周新宇 (Xinyu Zhou) - マイポータル

基本情報

Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy.

Chunhuan Jin, Xinyu Zhou, Minhui Xu, Hiroki Okanishi, Ryuichi Ohgaki, Yoshikatsu Kanai

Scientific reports 15(1) 2903-2903 2025年1月23日
Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.

Xinyu Zhou, Ryuichi Ohgaki, Chunhuan Jin, Minhui Xu, Hiroki Okanishi, Hitoshi Endou, Yoshikatsu Kanai

Journal of pharmacological sciences 154(3) 182-191 2024年3月
Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2.

Takafumi Kato, Tsukasa Kusakizako, Chunhuan Jin, Xinyu Zhou, Ryuichi Ohgaki, LiLi Quan, Minhui Xu, Suguru Okuda, Kan Kobayashi, Keitaro Yamashita …

Nature communications 13(1) 4714-4714 2022年8月11日

Elucidation of LAT1 Inhibition-Driven Tumor Cell Senescence and SASP-Mediated Immune Recruitment.

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up 2025年7月 - 2027年3月