Jun Ueda

J-GLOBAL         Last updated: Nov 6, 2019 at 14:01
 
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Name
Jun Ueda
E-mail
junuedaasahikawa-med.ac.jp
URL
http://hyouka04.asahikawa-med.ac.jp/html/100000662_en.html
Affiliation
Asahikawa Medical University
Section
Center for Advanced Research and Education
Job title
Associate Professor
Degree
Ph.D.(Kyoto University)

Profile

Research Interests and Keywords: Epigenetics, Hypoxia, Stem Cells (Embryonic Stem Cells), Germ Cells, Transcription Factors, Cancer, Live-cell Imaging, Knockin Mouse, Gene Editing

Interested in epigenetic dynamics during mammalian development and in oncogenesis (tumorigenesis).

Research Areas

 
 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Associate Professor, Center for Advanced Research and Education, Asahikawa Medical University
 
Apr 2017
 - 
Today
Visiting Associate Professor, College of Life and Health Sciences, Chubu University
 
Oct 2014
 - 
Mar 2017
Assistant Professor, Center for Education in Laboratory Animal Research, Chubu University
 
Jan 2011
 - 
Oct 2014
Assistant Professor, Research Institute for Microbial Diseases, Osaka University
 
May 2009
 - 
Dec 2010
Research Fellow A, Lorenz Poellinger Group, Cancer Science Institute of Singapore, National University of Singapore
 
Jul 2006
 - 
May 2009
Research Scientist, Mammalian Germ Cell Biology (Dr. Mitinori Saitou), RIKEN CDB
 

