Yoshiki Sawa

Profile Information

J-GLOBAL ID: 201501017473619560
researchmap Member ID: B000247648

External link: https://kaken.nii.ac.jp/d/r/00243220.ja.html

Research Interests

Research Areas

Research History

Apr, 2021 - Present

特任教授, 大阪大学大学院医学系研究科
Oct, 1989 - Jan, 1992

フンボルト財団留学生, ドイツMax Planck研究所

Papers

1216

JCS/JSCVS/JCC/CVIT 2023 Guideline Focused Update on Indication and Operation of PCPS/ECMO/IMPELLA.

Takashi Nishimura, Yasutaka Hirata, Takayuki Ise, Hiroyuki Iwano, Hironori Izutani, Koichiro Kinugawa, Takeshi Kitai, Takayuki Ohno, Tomohito Ohtani, Takahiro Okumura …

Circulation journal : official journal of the Japanese Circulation Society, Apr 5, 2024
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia

Kenichiro Shimatani, Hiromu Sato, Kazuhiko Mizukami, Atsuhiro Saito, Masao Sasai, Jun-Ichiro Enmi, Kenichi Watanabe, Masazumi Kamohara, Yoshichika Yoshioka, Shigeru Miyagawa …

Journal of Cardiovascular Translational Research, Feb 20, 2024
Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment

Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba …

iScience, 27(2) 108992-108992, Feb, 2024
The Efficacy of Second-Stage Endovascular Repair Strategy for Acute Type A Aortic Dissection.

Fumio Yamana, Toru Kuratani, Keitaro Domae, Tomohiko Sakamoto, Masatoshi Hata, Yukitoshi Shirakawa, Takafumi Masai, Yoshiki Sawa

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 15266028231214206-15266028231214206, Dec 5, 2023
Effect of morphological change on the maturation of human induced pluripotent stem cell-derived cardiac tissue in rotating flow culture

Akihiro Hashida, Taro Nakazato, Toshimasa Uemura, Li Liu, Shigeru Miyagawa, Yoshiki Sawa, Masahiro Kino-oka

Regenerative Therapy, Dec, 2023 Peer-reviewed
Thoracic and cardiovascular surgeries in Japan during 2020 : Annual report by the Japanese Association for Thoracic Surgery.

Goro Matsumiya, Yukio Sato, Hiroya Takeuchi, Tomonobu Abe, Shunsuke Endo, Yasutaka Hirata, Michiko Ishida, Hisashi Iwata, Takashi Kamei, Nobuyoshi Kawaharada …

General thoracic and cardiovascular surgery, Nov 28, 2023
Mid-term outcomes of surgical aortic valve replacement using a mosaic porcine bioprosthesis with concomitant mitral valve repair.

Haruhiko Sugimori, Tatsuya Nakao, Yukikatsu Okada, Yutaka Okita, Hitoshi Yaku, Junjiro Kobayashi, Hideyuki Uesugi, Shuichiro Takanashi, Toshiaki Ito, Tadaaki Koyama …

Heart and vessels, Oct 16, 2023
Pleiotropic effects of extracellular vesicles from induced pluripotent stem cell-derived cardiomyocytes on ischemic cardiomyopathy: A pre-clinical study.

Yuji Tominaga, Takuji Kawamura, Emiko Ito, Maki Takeda, Akima Harada, Kosuke Torigata PhD, Ryoto Sakaniwa, Yoshiki Sawa, Shigeru Miyagawa

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Aug 21, 2023
Developing Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction

Junjun Li, Xiang Qu, Li Liu, Lingjun Li, Ying Hua, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Nagako Sougawa …

Advanced Fiber Materials, Jul 31, 2023
Thoracic and cardiovascular surgeries in Japan during 2019 : Annual report by the Japanese Association for Thoracic Surgery.

Kenji Minatoya, Yukio Sato, Yasushi Toh, Tomonobu Abe, Shunsuke Endo, Yasutaka Hirata, Michiko Ishida, Hisashi Iwata, Takashi Kamei, Nobuyoshi Kawaharada …

General thoracic and cardiovascular surgery, 71(10) 595-628, Jul 20, 2023
Preoperative higher right ventricular stroke work index increases the risk of de novo aortic insufficiency after continuous-flow left ventricular assist device implantation.

