Hidemichi Watari

Profile Information

Affiliation: Hokkaido University

Degree: 博士（医学）(北海道大学)

J-GLOBAL ID: 201401064784256134
researchmap Member ID: B000240828

External link: http://kaken.nii.ac.jp/d/r/10344508.ja.html

Research Areas

Life sciences / Obstetrics and gynecology /

Research History

2010 - 2013

Hokkaido University

Papers

Molecular-targeted therapies and precision medicine for endometrial cancer.

Takashi Mitamura, Peixin Dong, Kei Ihira, Masataka Kudo, Hidemichi Watari

Japanese journal of clinical oncology, 49(2) 108-120, Feb 1, 2019 Peer-reviewed
Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer.

Dong P, Xiong Y, Yu J, Chen L, Tao T, Yi S, Hanley SJB, Yue J, Watari H, Sakuragi N

Oncogene, 37(39) 5257-5268, Sep, 2018 Peer-reviewed
miR-203 inhibits ovarian tumor metastasis by targeting BIRC5 and attenuating the TGFβ pathway.

Wang B, Li X, Zhao G, Yan H, Dong P, Watari H, Sims M, Li W, Pfeffer LM, Guo Y …

Journal of experimental & clinical cancer research : CR, 37(1) 235, Sep, 2018 Peer-reviewed
miR-363 confers taxane resistance in ovarian cancer by targeting the Hippo pathway member, LATS2.

Zeinab Mohamed, Mohamed Kamel Hassan, Safwat Okasha, Takashi Mitamura, Sarah Keshk, Yusuke Konno, Tatsuya Kato, Sherif F El-Khamisy, Yusuke Ohba, Hidemichi Watari

Oncotarget, 9(53) 30053-30065, Jul 10, 2018 Peer-reviewed
Comparison of human papillomavirus genotyping and cytology triage, COMPACT Study: Design, methods and baseline results in 14 642 women.

Satomi Aoyama-Kikawa, Hiromasa Fujita, Sharon J B Hanley, Mitsunori Kasamo, Kokichi Kikuchi, Toshihiko Torigoe, Yoshihiro Matsuno, Akiko Tamakoshi, Takayuki Sasaki, Motoki Matsuura …

Cancer science, 109(6) 2003-2012, Jun, 2018 Peer-reviewed
miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation.

Peixin Dong, Ying Xiong, Junming Yue, Sharon J B Hanley, Hidemichi Watari

Oncotarget, 9(33) 23253-23263, May 1, 2018 Peer-reviewed
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells

Tao Zhang, Guannan Zhao, Chuanhe Yang, Peixin Dong, Hidemichi Watari, Lin Zeng, Lawrence M. Pfeffer, Junming Yue

Oncology Letters, 15(4) 4432-4438, Apr 1, 2018 Peer-reviewed
B7H3 As a Promoter of Metastasis and Promising Therapeutic Target.

Peixin Dong, Ying Xiong, Junming Yue, Sharon J B Hanley, Hidemichi Watari

Frontiers in oncology, 8 264-264, 2018 Peer-reviewed
Tumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion.

Peixin Dong, Ying Xiong, Junming Yue, Sharon J B Hanley, Hidemichi Watari

Frontiers in oncology, 8 386-386, 2018 Peer-reviewed
Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors.

Peixin Dong, Ying Xiong, Junming Yue, Sharon J B Hanley, Noriko Kobayashi, Yukiharu Todo, Hidemichi Watari

Frontiers in genetics, 9 471-471, 2018 Peer-reviewed
The Anti-tumor Effect of Cabozantinib on Ovarian Clear Cell Carcinoma In Vitro and In Vivo

Makiko Nakatani, Hidemichi Watari, Takashi Mitamura, Lei Wang, Yutaka Hatanaka, Kanako C. Hatanaka, Kohei Honda, Toshiyuki Nomura, Hiroshi Nishihara, Shinya Tanaka …

ANTICANCER RESEARCH, 37(11) 6125-6132, Nov, 2017 Peer-reviewed
Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells

Guannan Zhao, Qinghui Wang, Qingqing Gu, Wenan Qiang, Jian-Jun Wei, Peixin Dong, Hidemichi Watari, Wei Li, Junming Yue

ONCOTARGET, 8(55) 94666-94680, Nov, 2017 Peer-reviewed
Phase III trial to confirm the superiority of pelvic and para-aortic lymphadenectomy to pelvic lymphadenectomy alone for endometrial cancer: Japan Clinical Oncology Group Study 1412 (SEPAL-P3)

Hidemichi Watari, Hiroshi Katayama, Taro Shibata, Kimio Ushijima, Toyomi Satoh, Takashi Onda, Daisuke Aoki, Haruhiko Fukuda, Nobuo Yaegashi, Noriaki Sakuragi

JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 47(10) 986-990, Oct, 2017 Peer-reviewed
Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.