Published Papers

 
Classification of Cell Nuclei Using CNN Features
Iwahori Y, Tsukada Y, Iwamoto T, Funahashi K, Ueda J, Bhuyan MK
International Conference on Intelligence Science   849 195-208   Sep 2019   [Refereed]
Kitaura F, Yuno M, Fujita T, Wakana S, Ueda J, Yamagata K, Fujii H
PLOS ONE   14(7) e0220199   Jul 2019   [Refereed]
Omori Y, Ono Y, Tanino M, Karasaki H, Yamaguchi H, Furukawa T, Enomoto K, Ueda J, Sumi A, Katayama J, Muraki M, Taniue K, Takahashi K, Ambo Y, Shinohara T, Nishihara H, Sasajima J, Maguchi H, Mizukami Y, Okumura T, Tanaka S
Gastroenterology   156(3) 647-661   Feb 2019   [Refereed]
Contour-Aware Residual W-Net for Nuclei Segmentation.
Das S, Deka A, Iwahori Y, Bhuyan MK, Iwamoto T, Ueda J
Procedia Computer Science   159 1479-1488   Sep 2019   [Refereed]
Heterochromatin-mediated inhibition of cardiac proliferation
Oyama K, Ueda J, Kamiya H
Precision Medicine   1(2) 215-220   Nov 2018   [Invited]
Molecular basis of intraductal papillary mucinous neoplasm of the pancreas
Kawabata H, Mizukami Y, Okada T, Sato H, Hayashi A, Goto T, Ueda J, Ono Y, Karasaki H, Okumura T
KAN・TAN・SUI (Japan)   77(5) 1003-1009   Nov 2018   [Invited]
Takahashi T, Okeyo KO, Ueda J, Yamagata K, Washizu M, and Oana H
Scientific Reports   8(1) 13684   Sep 2018   [Refereed]
Histone variants and cancer: The linkage between cancer microenvironment and epigenome
Ueda J, Mizukami Y, Ohkuri T
The Cell   50(5) 52-56   May 2018   [Invited]
Nishikawa K, Itoi F, Nagahara M, Jose M, Matsunaga A, Ueda J, Iwamoto T
Journal of Assisted Reproduction and Genetics   35(2) 251-256   Feb 2018   [Refereed]
Ho JC, Abdullah LN, Pang QY, Jha S, Chow EK, Yang H, Kato H, Poellinger L, Ueda J, Lee KL
PLOS ONE   12(11) e0188051   Nov 2017   [Refereed]
Extraction of Cell Nuclei using CNN Features
Tsukada Y, Iwahori Y, Funahashi K, Jose M, Ueda J, Iwamoto T
Procedia Computer Science   112 1633-1640   Sep 2017   [Refereed]
Histone variants and cancer
Ueda J, Ohkuri T
The Cell   49(8) 30-34   Jul 2017
Semba Y, Harada A, Maehara K, Oki S, Meno C, Ueda J, Yamagata K, Suzuki A, Onimaru M, Nogami J, Okada S, Akashi K, Ohkawa Y
Nucleic Acids Research      May 2017   [Refereed]
Yamaguchi L, Nishiyama A, Misaki T, Johmura Y, Ueda J, Arita K, Nagao K, Obuse C, Nakanishi M
Scientific Reports   7(1) 55   Mar 2017   [Refereed]
Ueda J, Harada A, Urahama T, Machida S, Maehara K, Hada M, Makino Y, Nogami J, Horikoshi N, Osakabe A, Taguchi H, Tanaka H, Tachiwana H, Yao T, Yamada M, Iwamoto T, Isotani A, Ikawa M, Tachibana T, Okada Y, Kimura H, Ohkawa Y, Kurumizaka H, Yamagata K
Cell Reports   18(3) 593-600   Jan 2017   [Refereed]
Sato Y, Kujirai T, Arai R, Asakawa H, Ohtsuki C, Horikoshi N, Yamagata K, Ueda J, Nagase T, Haraguchi T, Hiraoka Y, Kimura A, Kurumizaka H, Kimura H.
Journal of Molecular Biology   428(20) 3885-3902   Oct 2016   [Refereed]
Epigenetic dynamics: Cellular memories that respond dynamically to environmental changes and stimuli.
Jun Ueda
Annual Report of Research Institute of Life and Health Sciences   12 73-76   Mar 2016
Correspondence to Pasteurella pneumotropica infection: Application of oxidized water for clean-up operation.
Miki Nagahara, Ayumi Matsunaga, Yoshiaki Fujita, Mami Jose, Miyuki Ishisaka, Jun Ueda and Takashi Iwamoto