Shusaku Maeda, Koichi Toda, Kazuo Shimamura, Kei Nakamoto, Masataka Igeta, Yasushi Sakata, Yoshiki Sawa, Shigeru Miyagawa

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, Jul 19, 2023
3D puzzle-inspired construction of large and complex organ structures for tissue engineering

Zheng-Tian Xie, Jinfeng Zeng, Shigeru Miyagawa, Yoshiki Sawa, Michiya Matsusaki

Materials Today Bio, 100726-100726, Jul, 2023
Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction model.

Emiko Ito, Ai Kawamura, Takuji Kawamura, Maki Takeda, Akima Harada, Noriko Mochizuki-Oda, Yoshiki Sawa, Shigeru Miyagawa

Scientific reports, 13(1) 10530-10530, Jun 29, 2023
Postoperative cerebral infarction and arrhythmia after pulmonary lobectomy in Japan: a retrospective analysis of 77,060 cases in a national clinical database.

Daisuke Kimura, Hiroyuki Yamamoto, Shunsuke Endo, Eriko Fukuchi, Hiroaki Miyata, Ikuo Fukuda, Hitoshi Ogino, Yoshiki Sawa, Masayuki Chida, Masahito Minakawa

Surgery today, May 5, 2023
3D printing of collagen scaffold with enhanced resolution in a citrate-modulated Gellan gum microgel bath.

Zheng-Tian Xie, Jinfeng Zeng, Dong-Hee Kang, Shigeyoshi Saito, Shigeru Miyagawa, Yoshiki Sawa, Michiya Matsusaki

Advanced healthcare materials, e2301090, May 5, 2023
Short-Term Outcomes of Impella Support in Japanese Patients With Cardiogenic Shock Due to Acute Myocardial Infarction - Japanese Registry for Percutaneous Ventricular Assist Device (J-PVAD).

Yuki Ikeda, Junya Ako, Koichi Toda, Atsushi Hirayama, Koichiro Kinugawa, Yoshio Kobayashi, Minoru Ono, Takashi Nishimura, Naoki Sato, Takahiro Shindo …

Circulation journal : official journal of the Japanese Circulation Society, 87(5) 588-597, Apr 25, 2023
ONO-1301 enhances post-transplantation survival of human induced pluripotent stem cell-derived cardiac tissue sheet by promoting angiogenesis.

Xiang Qu, Junjun Li, Li Liu, Jingbo Zhang, Ying Hua, Kota Suzuki, Akima Harada, Masako Ishida, Noriko Yoshida, Daisuke Okuzaki …

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 42(6) 716-729, Feb 10, 2023
Enhanced myocardial blood flow in ischemic cardiomyopathy by a slow-release synthetic prostacyclin agonist combined with coronary artery bypass grafting: The first human study in a Phase I/IIa clinical trial.

Takuji Kawamura, Daisuke Yoshioka, Masashi Kawamura, Ryohei Matsuura, Ai Kawamura, Yusuke Misumi, Tsubasa Mikami, Yoshiki Sawa, Shigeru Miyagawa

Frontiers in cardiovascular medicine, 10 1047666-1047666, 2023
Safety confirmation of induced pluripotent stem cell-derived cardiomyocyte patch transplantation for ischemic cardiomyopathy: first three case reports.

Takuji Kawamura, Yoshito Ito, Emiko Ito, Maki Takeda, Tsubasa Mikami, Takura Taguchi, Noriko Mochizuki-Oda, Masao Sasai, Tomomi Shimamoto, Yukako Nitta …

Frontiers in cardiovascular medicine, 10 1182209-1182209, 2023
Mitochondrial Transfer Induced by Adipose-Derived Mesenchymal Stem Cell Transplantation Improves Cardiac Function in Rat Models of Ischemic Cardiomyopathy.

Daisuke Mori, Shigeru Miyagawa, Takuji Kawamura, Daisuke Yoshioka, Hiroki Hata, Takayoshi Ueno, Koichi Toda, Toru Kuratani, Miwa Oota, Kotoe Kawai …

Cell transplantation, 32 9636897221148457-9636897221148457, 2023

Misc.

