J-GLOBAL         Last updated: Sep 1, 2019 at 02:42
Hiroshima University
Job title
Doctor of Philisophy (Medicine)(Hiroshima University), MBBS(BRD Medical College, Gorakhpur University, INDIA)
Research funding number

Research Areas


Academic & Professional Experience

May 2005
Mar 2007
Research Assistant, Graduate School of Biomedical Sciences, Hiroshima University
Nov 2003
Apr 2005
Post Doctoral Fellow, Molecular Pathology, International Agency for Research on Cancer, WHO, Lyon
Aug 2003
Oct 2003
Lecturer, Department of Pathology, Nepal Medical College, Kathmandu


Apr 1999
Mar 2003
PhD (Medicine), Graduate School of Medicine, Hiroshima University
Oct 1997
Mar 1999
Foreign Researcher (Neuropathology), Graduate School of Medicine, Hiroshima University
Apr 1995
Sep 1997
Department of Pathology, Faculty of Medicine, Tribhuvan University
Sep 1987
Aug 1992
MBBS, BRD Medical College, Gorakhpur University

Published Papers

Karlowee V, Amatya Vishwa jeet, Takayasu T, Takano M, Yonezawa U, Takeshima Y, Sugiyama K, Kurisu K, Yamasaki F.
Pathobiology   16(1) 1-10   May 2019   [Refereed]
Ueno H, Norose K, Kamimura T, Mihara K, Yamasaki F, Hikosaka K, Amatya Vishwa jeet, Takeshima Y, Kurisu K, Maruyama H.
Intern Med.   58(8) 1157-1162   Apr 2019   [Refereed]
We herein report the case of a 60-year-old man with a "target sign" in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. F-18-fluorodeoxyglucose-positron emission tomograph...
Kai Y, Amatya Vishwa jeet, Kushitani K, Kambara T, Suzuki R, Tsutani Y, Miyata Y, Okada M, Takeshima Y.
Histopathology   74(4) 545-554   Mar 2019   [Refereed]
Amatya Vishwa jeet, Kushitani K, Mawas AS, Miyata Y, Okada M, Kishimoto T, Inai K, Takeshima Y.
Mod Pathol.   32(1) 158   Jan 2019   [Refereed][Invited]
Onishi S, Kajiwara Y, Takayasu T, Kolakshyapati M, Ishifuro M, Amatya Vishwa Jeet, Takeshima Y, Sugiyama K, Kurisu K, Yamasaki F.
World Neurosurg.   119 E890-E897   Nov 2018   [Refereed]
BACKGROUND: Perfusion computed tomography (PCT) reflects blood flow and capillary condition, which is valuable in assessing brain tumors. We evaluated PCT parameters at the tumor (t) and peritumoral (p) region to differentiate malignant brain tumo...
Suzuki R, Amatya Vishwa Jeet, Kushitani K, Kai Y, Kambara T, Takeshima Y.
FRONTIERS IN ONCOLOGY   8(446)    Oct 2018   [Refereed]
Dysregulation of miR-182 and miR-183 has been implicated in the progression of several human cancers. Our previous study showed that miR-182 and miR-183 are upregulated in malignant mesothelioma. However, their biological functions remain unclear....
Matsuda S, Kajihara Y, Abiko M, Mitsuhara T, Takeda M, Karlowee V, Yamaguchi S, Amatya Vishwa Jeet, Kurisu K.
NMC Case Rep J.   5(6) 105-109   Sep 2018   [Refereed]
Hirose T, Nobusawa S, Sugiyama K, Amatya VJ, Fujimoto N, Sasaki A, Mikami Y, Kakita A, Tanaka S, Yokoo H.
Brain Pathol   28(5) 684-694   Sep 2018   [Refereed]
Astroblastoma is a rare, enigmatic tumor of the central nervous system (CNS) which shares some clinicopathologic aspects with other CNS tumors, especially ependymoma. To further clarify the nature of astroblastoma, we performed clinicopathologic a...
Kaichi Y, Tatsugami F, Nakamura Y, Baba Y, Iida M, Higaki T, Kiguchi M, Tsushima S, Yamasaki F, Amatya Vishwa Jeet, Takeshima Y, Kurisu K, Awai K.
Medicine (Baltimore)   97(32) e11670   Aug 2018   [Refereed]
The purpose of this study was to investigate the value of the cerebral blood volume (CBV) obtained with perfusion computed tomography (CT) and the electron density (ED) measured by dual-energy CT for differentiating high- from low-grade glioma (HG...
Amatya Vishwa Jeet, Kushitani K, Kai Y, Suzuki R, Miyata Y, Okada M, Takeshima Y.
Mod Pathol.   31(5) 809-815   May 2018   [Refereed]
