2005年3月
Proteomic LC-MS systems using nanoscale liquid chromatography with tandem mass spectrometry
JOURNAL OF CHROMATOGRAPHY A
- 巻
- 1067
- 号
- 1-2
- 開始ページ
- 73
- 終了ページ
- 83
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.chroma.2004.10.107
- 出版者・発行元
- ELSEVIER SCIENCE BV
Current nano-scale liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) approaches in proteome research are reviewed from an analytical perspective. For comprehensive analysis of cellular proteins, analytical methods with higher resolution, sensitivity, and wider dynamic range are required. Miniaturized LC coupled with tandem mass spectrometry is currently one of the most versatile techniques. In this review, the current status of nanoLC-MS/MS systems as well as data management systems is addressed. In addition, the future prospects for complete proteomics are discussed. (c) 2004 Elsevier B.V. All rights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.chroma.2004.10.107
- ISSN : 0021-9673
- PubMed ID : 15844511
- Web of Science ID : WOS:000227925800004