama T, Terada T, Shimizu K, Shimizu N, Shiroishi M, Yanagi Y, Hashiguchi T* (Co-corresponding author)
Proc Natl Acad Sci U S A.   113(41) 11579-11584   Oct 2016   [Refereed]
Fusco ML, Hashiguchi T, Cassan R, Biggins JE, Murin CD, Warfield KL, Li S, Holtsberg FW, Shulenin S, Vu H, Olinger GG, Kim DH, Whaley KJ, Zeitlin L, Ward AB, Nykiforuk C, Aman MJ, Berry JD, Saphire EO
PLoS pathog.   11(6) e1005016   Jun 2015   [Refereed]
Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE Jr
Cell   160(5) 893-903   Feb 2015   [Refereed]
Hashiguchi T, Fusco ML, Bornholdt ZA, Lee JE, Flyak AI, Matsuoka R, Kohda D, Yanagi Y, Hammel M, Crowe JE Jr, Saphire EO
Cell   160(5) 904-912   Feb 2015   [Refereed]
Nakashima M*, Shirogane Y*, Hashiguchi T* (Co-first author), Yanagi Y
The Journal of biological chemistry   288(12) 8085-8091   Mar 2013   [Refereed]
Crystallization strategy for the glycoprotein-receptor complex between measles virus hemagglutinin and its cellular receptor SLAM.
Hashiguchi T, Ose T, Kubota M, Maita N, Kamishikiryo J, Maenaka K, Yanagi Y
Protein and peptide letters   19(4) 468-473   Apr 2012   [Refereed]
Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL Jr, Chandran K, Dye JM, Saphire EO
Viruses   4(4) 447-470   Apr 2012   [Refereed]
Olal D, Kuehne AI, Bale S, Halfmann P, Hashiguchi T, Fusco ML, Lee JE, King LB, Kawaoka Y, Dye JM Jr, Saphire EO
Journal of virology   86(5) 2809-2816   Mar 2012   [Refereed]
Hashiguchi T, Ose T, Kubota M, Maita N, Kamishikiryo J, Maenaka K, Yanagi Y
Nat Struct Mol Biol.   18(2) 135-141   Feb 2011   [Refereed]
Hashiguchi T, Maenaka K, Yanagi Y
Frontiers in microbiology   2 247   2011   [Refereed]
Yanagi Y, Takeda M, Ohno S, Hashiguchi T
Current Topics in Microbiology and Immunology   329 13-30   2009   [Refereed]
Tahara M, Takeda M, Shirogane Y, Hashiguchi T, Ohno S, Yanagi Y
Journal of virology   82(9) 4630-4637   May 2008   [Refereed]
Navaratnarajah CK, Vongpunsawad S, Oezguen N, Stehle T, Braun W, Hashiguchi T, Maenaka K, Yanagi Y, Cattaneo R
The Journal of biological chemistry   283(17) 11763-11771   Apr 2008   [Refereed]
Hashiguchi T, Kajikawa M, Maita N, Takeda M, Kuroki K, Sasaki K, Kohda D, Yanagi Y, Maenaka K
Journal of virological methods   149(1) 171-174   Apr 2008   [Refereed]
Hashiguchi T, Kajikawa M, Maita N, Takeda M, Kuroki K, Sasaki K, Kohda D, Yanagi Y, Maenaka K
Proc Natl Acad Sci U S A.   104(49) 19535-19540   Dec 2007   [Refereed]
Takeda M, Tahara M, Hashiguchi T, Sato TA, Jinnouchi F, Ueki S, Ohno S, Yanagi Y
Journal of virology   81(21) 12091-12096   Nov 2007   [Refereed]
Tahara M, Takeda M, Seki F, Hashiguchi T, Yanagi Y
Journal of virology   81(6) 2564-2572   Mar 2007   [Refereed]
Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
Stem cells (Dayton, Ohio)   24(9) 2014-2022   Sep 2006   [Refereed]
Takeda M, Nakatsu Y, Ohno S, Seki F, Tahara M, Hashiguchi T, Yanagi Y
Journal of virology   80(9) 4242-4248   May 2006   [Refereed]

Conference Activities & Talks

 
Structure-guided and computer-aided drug development to ameliorate persistent measles virus infection in the central nervous system [Invited]
Takao Hashiguchi
Japan-UK Workshop on Infectious Disease Research(AMED-英国大使館主催)   21 Jan 2019   
Drug-repositioning screening for anti-viral therapeutics of mumps virus infection
