2016年5月
Supramolecular 1-D polymerization of DNA origami through a dynamic process at the 2-dimensionally confined air-water interface
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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- 巻
- 18
- 号
- 18
- 開始ページ
- 12576
- 終了ページ
- 12581
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c6cp01586g
- 出版者・発行元
- ROYAL SOC CHEMISTRY
In this study, a Langmuir-Blodgett (LB) system has been utilized for the regulation of polymerization of a DNA origami structure at the air-water interface as a two-dimensionally confined medium, which enables dynamic condensation of DNA origami units through variation of the film area at the macroscopic level (ca. 10-100 cm(2)). DNA origami sheets were conjugated with a cationic lipid (dioctadecyldimethylammonium bromide, 2C(18)N(+)) by electrostatic interaction and the corresponding LB-film was prepared. By applying dynamic pressure variation through compression-expansion processes, the lipid-modified DNA origami sheets underwent anisotropic polymerization forming a one-dimensionally assembled belt-shaped structure of a high aspect ratio although the thickness of the polymerized DNA origami was maintained at the unimolecular level. This approach opens up a new field of mechanical induction of the self-assembly of DNA origami structures.
- リンク情報
- ID情報
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- DOI : 10.1039/c6cp01586g
- ISSN : 1463-9076
- eISSN : 1463-9084
- Web of Science ID : WOS:000375689200022