Annual Report of Research Institute of Life and Health Sciences   12 92-95   Mar 2016
Jolene Caifeng Ho, Jun Ueda, and Takeshi Shimizu
Histology & Histopathology   31 41-50   Jan 2016   [Refereed][Invited]
Tatsuma Yao, Jun Ueda, Tetsuya Kobayashi, Mayuko Hori, and Kazuo Yamagata
Journal of Mammalian Ova Research   32(4) 149-157   Oct 2015   [Refereed][Invited]
Generation of MethylRO mouse to study DNA methylation dynamics of normal and pathological states
Jun Ueda, Kazuo Yamagata
Journal of Clinical and Experimental Medicine   253(6) 523-524   May 2015   [Invited]
DNA methylation dynamics studies using DNA methylation reporter mouse, MethylRO
Ueda, J., Maehara, K., Ohkawa, Y. and Yamagata, K.
Experimental Medicine (Jikkenigaku, Japanese Review)   33(3) 481-489   Feb 2015   [Invited]
Ueda J, Ho JC, Lee KL, Kitajima S, Yang H, Sun W, Fukuhara N, Zaiden N, Chan SL, Tachibana M, Shinkai Y, Kato H, Poellinger L
Molecular and Cellular Biology   34(19) 3702-3720   Sep 2014   [Refereed]
Ueda J, Maehara K, Mashiko D, Ichinose T, Yao T, Hori M, Sato Y, Kimura H, Ohkawa Y, Yamagata K
Stem Cell Reports   2 910-924   Jun 2014   [Refereed]
Sato Y, Mukai M, Ueda J, Muraki M, Stasevich TJ, Horikoshi N, Kujirai T, Kita H, Kimura T, Hira S, Okada Y, Hayashi-Takanaka Y, Obuse C, Kurumizaka H, Kawahara A, Yamagata K, Nozaki N, Kimura H
Scientific Reports   3 2436   Aug 2013   [Refereed]
Hypoxia and Epigenetics
Jun Ueda and Imari Mimura
The CELL   45(9) 13-16   Jul 2013   [Invited]
Hasuwa H, Ueda J, Ikawa M, Okabe M
Science   341(6141) 71-73   Jul 2013   [Refereed]
Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, Knowles BB, Solter D, Fu XY
Genes & Development   27 1378-1390   Jun 2013   [Refereed]
Yamagata K, Ueda J
Development, Growth & Differentiation   55(4) 378-389   May 2013   [Refereed][Invited]
Yamaji M, Ueda J, Hayashi K, Ohta H, Yabuta Y, Kurimoto K, Nakato R, Yamada Y, Shirahige K, Saitou M
Cell Stem Cell   12 368-382   Mar 2013   [Refereed]
Shimizu T, Ueda J, Ho JC, Iwasaki K, Poellinger L, Harada I, Sawada Y
Stem Cells   30(7) 1394-1404   Jul 2012   [Refereed]
Yamagata K, Ueda J, Mizutani E, Saitou M, Wakayama T
Developmental Biology   346(1) 90-101   Oct 2010   [Refereed]
Epsztejn-Litman S, Feldman N, Abu-Remaileh M, Shufaro Y, Gerson A, Ueda J, Deplus R, Fuks F, Shinkai Y, Cedar H, Bergman Y
Nature Structural & Molecular Biology   15(11) 1176-1183   Nov 2008   [Refereed]
Nishida M, Kato M, Kato Y, Sasai N, Ueda J, Tachibana M, Shinkai Y, Yamaguchi M
Genes to Cells   12(7) 877-888   Jul 2007   [Refereed]
Histone Lysine Methylation and Epigenetics.
Ueda J, Shinkai Y
Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme   51 2096-2101   Nov 2006   [Refereed]
The Function of Wiz Protein in G9a/GLP Histone Methyltransferase Complexes
Jun Ueda
Kyoto University      Sep 2006   [Refereed]
Ueda J, Tachibana M, Ikura T, Shinkai Y
Journal of Biological Chemistry   281(29) 20120-20128   Jul 2006   [Refereed]
Tachibana M, Ueda J, Fukuda M, Takeda N, Ohta T, Iwanari H, Sakihama T, Kodama T, Hamakubo T, Shinkai Y
Genes & Development   19(7) 815-826   Apr 2005   [Refereed]
Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y
Genes & Development   16(14) 1779-1791   Jul 2002   [Refereed]