Iori Okabe, Satoshi Shindo, Yuma Sato, Marie Kubota, Aya Ueo, Satoko Otuguro, Katsumi Maenaka, Yusuke Yanagi, Takao Hashiguchi
The 66th Annual meeting of the Japanese Society for Virology   30 Oct 2018   
Measles virus-mediated membrane fusion linked with CNS disorders
Takao Hashiguchi
EMBO Workshop, Membrane fusion in health and disease Cambridge   25 Jun 2018   
モノネガウイルスの細胞侵入およびその阻害機構の研究と創薬への展開 [Invited]
橋口 隆生
AMED 新興再興事業・J-GRID合同シンポジウム 感染症研究連携のフロンティア   23 Mar 2018   
Molecular dissection of virus entry and its inhibition by antibodies/inhibitors [Invited]
Takao Hashiguchi
Immunology at the Forefront - The 9th International Symposium of IFReC   26 Jan 2018   
Molecular basis for Mononegavirus entry and inhibitions by antibodies/inhibitors [Invited]
Takao Hashiguchi
The 16th Awaji International Forum on Infection and Immunity   6 Sep 2017   
Characterization of Neutralizing Antibodies against Measles Virus
Yoshinari Fukuda,Takao Hashiguchi, Shinji Ohno, Yusuke Yanagi
The 64th Annual meeting of the Japanese Society for Virology   24 Oct 2016   
Molecular basis for negative-strand RNA virus entry and neutralization by antibodies [Invited]
Takao Hashiguchi
The 64th Annual meeting of the Japanese Society for Virology   24 Oct 2016   
Tetrameric interaction of the mumps virus hemagglutinin-neuraminidase head domain is critical for triggering membrane fusion
Iori Okabe, Marie Kubota, Shin-ichi Nakakita, Takao Hashiguchi, Yusuke Yanagi
The 64th Annual meeting of the Japanese Society for Virology   23 Oct 2016   
Linear saccharide moiety containing α2,3-linked sialic acid, rather than the sialic acid alone, constitutes a receptor for mumps virus
Marie Kubota, Kaoru Takeuchi, Shumpei Watanabe, Shinji Ohno, Rei Matsuoka, Daisuke Kohda, Shin-ichi Nakakita, Hiroaki Hiramatsu, Yasuo Suzuki, Tetsuo Nakayama, Tohru Terada, Kentaro Shimizu, Nobutaka Shimizu, Yusuke Yanagi, Takao Hashiguchi
The 64th Annual meeting of the Japanese Society for Virology   23 Oct 2016   
Structural basis for Ebola and Marburg virus neutralization by antibodies
Takao Hashiguchi、Yusuke Yanagi、Rei Matsuoka、Daisuke Kohda、Erica Ollmann Saphire
7 Jun 2016   
Inhibitory mechanisms of anti-filovirus antibodies on Marburg and Ebola virus entry [Invited]
Takao Hashiguchi
Institute for Protein Research(IPR) International Seminar IPR / CRED / PDIS Joint Seminar   12 Jan 2016   
Structural basis for filovirus neutralization by antibodies [Invited]
Takao Hashiguchi
The 63rd Annual meeting of the Japanese Society for Virology   25 Nov 2015   
Structures of measles virus hemagglutinin provide virus entry and effective measles vaccine [Invited]
Hashiguchi T., Nakashima, M., Shirogane, Y., Maenaka, K., and Yanagi, Y
The 12th Awaji International Forum on Infection and Immunity   11 Sep 2013   
Structural and functional insight into measles virus hemagglutinin
Hashiguchi T, Kubota M, Nakashima M, Shirogane Y, Ose T, Maenaka K, and Yanagi Y.
7th International Conference on Structural Genomics (ICSG2013-SLS)   30 Jul 2013   
Crystal structure of the measles virus hemagglutinin sheds light on its interaction with cellular receptors and antibodies
Hashiguchi T, Takeda M, Maenaka K, Yanagi Y
The 27th Annual Meeting of American Scociety for Virology   Jul 2008