Histological morphology alone is not sufficient for the pathological diagnosis of malignant mesothelioma. Positive and negative immunohistochemical markers are necessary to differentiate it from lung adenocarcinoma. As calretinin and D2-40, the re...
Kitagawa H, Kaneko M, Kano M, Ibuki Y, Amatya Vishwa Jeet, Takeshima Y, Hirabayashi N, Hirota S.
Pathol Int.   68(5) 313-317   May 2018   [Refereed]
Collision tumor of the stomach is rare. We report a rare case of a gastric collision tumor consisting of gastrointestinal stromal tumors (GISTs) and leiomyosarcoma (LMS). Computed tomography scan revealed a 15cm sized mass in the posterior wall of...
Yamasaki F, Kinoshita Y, Takayasu T, Usui S, Kolakshyapati M, Takano M, Tsuyuguchi S, Amatya Vishwa Jeet, Akiyama Y, Takeshima Y, Sugiyama K, Kurisu K.
World Neurosurg.   112 E84-E94   Apr 2018   [Refereed]
BACKGROUND: The differentiation of germinoma from other tumors by conventional magnetic resonance imaging (MRI) can be very difficult. The purpose of our study was to determine whether diffusion-weighted imaging (DWI) and single-voxel proton magne...
Prognostic implications of the subcellular localization of survivin in glioblastomas treated with radiotherapy plus concomitant and adjuvant temozolomide.
Saito T, Sugiyama K, Takeshima Y, Amatya Vishwa Jeet, Yamasaki F, Takayasu T, Nosaka R, Muragaki Y, Kawamata T, Kurisu K.
J Neurosurg.   128(3) 679-684   Mar 2018   [Refereed]
Nonenhancing peritumoral hyperintense lesion on diffusion-weighted imaging in glioblastoma: a novel diagnostic and specific prognostic indicator.
Kolakshyapati M, Adhikari RB, Karlowee V, Takayasu T, Nosaka R, Amatya Vishwa Jeet, Takeshima Y, Akiyama Y, Sugiyama K, Kurisu K, Yamasaki F.
J Neurosurg.   128(3) 667-678   Mar 2018   [Refereed]
Kushitani K, Amatya Vishwa Jeet, Mawas AS, Suzuki R, Miyata Y, Okada M, Inai K, Kishimoto T, Takeshima Y.
Oncol Lett.   15(3) 3540-3547   Mar 2018   [Refereed]
Histological distinction between epithelioid mesothelioma (EM) and reactive mesothelial hyperplasia (RMH) can be challenging. The aim of this study was to assess the diagnostic utility of Survivin, Ki-67, and loss of BRCA1-associated protein 1 (BA...
Mawas AS, Amatya Vishwa Jeet, Kushitani K, Kai Y, Miyata Y, Okada M, Takeshima Y.
Sci Rep.   8(1) 134   Jan 2018   [Refereed]
The differential diagnosis of epithelioid mesothelioma from lung adenocarcinoma and squamous cell carcinoma requires the positive and negative immunohistochemical markers of mesothelioma. The IMIG guideline has suggested the use of Calretinin, D2-...
Onishi S, Yamasaki F, Nakano Y, Takayasu T, Amatya Vishwa Jeet, Kolakshyapati M, Takeshima Y, Hirose T, Ichimura K, Sugiyama K, Kurisu K.
Brain Tumor Pathol.   35(1) 41-45   Jan 2018   [Refereed]
Nosaka R, Yamasaki F, Saito T, Takayasu T, Kolakshyapati M, Amatya Vishwa Jeet, Takeshima Y, Sugiyama K, Kurisu K.
J Clin Neurosci.   44(10) 148-154   Oct 2017   [Refereed]
Background: Earlier studies proposed phosphatase and tensin homolog (PTEN) acts as a 3'-specific phosphatidylinositol phosphatase and inhibits the PI3K pathway. Recent reports show that PTEN mRNA expression is significantly downregulated in brain ...
Kuraoka Masatsugu;Amatya Vishwa J;Kushitani Kei;Mawas Amany S;Miyata Yoshihiro;Okada Morihito;Kishimoto Takumi;Inai Kouki;Nishisaka Takashi;Sueda Taijiro;Takeshima Yukio
The American journal of surgical pathology   41(8) 1045-1052   Aug 2017   [Refereed]
:As there are currently no absolute immunohistochemical positive markers for the definite diagnosis of malignant epithelioid mesothelioma, the identification of additional "positive" markers that may facilitate this diagnosis becomes of clinical i...
Karlowee V, Kolakshyapati M, Amatya Vishwa Jeet, Takayasu T, Nosaka R, Sugiyama K, Kurisu K, Yamasaki F.
Childs Nerv Syst.   33(8) 1411-1414   Aug 2017   [Refereed]