1590

補助人工心臓—循環管理のすべて : 研修医からの質問443 ; 急性心不全 ; 治療 : 非薬物療法

澤芳樹, 吉岡大輔, 川村匡

救急・集中治療, 34(1) 215-219, 2022
胸部ステントグラフト内挿術における脳脊髄液ドレナージの有用性と合併症について

松本遼太, 島村和男, 倉谷徹, 四條崇之, 前田孝一, 山下築, 井手亨, 横田純己, 上野高義, 戸田宏一 …

日本胸部外科学会定期学術集会, 74回 COP29-4, Oct, 2021
血管再生医療の現状と課題急性炎症と慢性炎症に着目した動物実験の重要性下肢虚血の虚血炎症環境下における投与細胞生着率改善の工夫

三宅啓介, 宮川繁, 原田明希摩, 澁谷卓, 澤芳樹

脈管学, 61(Suppl.) S136-S136, Oct, 2021
心移植後早期の心臓同種移植血管症におけるインターロイキン-31と内膜線維性肥厚の関連性(Association of Interleukin-31 with Intimal Fibrous Proliferation in Cardiac Allograft Vasculopathy in the Early Phase after Heart Transplantation)

白記達也, 市堀泰裕, 大谷朋仁, 溝手勇, 木岡秀隆, 塚本泰正, 中村大輔, 横井研介, 井手盛子, 中本敬 …

日本心臓病学会学術集会抄録, 69回 YIA2-4, Sep, 2021
心移植後早期の心臓同種移植血管症におけるインターロイキン-31と内膜線維性肥厚の関連性(Association of Interleukin-31 with Intimal Fibrous Proliferation in Cardiac Allograft Vasculopathy in the Early Phase after Heart Transplantation)

白記達也, 市堀泰裕, 大谷朋仁, 溝手勇, 木岡秀隆, 塚本泰正, 中村大輔, 横井研介, 井手盛子, 中本敬 …

日本心臓病学会学術集会抄録, 69回 YIA-6, Sep, 2021
脳死右片肺移植後生じた肺動脈狭窄に対し、外科的に肺動脈形成術を施行した1例

永田秀樹, 柴田明有美, 河中聡之, 木村賢二, 福井絵里子, 狩野孝, 大瀬尚子, 舟木壮一郎, 南正人, 平将生 …

移植, 56(1) 77-77, Jul, 2021
心臓臓器移植におけるAMR治療の実態とrituximab(遺伝子組換え)使用に関する全国使用実態調査の結果

縄田寛, 吉岡大輔, 小野稔, 秋山正年, 澤芳樹, 齋木佳克, 中川健, 江川裕人

移植, 56(1) 43-52, Jul, 2021
血液透析患者における経カテーテル的大動脈弁置換術後の弁構造劣化予測因子の検討

増山慧, 水井理之, 前田孝一, 島村和男, 倉谷徹, 坂口悠介, 坂田泰史, 澤芳樹, 猪阪善隆

日本透析医学会雑誌, 54(Suppl.1) 514-514, May, 2021
SHD治療における心エコー図の役割:実況!SHD治療ガイド経カテーテル的大動脈弁植込み術における心エコー図の重要性

竹田泰治, 仙石薫子, 溝手勇, 島村和男, 倉谷徹, 澤芳樹, 坂田泰史

超音波医学, 48(Suppl.) S233-S233, Apr, 2021
BAG Cochaperone 5の欠失は若年性拡張型心筋症の原因となる(Loss of BAG Cochaperone 5 Causes Juvenile-onset Dilated Cardiomyopathy)

Hakui Hideyuki, Asano Yoshihiro, Kioka Hidetaka, Miyashita Yohei, Kuramoto Yuki, Takahashi Yusuke, Yamamoto Hironori, Nishimura Shunsuke, Ohtani Tomohito, Sawa Yoshiki …

日本循環器学会学術集会抄録集, 85回 YIA-4, Mar, 2021
Fib4-indexによる左室補助人工心臓装着患者の予後予測(Fib4-index can be a Prognostic Factor in Patients with Left Ventricular Assist Device)

小島聡子, 中本敬, 大谷朋仁, 世良英子, 赤澤康裕, 飯田祐一郎, 戸田宏一, 彦惣俊吾, 澤芳樹, 坂田泰史

日本循環器学会学術集会抄録集, 85回 OJ59-7, Mar, 2021
Fib4-index can be a Prognostic Factor in Patients with Left Ventricular Assist Device(和訳中)

