論文

査読有り 国際誌
2014年5月13日

Proton beam therapy for a patient with a giant thymic carcinoid tumor and severe superior vena cava syndrome.

Rare tumors
  • Kaori Sugawara
  • ,
  • Masashi Mizumoto
  • ,
  • Haruko Numajiri
  • ,
  • Toshiki Ohno
  • ,
  • Kayoko Ohnishi
  • ,
  • Hitoshi Ishikawa
  • ,
  • Toshiyuki Okumura
  • ,
  • Hideyuki Sakurai

6
2
開始ページ
5177
終了ページ
5177
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.4081/rt.2014.5177
出版者・発行元
Page Press Publications

Surgical resection is the first choice for treatment of a thymic carcinoid tumor and radiotherapy is often performed as adjuvant therapy. Here, we report a case of an unresectable and chemoresistant thymic carcinoid tumor that was treated successfully using standalone proton beam therapy (PBT). The patient was a 66-year-old woman in whom surgical resection of the tumor was impossible because of cardiac invasion. Therefore, chemotherapy was administered. However, the tumor grew to 15 cm in diameter and she developed severe superior vena cava (SVC) syndrome. She was referred to our hospital and received PBT at a dose of 74 GyE in 37 fractions. PBT was conducted without severe early toxicities. After PBT, the tumor mildly shrunk to 13 cm in diameter and SVC syndrome almost disappeared. Subsequently, the tumor has continued to decrease in size slowly over the last 2 years and late toxicities have not been observed. Our experience with this case suggests that PBT may be effective for an unresectable thymic carcinoid tumor.

リンク情報
DOI
https://doi.org/10.4081/rt.2014.5177
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25002943
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083663
ID情報
  • DOI : 10.4081/rt.2014.5177
  • ISSN : 2036-3613
  • ISSN : 2036-3605
  • PubMed ID : 25002943
  • PubMed Central 記事ID : PMC4083663
  • SCOPUS ID : 84900447845

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