Introduction Diffuse leptomeningeal glioneuronal tumor is a new entity under the neuronal and mixed neuronal-glial tumors in the WHO 2016 updated classification and commonly found in children and adolescents. The initial diagnosis is challenging b...
Nakata S, Nobusawa S, Hirose T, Ito S, Inoshita N, Ichi S, Amatya Vishwa Jeet, Takeshima Y, Sugiyama K, Sonoda Y, Haga H, Hirato J, Nakazato Y, Yokoo H.
Am J Surg Pathol.   41(7) 932-940   Jul 2017   [Refereed][Invited]
:Atypical teratoid/rhabdoid tumors (AT/RTs) are rare aggressive tumors of the central nervous system that predominantly affect infants. Although adult AT/RT are rare, accumulated cases have revealed adult-specific AT/RT in the sellar region. Twelv...
Amatya Vishwa Jeet, Kushitani K, Mawas AS, Miyata Y, Okada M, Kishimoto T, Inai K, Takeshima Y.
MODERN PATHOLOGY   30(5) 672-681   May 2017   [Refereed]
Sarcomatoid mesothelioma, a histological subtype of malignant pleural mesothelioma, is a very aggressive tumor with a poor prognosis. Histological diagnosis of sarcomatoid mesothelioma largely depends on the histomorphological feature of spindled ...
Mawas AS, Amatya Vishwa Jeet, Suzuki R, Kushitani K, Mohi El-Din MM, Takeshima Y.
Int J Oncol.   50(3) 1029-1034   Mar 2017   [Refereed]
Malignant mesothelioma is a major asbestos-related cancer with prolonged time lapse from the first exposure of asbestos to the development of mesothelioma. Most of mesothelioma patients show very poor prognosis, thus, an urgent improvement of its ...
Kushitani K, Amatya Vishwa Jeet, Okada Y, Katayama Y, Mawas AS, Miyata Y, Okada M, Inai K, Kishimoto T, Takeshima Y.
Histopathology   70(3) 375-384   Feb 2017   [Refereed]
Karlowee V, Amatya Vishwa Jeet, Hirano H, Takayasu T, Nosaka R, Kolakshyapati M, Yoshihiro M, Takeshima Y, Sugiyama K, Arita K, Kurisu K, Yamasaki F.
Pathobiology   84(2) 99-107   Feb 2017   [Refereed]
Multicentric gliomas are very rare. Due to differences in their tumor types they remain enigmatic. We focused on the pathogenesis of multicentric gliomas and compared their imnnunoprofile with that of solitary gliomas. This retrospective study inc...
Kinoshita Y, Yamasaki F, Usui S, Amatya Vishwa Jeet, Tominaga A, Sugiyama K, Kurisu K.
Childs Nerv Syst.   32(5) 901-904   May 2016   [Refereed]
Amatya Vishwa Jeet, Mawas AS, Kushitani K, Mohi El-Din MM, Takeshima Y.
Int J Oncol.   48(4) 1599-1607   Apr 2016   [Refereed]
Use of Anti-Noxa Antibody for Differential Diagnosis between Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia.
Kushitani K, Amatya Vishwa Jeet, Mawas AS, Miyata Y, Okada M, Takeshima Y.
Pathobiology.   83(1) 33-40   Jan 2016   [Refereed]
Yamasaki F, Takayasu T, Nosaka R, Amatya Vishwa Jeet, Takeshima Y, Yoshihiro M, Kurisu K.
Childs Nerv Syst.   32(1) 189-193   Jan 2016   [Refereed]
Magnetic resonance spectroscopy detection of high lipid levels in intraaxial tumors without central necrosis: a characteristic of malignant lymphoma.
Yamasaki F, Takayasu T, Nosaka R, Amatya VJ, Doskaliyev A, Akiyama Y, Tominaga A, Takeshima Y, Sugiyama K, Kurisu K.
J Neurosurg   122(6) 1370-1379   Jun 2015   [Refereed]
Desmoplastic/nodular medulloblastoma associated with anhidrotic ectodermal dysplasia.
Watanabe Y, Yamasaki F, Nakamura K, Kajiwara Y, Takayasu T, Hirose T, Amatya Vishwa Jeet, Sugiyama K, Kobayashi M, Kurisu K.
International Cancer Conference Journal   2(3) 178-182   Jul 2013   [Refereed]
CD9 expression as a favorable prognostic marker for patients with malignant mesothelioma.
Amatya VJ, Takeshima Y, Aoe K, Fujimoto N, Okamoto T, Yamada T, Kishimoto T, Morimoto C, Inai K.
Oncol Rep   29(1) 21-28   Jan 2013   [Refereed]
Aoe K, Amatya VJ, Fujimoto N, Ohnuma K, Hosono O, Hiraki A, Fujii M, Yamada T, Dang NH, Takeshima Y, Inai K, Kishimoto T, Morimoto C