小島聡子, 中本敬, 大谷朋仁, 世良英子, 赤澤康裕, 飯田祐一郎, 戸田宏一, 彦惣俊吾, 澤芳樹, 坂田泰史

日本循環器学会学術集会抄録集, 85回 OJ59-7, Mar, 2021
NCD(National Clinical Database)の10年を振り返る-課題と展望- Japan TVT registryの現状、課題、展望

前田孝一, 伊苅裕二, 林田健太郎, 小林順二郎, 斎藤滋, 志水秀行, 富田英, 澤芳樹

日本外科学会雑誌, 122(2) 269-271, Mar, 2021
Global Vascular Guidelineを踏まえた治療戦略透析CLTI患者に対するバイパスにおけるGlobal Limb Anatomic Staging Systemの重要性

三宅啓介, 中村隆, 藤村博信, 倉谷徹, 戸田宏一, 澁谷卓, 澤芳樹

日本心臓血管外科学会学術総会抄録集, 51回 SY5-4, Feb, 2021
上行・弓部を含む広範胸部大動脈疾患に対する治療戦略

政田健太, 倉谷徹, 島村和男, 金啓和, 井手亨, 松本遼太, 上野高義, 戸田宏一, 澤芳樹

日本心臓血管外科学会学術総会抄録集, 51回 PR4-3, Feb, 2021
ハイブリッド手術室における術者眼部への重篤な放射線被曝とその防護に関する検討

横田純己, 松本遼太, 山田裕, 井手亨, 政田健太, 金啓和, 島村和男, 倉谷徹, 澤芳樹

日本心臓血管外科学会学術総会抄録集, 51回 OP41-4, Feb, 2021
HMGB1はPDGFRα陽性骨髄間葉系細胞を障害心筋へ誘導し、心筋梗塞後adverse remodeling進行を抑制する

後藤隆純, 宮川繁, 玉井克人, 木戸高志, 松浦良平, 澤芳樹

再生医療, 20(1) 70-77, Feb, 2021
心臓移植後8週目および12ヵ月目における光干渉断層撮影および血管内超音波検査によるプラーク進行の評価(Plaque Progression Assessed by Serial Optical Coherence Tomography and Intravascular Ultrasound Findings at 8-week and 12-month after Heart Transplantation)

白記達也, 溝手勇, 塚本泰正, 木岡秀隆, 中村大輔, 横井研介, 井手盛子, 竹田泰治, 彦惣俊吾, 澤芳樹 …

日本心血管インターベンション治療学会抄録集, 29回 1322-1322, Feb, 2021
Plaque Progression Assessed by Serial Optical Coherence Tomography and Intravascular Ultrasound Findings at 8-week and 12-month after Heart Transplantation(和訳中)

白記達也, 溝手勇, 塚本泰正, 木岡秀隆, 中村大輔, 横井研介, 井手盛子, 竹田泰治, 彦惣俊吾, 澤芳樹 …

日本心血管インターベンション治療学会抄録集, 29回 1322-1322, Feb, 2021
マウス下肢虚血モデルにおける筋芽細胞集塊投与の血管および骨格筋新生効果

三宅啓介, 宮川繁, 原田明希摩, 澤芳樹

日本再生医療学会総会(Web), 20th, 2021

Research Projects

心筋再生療法のメカニズム究明のための心筋ミトコンドリア機能のイメージング

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

森大輔, 澤芳樹, 永井健治, 寒川延子, 松田知己, 宮川繁
Creating "3D mini heart" for transplantation of heart failure

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
Safety and Effectiveness of Stentless Mitral Valve for Mitral Stenosis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2021

Yaku Hitoshi
Development of heart failure treatment by new device using extracellular matrix modulating cardiac stem cell niche

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

Sawa Yoshiki, SEKIGUCHI Kiyotoshi
Study of drug discovery using cardiomyocytes derived from iPS cells in cardiovascular diseases

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Sawa Yoshiki
Development of the treatment of cardiac failure using a nanosphere (NS) preparation encapsulated with a therapeutic agent for myocardial regeneration

