講演・口頭発表等

2010年12月1日

Effects of cyclic stretch on early response gene expressions in normal human pulmonary artery endothelial cells in vitro

2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
  • Kobayashi K
  • ,
  • Tanaka M
  • ,
  • Inaoka H
  • ,
  • Nebuya S
  • ,
  • Kokubo K
  • ,
  • Fukuoka Y
  • ,
  • Kobayashi H
  • ,
  • Noshiro M

The effects of cyclic stretch (within 30 min) on the expressions of early response genes in normal human pulmonary artery endothelial cells (HPAEC) were investigated using an in vitro stretch system. The investigated early response genes were early growth response gene 1 (Egr1), heatshock protein 4 (Hspa4), PTGS4 (cox2) and the inflammatory cytokines interleukin (IL)-1, IL-6 and IL-8. The genes of Egr1 and PTGS2 were upregulated at early stages by cycle stretch. ©2010 IEEE.

リンク情報
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-79952026472&partnerID=MN8TOARS
URL
http://orcid.org/0000-0001-6261-3783
DOI
https://doi.org/10.1109/BIBMW.2010.5703944