2018年3月1日
Temperature-responsive cell culture surface for cell-sheet tissue engineering and its design to express temperature-dependent cell attachment/detachment character
Kobunshi Ronbunshu
- ,
- 巻
- 75
- 号
- 2
- 開始ページ
- 174
- 終了ページ
- 186
- 記述言語
- 日本語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1295/koron.2017-0078
- 出版者・発行元
- Society of Polymer Science
In this review, we focus on the progress of temperature-responsive cell culture surface (TRCS), which is a poly(N-isopropylacrylamide) (PIPAAm) grafted surface, since the first report of temperature-responsive surfaces. We also show that the optimization of the grafted nano-scaled PIPAAm layer is essential to express temperature dependent cell attachment/detachment. Also, we describe the technologies required to readily fabricate cell sheets and TRCS in the near future, which are quantitative methods for cell adhesion/detachment processes from TRCS by using micro fluidic technique and a facile method for preparation of TRCS.
- ID情報
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- DOI : 10.1295/koron.2017-0078
- ISSN : 0386-2186
- SCOPUS ID : 85044417081