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

SAWA Yoshiki, FUKUSHIMA Satsuki, SOGAWA Nagako, IMANISHI Yukiko
Creation of Functional Materials Using Polymer Self Assembly and Biomedical Application

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016

AKASHI Mitsuru, KIDA Toshiyuki, MATSUSAKI Michiya, AKAGI Takami, SHIMA Fumiaki, AJIRO Hiroharu, TABATA Masashi, MURAOKA Masahiro, WAKU Tomonori, HIRANO Hiroshi, SAWA Yoshiki, HASHIMOTO Koji
The development of surgical treatment targeting myocardial stiffness in damaged myocardium

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

SAWA Yoshiki, NISHI Hiroyuki, YOSHIKAWA Yasushi, MIYAGAWA Shigeru, FUKUSHIMA Sarsuki
Developing microRNA research in cardiac failure

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2014

SAWA Yoshiki, MIYAGAWA Shigeru, YOSHIKAWA Yasushi, FUKUSHIMA Satsuki, NISHI Hiroyuki
Developement of a new stentless mitral valve for clinical application

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014

YAKU Hitoshi, SAWA Yoshiki, UMEZU Mitsuo, NAKATANI Satoshi, HASHIMOTO Kazuhiro, KASEGAWA Hitoshi
Across-the-board study for treatment strategy of type B aortic dissection

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014

KURATANI Toru, SAWA Yoshiki, SHIRAKAWA Yukitoshi, YOSHIKAWA Yasushi, TORIKAI Kei, SHIMAMURA Kazuo, KIN Keiwa
アディポネクチン産生細胞シートを用いた新規大動脈瘤治療に関する研究

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Oct, 2010 - Mar, 2013

金啓和, 澤芳樹, 倉谷徹, 上野高義, 坂口太一, 宮川繁
Potential of microRNA as a biomarker for atherosclerotic aortic aneurysm

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

TORIKAI Kei, SAWA Yosiki, KURATANI Toru, SAKAGUCHI Taichi, SHIRAKAWA Yukitoshi, SHIMAMURA Kazuo, KIN Keiwa
Development of new treatment of heart failure using induced pluripotent stem cells-derived cardiomyocytes

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

NISHI Hiroyuki, SAWA Yoshiki
Analysis of relationship between microRNA expression and atrial fibrillation for development of new treatment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

KURATANI Toru, SAWA Yoshiki, MIYAGAWA Shigeru, SHIRAKAWA Yukitoshi, NISHI Hiroyuki, YOSHIKAWA Yasushi, TORIKAI Kei, KIN Keiwa
Development of cardiac regenerative medicine using a novel human somatic stem cell (Muse cell)

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

SOUGAWA Nagako, SAWA Yoshiki, MIYAGAWA Shigeru, NISHI Hiroyuki, YOSHIKAWA Yasushi, IDE Haruki
The development of novel therapy combined LVAD and regenerative medicine for severe heart failure patients

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2010 - 2012

MIYAGAWA Shigeru, KURATANI Toru, UENO Takayoshi, SAKAGUCHI Taichi, YOSHIKAWA Yasushi, YAMAUCHI Takashi, SHIRAKAWA Yukitoshi, SAWA Yoshiki, SHIMAMURA Kazuo
Development and the clinical application of the caqrdiovascular operation support program applied hydrodynamics simulation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2010 - 2011

UENO Takayoshi, SAWA Yoshiki, KURATANI Toru, SAKAGUCHI Taichi, SHIRAKAWA Yukitoshi, YOSHIKAWA Yasushi, YAMAUCHI Takashi, SHIMAMURA Kazuo
Development of Targeted Adiponectin Delivery System by Using Induced Adipocyte Cell-sheet

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2010 - 2011

SAWA Yoshiki, KURATANI Toru, UENO Takayoshi, SAKAGUCHI Taichi, SHIRAKAWA Yukitoshi, YOSHIKAWA Yasushi, YAMAUCHI Takashi, SHIMAMURA Kazuo
Development of new stent graft system using whole aortic navigation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2009 - 2011

SHIMAMURA Kazuo, SAWA Yoshiki, MATSUMIYA Goro, KURATANI Toru, SAKAGUCHI Taichi, SHIRAKAWA Yukitoshi, KIN Keiwa, UENO Takayoshi, MIYAGAWA Shigeru, YAMAUCHI Takashi

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