Clinical Cancer Research   18(5) 1447-1456   Mar 2012   [Refereed]
Lymphomas and glioblastomas: differences in the apparent diffusion coefficient evaluated with high b-value diffusion-weighted magnetic resonance imaging at 3T.
Doskaliyev A, Yamasaki F, Ohtaki M, Kajiwara Y, Takeshima Y, Watanabe Y, Takayasu T, Amatya Vishwa Jeet, Akiyama Y, Sugiyama K, Kurisu K.
Eur J Radiol.   81(2) 339-344   Feb 2012   [Refereed]
Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas.
Mahmoud OM, Tominaga A, Amatya Vishwa Jeet, Ohtaki M, Sugiyama K, Sakoguchi T, Kinoshita Y, Takeshima Y, Abe N, Akiyama Y, El-Ghoriany AI, Abd Alla AK, El-Sharkawy MA, Arita K, Kurisu K, Yamasaki F.
Eur J Radiol.   80(2) 412-417   Nov 2011   [Refereed]
Amatya Vishwa Jeet, Takeshima Y, Kushitani K, Yamada T, Morimoto C, Inai K.
Oncology Reports   26(6) 1369-1375   Sep 2011   [Refereed]
Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma.
Kohno H, Amatya Vishwa Jeet, Takeshima Y, Kushitani K, Hattori N, Kohno N, Inai K.
Oncol Rep.   24(2) 423-431   Aug 2010   [Refereed]
Jin Longnan;Amatya Vishwa Jeet;Takeshima Yukio;Shrestha Looniva;Kushitani Kei;Inai Kouki
Hiroshima Journal of Medical Sciences   59(2) 27-33   Jun 2010
Tsukiji Hiromi;Takeshima Yukio;Amatya Vishwa J;Kushitani Kei;Inai Kouki
Histopathology   56(7)    2010
Ohara Shinya;Oue Naohide;Matsubara Akio;Mita Koji;Hasegawa Yasuhisa;Hayashi Tetsutaro;Usui Tsuguru;Amatya Vishwa Jeet;Takeshima Yukio;Kuniyasu Hiroki;Yasui Wataru
Cancer science   99(8)    2008
:Regenerating islet-derived family, member 4 (REG4, which encodes Reg IV) is a candidate marker for cancer and inflammatory bowel disease. We investigated the potential prognostic role of Reg IV immunostaining in clinically localized prostate canc...
Amatya Vishwa Jeet;Naumann Ulrike;Weller Michael;Ohgaki Hiroko
Acta neuropathologica   110(2)    2005
:Methylation of the promoter region of tumor suppressor genes may be associated with transcriptional silencing and tumor progression. The 5' region of the TP53 gene does not contain a CpG island, but a basal promoter region of 85 bp is essential f...
Amatya V J;Kamiya M;Kurihara H;Gouda T;Horiguchi K;Hirato J;Nakazato Y
Clinical neuropathology   20(2)    Feb 2001   [Refereed]
:We describe a case of dysplastic glioneuronal lesion in the right cerebellar hemisphere. A 13-year-old boy presented with headache since 1998. He had no neurological deficits. The computerized tomograph (CT) scan showed prominent calcification, a...
Amatya V J;Takeshima Y;Sugiyama K;Yokozaki H;Inai K
Pathology international   49(12)    1999
:A 2-year-old girl presented with a single episode of generalized seizure. Magnetic resonance imaging examination showed an intracranial mass with a diameter of 2.5 cm in the right parieto-occipital region of the cerebrum. These clinicoradiologica...

Conference Activities & Talks

CM2-3: Exploration of the novel immunohistochemical markers of epithelioid mesothelioma and lung adenocarcinoma [Invited]
Vishwa Jeet Amatya
The 64th Autumn Annual Meeting of The Japanese Society of Pathology   23 Nov 2018   
p35: miR-182 and miR-183 promote cell proliferation and invasion by targeting FOXO1 in mesothelioma
Rui Suzuki
The 64th Autumn Annual Meeting of The Japanese Society of Pathology   22 Nov 2018   
Shumpei Onishi
The 18th International Symposium on Pediatric Neuro-Oncology   30 Jun 2018   Society for Neuro-Oncology
3-I-16: Glypican-1 is the positive marker to differentiate epithelioid mesothelioma from lung adenocarcinoma
Amatya Vishwa Jeet
The 107th Annual Meeting of the Japanese Society of Pathology   23 Jun 2018   
1-D-15 Utility of Annexin-8 Immunostaining for Differential Diagnosis of Mesothelioma and Lung Cancer
Kushitani K
The 107th Annual Meeting of the Japanese Society of Pathology   21 Jun 2018