Misc

 
Immunostaining of cultured cells using anti-H3K9me2 antibody
Jun Ueda
Cell Signaling Technology      2009   [Invited]

Books etc

 
ニュー・サイエンス社   Jul 2013   
培風館   May 2010   ISBN:4563078077
米田 悦啓
共立出版   May 2007   ISBN:4320056558

Conference Activities & Talks

 
Extraction of Cell Nuclei using CNN Features
Tsukada Y, Iwahori Y, Funahashi K, Jose M, Ueda J, Iwamoto T
21st International Conference on Knowledge-Based and Intelligent Information & Engineering Systems   Sep 2017   
Testis-Specific Histone Variant H3t Gene is Essential for Entry into Spermatogenesis. [Invited]
Jun Ueda
Society for the Study of Reproduction 2017 Annual Meeting   16 Jul 2017   
Epigenetic and Chromatin Dynamics Studies during Differentiation and Developmental Processes, using Genetically Modified Mice. [Invited]
Jun Ueda
Nagoya City University, Department of Medicine   19 Jul 2016   
Mouse Testis Specific Histone H3 Variant, H3mmT Is Essential for Spermatogenesis and Ensures the Entry into Meiosis
Jun Ueda
International Symposium on Chromatin Structure, Dynamics, and Function   25 Aug 2015   
Epigenetic dynamics studies in tumorigenesis and development [Invited]
Jun Ueda
The 3rd Cancer and Metabolism Research Meeting   17 Jul 2015   
DNA methylation dynamics studies using DNA methylation reporter mouse, MethylRO
Jun Ueda
Chubu University, College of Bioscience and Biotechnology, 24th O-say Open Seminar   18 May 2015   
Epigenetic dynamics studies in tumorigenesis and development [Invited]
Jun Ueda
The 14th Congress of the Japanese Society for Regenerative Medicine   21 Mar 2015   
The discovery of mouse testis specific histone H3 variant H3mmT and its role in spermatogenesis [Invited]
Jun Ueda
The 2nd Histone Variant Research Meeting   28 Feb 2015   
The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth. [Invited]
Ueda J, Ho JC, Lee KL, Kitajima S, Yang H, Sun W, Fukuhara N, Zaiden N, Chan SL, Tachibana M, Shinkai Y, Kato H, Poellinger L.
The 37th Annual Meeting of the Molecular Biology Society of Japan   26 Oct 2014   
Heterochromatin dynamics during differentiation process revealed by the DNA methylation reporter mouse, MethylRO [Invited]
Jun Ueda
The 1st Epigenetics Research Meeting of Nagoya City University   5 Sep 2014   
Jun Ueda
BIKEN Summer School   22 Aug 2014   
Heterochromatin dynamics during differentiation process revealed by the DNA methylation reporter mouse, MethylRO.
Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y., and Yamagata, K.
IIAS Research Conference 2014 ‘Chromatin Decoding’   12 May 2014   
Heterochromatin dynamics during differentiation process revealed by DNA methylation reporter mouse, MethylRO
Jun Ueda, Kazumitsu Maehara, Daisuke Mashiko, Takako Ichinose, Tatsuma Yao, Mayuko Hori, Yasuyuki Ohkawa and Kazuo Yamagata
Keystone Symposia, Chromatin Mechanisms and Cell Physiology   23 Mar 2014   Thomas Jenuwein and Shelley L. Berger
Hypoxia mediates tumourigenesis epigenetically via the H3K9 methylation regulators G9a and Jmjd1a
Jolene Caifeng Ho, Jun Ueda, Kian Leong Lee, Shojiro Kitajima, Henry Yang, Wendi Sun, Noriko Fukuhara, Norazean Zaiden, Shing Leng Chan, Makoto Tachibana, Yoichi Shinkai , Hiroyuki Kato and Lorenz Poellinger
Keystone Symposia "Sensing and Signaling of Hypoxia: Interfaces with Biology and Medicine"   8 Jan 2014   
Imaging global epigenetic dynamics during mouse pre-implantation development [Invited]
Jun Ueda and Kazuo Yamagata
2. The 85th Annual Meeting of the Genetics Society of Japan   21 Sep 2013   
Epigenetic dynamics studies in tumorigenesis and development [Invited]
Jun Ueda
1st Hypoxia Research Meeting, Tokyo   6 Jul 2013   
Role of the Hypoxia-Inducible Histone H3K9 Demethylase Jmjd1a and the H3K9 Methyltransferase G9a in Stem Cell Self-Renewal and Tumorigenesis.
Jun Ueda, Kian Leong Lee, Jolene Caifeng Ho, Henry Yang, Noriko Fukuhara, Shing Leng Chan, Makoto Tachibana, Yoichi Shinkai, Hiroyuki Kato, and Lorenz Poellinger
Keystone Symposia “Advances in Hypoxic Signaling”   Feb 2012   
Survival and death of epiblast cells in ES derivation process revealed by long-term live-cell imaging of Oct4 reporter system.
Ueda J, Yamagata K, Mizutani E, Saitou M, and Wakayama T
Stem Cell Society Singapore Symposium   2009   
Wiz, a novel transcriptional co-repressor, links G9a/GLP histone methyltransferases to CtBP co-repressors.
Ueda J, Tachibana M, and Shinkai Y
Keystone Symposia “Epigentics and Chromatin Remodeling in Development”   Jan 2006   

Teaching Experience

 
 

Research Grants & Projects

 
The Ministry of Education,Culture,Sports,Science and Technology (MEXT): Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2019 - Mar 2022    Investigator(s): Jun Ueda
The Akiyama Life Science Foundation: Grant
Project Year: Apr 2018 - Mar 2019    Investigator(s): Jun Ueda
Kato Memorial Bioscience Foundation: Medical Science Field
Project Year: Apr 2017 - Mar 2019    Investigator(s): Jun Ueda
The Ministry of Education, Culture, Sports, Science and Technology - Japan: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2016 - Mar 2019    Investigator(s): Jun Ueda
The Ministry of Education, Culture, Sports, Science and Technology - Japan: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Project Year: Apr 2016 - Mar 2018    Investigator(s): Jun Ueda
Takeda Science Foundation: 2016年度ライフサイエンス研究奨励
Project Year: Apr 2016 - Mar 2017    Investigator(s): Jun Ueda
Chubu University Grant B
Chubu University: 
Project Year: Apr 2015 - Mar 2017    Investigator(s): Jun Ueda
Keystone Symposium: Epigentics and Chromatin Remodeling in Development: Keystone Scholarship
Project Year: 2006 - 2006    Investigator(s): Jun Ueda

Education

 
Apr 2001
 - 
Jun 2006
Yoichi Shinkai's Lab, Graduate School of Biostudies, Kyoto University
 
Apr 1997
 - 
Mar 2001
Masatoshi Maki's Lab, School of Agricultural Sciences, Nagoya University
 

Committee Memberships

 
2018
 - 
Today
The Journal of Biochemistry  Advisory Board
 
Apr 2015
 - 
Mar 2018
The National Institute of Science and Technology Policy (NISTEP)  Special Researcher