Dong P, Xiong Y, Hanley SJB, Yue J, Watari H

Journal of experimental & clinical cancer research : CR, 36(1) 150, Oct, 2017 Peer-reviewed
Additive effect of rikkunshito, an herbal medicine, on chemotherapy-induced nausea, vomiting, and anorexia in uterine cervical or corpus cancer patients treated with cisplatin and paclitaxel: results of a randomized phase II study (JORTC KMP-02)

Shunsuke Ohnishi, Hidemichi Watari, Maki Kanno, Yoko Ohba, Satoshi Takeuchi, Tempei Miyaji, Shunsuke Oyamada, Eiji Nomura, Hidenori Kato, Toru Sugiyama …

JOURNAL OF GYNECOLOGIC ONCOLOGY, 28(5) e44, Sep, 2017 Peer-reviewed
Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma

Hiroaki Itamochi, Tetsuro Oishi, Nao Oumi, Satoshi Takeuchi, Kosuke Yoshihara, Mikio Mikami, Nobuo Yaegashi, Yasuhisa Terao, Kazuhiro Takehara, Kimio Ushijima …

BRITISH JOURNAL OF CANCER, 117(5) 717-724, Aug, 2017 Peer-reviewed
iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling.

Xiong Y, Sun F, Dong P, Watari H, Yue J, Yu MF, Lan CY, Wang Y, Ma ZB

Journal of experimental & clinical cancer research : CR, 36(1) 48, Apr, 2017 Peer-reviewed
KLF4 expression enhances the efficacy of chemotherapy drugs in ovarian cancer cells

Baojin Wang, Airong Shen, Xuan Ouyang, Guannan Zhao, Ziyun Du, Wenying Huo, Tao Zhang, Yinan Wang, Chuanhe Yang, Peixin Dong …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 484(3) 486-492, Mar, 2017 Peer-reviewed
EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis

Kei Ihira, Peixin Dong, Ying Xiong, Hidemichi Watari, Yosuke Konno, Sharon J. B. Hanley, Masayuki Noguchi, Noriyuki Hirata, Futoshi Suizu, Takahiro Yamada …

ONCOTARGET, 8(8) 13509-13520, Feb, 2017 Peer-reviewed
Lentiviral CRISPR/Cas9 vector mediated miR-21 gene editing inhibits the epithelial to mesenchymal transition in ovarian cancer cells

Wenying Huo, Guannan Zhao, Jinggang Yin, Xuan Ouyang, Yinan Wang, Chuanhe Yang, Baojing Wang, Peixin Dong, Zhixiang Wang, Hidemichi Watari …

JOURNAL OF CANCER, 8(1) 57-64, 2017 Peer-reviewed

Misc.

419

「それぞれの生」支持療法の工夫嘔気対策・栄養管理シスプラチン/パクリタキセル療法による嘔気・嘔吐・食欲不振に対する六君子湯の効果

大西俊介, 渡利英道, 勘野真紀, 大場洋子, 竹内聡, 宮路天平, 小山田隼佑, 野村英司, 加藤秀則, 杉山徹 …

日本癌治療学会学術集会抄録集, 55回 WS5-5, Oct, 2017
BRCA陽性白金製剤感受性再発卵巣癌に対するolaparibの第III相試験 SOLO2

田村研治, 松本光史, 中井英勝, 榎本隆之, 竹原和宏, 齋藤俊章, 渡利英道, 渡辺麻子, 藤原恵一

日本癌治療学会学術集会抄録集, 55回 O10-1, Oct, 2017
卵巣明細胞癌患者由来異種移植片モデルの樹立と特性解析

朝野拓史, 遠藤大介, 國友美穂子, 本田弘平, 野村俊之, 渡利英道

日本癌治療学会学術集会抄録集, 55回 O11-2, Oct, 2017
胃癌の子宮頸部転移が疑われた1例

前田悟郎, 武田真人, 奥聡, 朝野拓史, 小林由佳子, 石塚泰也, 丸川活司, 今井一章, 遠藤大介, 岡田宏美 …

日本臨床細胞学会雑誌, 56(Suppl.2) 689-689, Oct, 2017
子宮体部粘液性腺癌の2例

小林由佳子, 武田真人, 奥聡, 朝野拓史, 前田悟郎, 石塚泰也, 丸川活司, 岡田宏美, 三田村卓, 保坂昌芳 …

日本臨床細胞学会雑誌, 56(Suppl.2) 718-718, Oct, 2017
子宮頸部絨毛腺管状腺癌の1例

奥聡, 武田真人, 朝野拓史, 今井一章, 小林由佳子, 前田悟郎, 石塚泰也, 丸川活司, 岡田宏美, 三田村卓 …

日本臨床細胞学会雑誌, 56(Suppl.2) 813-813, Oct, 2017
再発卵巣癌の治療長期生存を目指して

渡利英道

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 42-42, Sep, 2017
卵巣明細胞癌患者由来異種移植片モデルの樹立と特性解析

朝野拓史, 遠藤大介, 加藤達矢, 金野陽輔, 三田村卓, 國友美穂子, 本田弘平, 野村俊之, 渡利英道, 櫻木範明

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 56-56, Sep, 2017
Parasitic dissecting leiomyoma(DL)の1例

石塚泰也, 工藤正尊, 藤井タケル, 能代究, 三田村卓, 金野陽輔, 加藤達矢, 渡利英道

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 100-100, Sep, 2017
ベセスダシステムとWHO新分類(2014)の整合性を考えた今後の子宮頸がん検診

藤田博正, 保坂昌芳, 工藤正隆, 渡利英道, 櫻木範明

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 103-103, Sep, 2017
閉経後の外陰症例の治療経過の検討

小林由佳子, 武田真人, 前田悟郎, 山口正博, 福本俊, 小林範子, 藤野敬史, 渡利英道, 工藤正尊, 櫻木範明

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 128-128, Sep, 2017
悪性腹膜中皮腫の1例

奥聡, 武田真人, 朝野拓史, 小林由佳子, 井平圭, 野崎綾子, 金野陽輔, 加藤達矢, 工藤正尊, 渡利英道 …

北日本産科婦人科学会総会・学術講演会プログラム・抄録集, 65回 134-134, Sep, 2017
MRIによる子宮体癌と子宮癌肉腫の鑑別に関する検討

常田慧徳, 加藤扶美, 朝野拓史, 野崎綾子, 井平圭, 三田村卓, 金野陽輔, 加藤達矢, 渡利英道, 飯嶋由紀 …

日本医学放射線学会秋季臨床大会抄録集, 53回 S470-S471, Aug, 2017
婦人科癌術後下肢リンパ浮腫患者に対する治療介入がQOLに及ぼす影響

小林範子, 藤野敬史, 武田真人, 渡利英道, 青山誠, 櫻木範明

女性心身医学, 22(1) 69-69, Jun, 2017
当科におけるロボット支援腹腔鏡下子宮悪性腫瘍手術の初期導入成績について

加藤達矢, 工藤正尊, 朝野拓史, 嶋田知紗, 野崎綾子, 井平圭, 金野陽輔, 保坂昌芳, 渡利英道, 櫻木範明

産婦人科手術, (28) 156-156, Jun, 2017
子宮体癌2018年版・子宮頸癌2017年版 (第2章)【初回治療】に関して

小林裕明, 近藤英司, 進伸幸, 寺井義人, 戸板孝文, 新倉仁, 渡利英道, 河野善明

日本婦人科腫瘍学会雑誌, 35(3) 434-434, Jun, 2017
子宮頸部円錐切除術前後におけるHPVタイピング検査の有用性の検討

金野陽輔, 朝野拓史, 嶋田知紗, 井平圭, 加藤達矢, 小林範子, 武田真人, 渡利英道, 工藤正尊, 櫻木範明

日本婦人科腫瘍学会雑誌, 35(3) 525-525, Jun, 2017
卵巣明細胞癌患者由来異種移植片モデルの樹立と特性解析

朝野拓史, 渡利英道, 遠藤大介, 國友美穂子, 本田弘平, 野村俊之, 畑中豊, 畑中佳奈子

日本婦人科腫瘍学会雑誌, 35(3) 529-529, Jun, 2017
BRCA変異陽性PSR卵巣癌患者を対象としたolaparibの単独維持療法の第III相試験 SOLO-2

松本光史, 温泉川真由, 中井英勝, 榎本隆之, 竹原和宏, 齋藤俊章, 渡利英道, 渡辺麻子, 藤原恵一

日本婦人科腫瘍学会雑誌, 35(3) 532-532, Jun, 2017
腹水貯留原発不明癌の診断確定に腹水セルブロックが有用であった一例

井平圭, 朝野拓史, 嶋田知紗, 野崎綾子, 遠藤大介, 金野陽輔, 加藤達矢, 武田真人, 渡利英道, 櫻木範明

日本婦人科腫瘍学会雑誌, 35(3) 615-615, Jun, 2017

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